Bing Song

prevalence of syphilis among pregnant women in China: a systematic review and meta-analysis

Juan Cheng, Bing Song, Yongbin Sun, Huihuang Huang et autres

OBJECTIVE: Syphilis is a serious sexually transmitted infection that can cause severe adverse pregnancy outcomes. This study aimed to estimate the pooled prevalence of syphilis among pregnant women in China using systematic review and meta-analysis. METHODS: This systematic review and meta-analysis were …

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Challenges and strategies in clinical applications of CAR-T therapy for autoimmune diseases

Xiaomei Chen, Kaifan Liu, Bowen Liu, Shiyin Li et autres

Chimeric antigen receptor (CAR) T-cell therapy has demonstrated substantial efficacy against various hematological malignancies. The remarkable success of CAR-T cell therapy in targeting B-cell malignancies has generated significant interest in its potential application for treating autoimmune diseases (ADs). By engineering T cells …

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Impact on clinical biomarkers, immune recovery, and HIV reservoir dynamics of switching to EVG/c/FTC/TAF versus maintaining a non-INSTI-based regimen in virologically suppressed individuals

Yi Zhang, Hui-Huang Huang, Bing Song, Mengmeng Qu et autres

Abstract Background: Integrase Strand Transfer Inhibitors (INSTIs) have emerged as the preferred first-line antiretroviral therapy (ART) regimen globally, primarily due to their superior efficacy and favorable safety profile. However, in China, the high cost of INSTIs and their later market introduction have …

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Original data used in the paper Privacy-preserving Personalized Pricing and Matching for Ride-hailing Platforms.

Bing Song

Thymoquinone enhances efficacy of cervical cancer therapeutic vaccines via modulating CD8+ T cells

Yuxin Che, Bing Song, Jiaying Sun, Xue-Ting Zhao et autres

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The value of super microvascular imaging and shear wave elastography in evaluating synovial lesions in knee osteoarthritis

Min Jin, Lei Mi, Hanwen Li, Fuli Chen et autres

Objective This study investigates the value of super microvascular imaging (SMI) and shear wave elastography (SWE) in evaluating the relationship between synovial tissues and disease severity in knee osteoarthritis (KOA) patients. Materials and Methods Patients with KOA who visited our hospital between …

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AlphaEpi: Enhancing B Cell Epitope Prediction with AlphaFold 3

Feng Jiang, Yuzhi Guo, Hehuan Ma, Saiyang Na et autres

Accurately identifying conformational B-cell epitopes, which involve complex protein structures, is essential in modern immunology and vaccine development. Traditional methods like X-ray crystallography provide precise data but are costly and time-consuming. This has led to the rise of computational methods, especially deep …

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Biochemical and structural insights into a 5’ to 3’ RNA ligase reveal a potential role in tRNA ligation

Yingjie Hu, Víctor López, Hengyi Xu, James P. Pfister et autres

ATP-grasp superfamily enzymes contain a hand-like ATP-binding fold and catalyze a variety of reactions using a similar catalytic mechanism. More than 30 protein families are categorized in this superfamily, and they are involved in a plethora of cellular processes and human diseases. …

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[CXCL8 generates an immunosuppressive microenvironment in colorectal cancer through induction of M2 macrophage infiltration and inhibition of CD8+ T cell infiltration].

Ying Shao, Yan Lan, Bing Song, Jiaying Sun et autres

T cell infiltration to generate an immunosuppressive microenvironment in CRC.

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Safety Profile of COVID-19 Vaccines in HIV Patients Undergoing ART and Their Impact on Immune Recovery and HIV Reservoirs

Bing Song, Xinhua Wang, Lin Shen, Juan Cheng et autres

Abstract Background: While some studies have reported the impact of COVID-19 vaccines on immune recovery and human immunodeficiency virus (HIV) reservoirs in persons living with HIV (PLWH), their findings remain inconsistent. Furthermore, limited data exist on the safety of multiple COVID-19 vaccines …

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Comparison of the efficacy of Mitraclip in functional versus degenerative mitral regurgitation：A systematic review and meta-analysis

xuhua Li, Qiyuan Bai, Zhili Wei, Shidong Liu et autres

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Biochemical and structural insights into a 5’ to 3’ RNA ligase reveal a potential role in tRNA ligation

Yingjie Hu, Víctor López, Hengyi Xu, James P. Pfister et autres

Abstract ATP-grasp superfamily enzymes contain a hand-like ATP-binding fold and catalyze a variety of reactions using a similar catalytic mechanism. More than 30 protein families are categorized in this superfamily, and they are involved in a plethora of cellular processes and human …

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