Zhuanghong Zhao

Determinants of rapid antiretroviral therapy initiation and its longitudinal clinical outcomes among people living with HIV in China: a single-center retrospective cohort study

Yongbing Sun, Bing Song, Juan Cheng, Chao Zhang et autres

Rapid initiation of antiretroviral therapy (Rapid ART, R-ART) is a cornerstone of the WHO/UNAIDS strategy to end the HIV/AIDS epidemic by 2030. However, evidence on the determinants and longitudinal clinical impact of R-ART in Chinese real-world populations remained poorly understood. This study …

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Safety Profile of COVID-19 Vaccines in HIV Patients Undergoing ART and Their Impact on Immune Recovery and HIV Reservoirs

Bing Song, Xinhua Wang, Lin Shen, Juan Cheng et autres

Abstract Background: While some studies have reported the impact of COVID-19 vaccines on immune recovery and human immunodeficiency virus (HIV) reservoirs in persons living with HIV (PLWH), their findings remain inconsistent. Furthermore, limited data exist on the safety of multiple COVID-19 vaccines …

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Causal role of immune cells in uveitis: a Mendelian randomization study

Jianping Pu, Zhuanghong Zhao, Yanping Duan, Jun Lü et autres

Background Uveitis refers to a group inflammation affecting the uvea, retina, retinal blood vessels as well as vitreous body, which is one of the common causes of blindness. There is growing evidence linking different types of immune cells to uveitis, although it …

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Experience of the Chinese Contribution: Impact Factors of Rapid ART and its Outcome

Yongbing Sun, Bing Song, Cheng Zhen, Rong Liang et autres

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Experience of the Chinese Contribution: Impact Factors of Rapid ART and its Outcome

Yongbing Sun, Tianjun Jiang, Bing Song, Cheng Zhen et autres

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Predictors of Coronavirus Disease 2019 Severity: A Retrospective Study of 64 Cases

Huihuang Huang, Bing Song, Zhe Xu, Yan‐Mei Jiao et autres

This study aimed to analyze the clinical characteristics and potential predictors of disease severity in patients with coronavirus disease 2019 (COVID-19). We retrospectively analyzed the clinical data from 64 (37 male and 27 female) patients with COVID-19. Their mean age was 47.8 …

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HSV-1 infection and pathogenesis in the tree shrew eye following corneal inoculation

Lihong Li, Yan Li, Xin Li, Yujie Xia et autres

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Application of amniotic membrane transplantation and autologous conjunctival flap covering on treatment of corneal ulcers

Daijiao Zhou, Zhuanghong Zhao

Corneal ulcer would be sometimes treated with amniotic membrane transplantation (AMT), autologous conjunctival flap (ACF) coverage or keratoplasty except for medication. The application of keratoplasty is restricted by corneal materials. Therefore, AMT and ACF coverage are widely used to heal corneal ulcers. …

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Establish animal models of herpes simplex keratitis

Dan Yan, Zhuanghong Zhao, Linkun Ma, Hui Zhang

Herpes simplex keratitis (HSK) is resulted from Herpes simplex virus type I(HSV-1), which features a high reoccurrence, high blindness incidence and incurability and is likely to lead to the dissolving of cornea, the formation of new vessels, and even perforating ulcer, being …

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