Accès ouvert
2026
article
OpenAlex
Claudia Campobasso, Pauline Henderix, Ekaterina Jalomo-Khayrova, Sara Bolognini et autres
The ability of Staphylococcus aureus to form biofilm and the emergence of multidrug-resistant strains make staphylococcal infections often chronic and difficult to treat. To face these challenges, alternative or adjunct strategies to antibiotics are urgently required. In this context, phage therapy gained …
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Accès ouvert
2025
article
OpenAlex
Claudia Campobasso, Elisa Fausti, Daria Bottai, Barbara Turchi et autres
OBJECTIVES: To explore phage therapy as an alternative for targeting multidrug-resistant bacterial strains, it is crucial to study phage-bacteria interaction under conditions that mimic in vivo environments. Recent studies have demonstrated that staphylococcal phage activity can be significantly hindered by human blood …
it
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Accès ouvert
2025
article
OpenAlex
Sara Bolognini, Caterina Ferretti, Claudia Campobasso, Elisabetta Trovato et autres
Pseudomonas aeruginosa is a major opportunistic pathogen with high levels of antibiotic resistance. Phage therapy represents a promising alternative for the treatment of difficult infections both alone and in combination with antibiotics. Here, we isolated and characterized three novel lytic myoviruses, Cisa, …
it
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Accès ouvert
2025
article
OpenAlex
Elisa Fausti, Andrea Bonacorsi, Novella Cesta, Cesira Giordano et autres
• Four newly isolated lytic phages showed no antibiotic resistance or virulence genes • Phages demonstrated rapid adsorption, short latent period and variable burst size • Phages were active against carbapenemase-producing Klebsiella pneumoniae strains • Phage cocktail enhanced lytic activity compared to …
it, be
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Accès ouvert
2024
article
OpenAlex
Fabian Kunisch, Claudia Campobasso, Jeroen Wagemans, Selma Yıldırım et autres
Spread of multidrug-resistant Pseudomonas aeruginosa strains threatens to render currently available antibiotics obsolete, with limited prospects for the development of new antibiotics. Lytic bacteriophages, the viruses of bacteria, represent a path to combat this threat. In vitro-directed evolution is traditionally applied to …
de, us, it, be
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Accès ouvert
2024
article
OpenAlex
Barbara Turchi, Claudia Campobasso, Arianna Nardinocchi, Jeroen Wagemans et autres
Abstract A novel temperate phage, named Hesat, was isolated by the incubation of a dairy strain of Staphylococcus aureus belonging to spa-type t127 with either bovine or ovine milk. Hesat represents a new species of temperate phage within the Phietavirus genus of …
it, be
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Accès ouvert
2022
article
OpenAlex
Alessandro Materazzi, Daria Bottai, Claudia Campobasso, Ann-Brit Klatt et autres
Staphylococcus aureus implant-associated infections are difficult to treat because of the ability of bacteria to form biofilm on medical devices. Here, the efficacy of Sb-1 to control or prevent S. aureus colonization on medical foreign bodies was investigated in a Galleria mellonella …
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Accès ouvert
2020
article
OpenAlex
Gabriele Senczuk, Lorenzo Guerra, Salvatore Mastrangelo, Claudia Campobasso et autres
Coat color is among the most distinctive phenotypes in cattle. Worldwide, several breeds share peculiar coat color features such as the presence of a fawn pigmentation of the calf at birth, turning over time to grey, and sexual dichromatism. The aim of …
it, Algérie, hu, tr
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