Zhaoxia Wu

A transcriptomic and metabolomic approach to elucidate the synergistic anti-browning effect of combined L-cysteine and Trehalose treatment on fresh-cut stem lettuce and the mechanisms underlying the maintenance of cell membrane integrity

Ronghua Wu, Zixuan Liu, Chunfan Guo, Jingxuan Ma et autres

cn (code pays fourni par la source)

Multi-scale hierarchical regulation of starch chain length distribution and its consequential impact on starch digestibility: From molecular structure to granular degradation

Zixuan Liu, Tianshuang Xia, Chunfan Guo, Jingxuan Ma et autres

Starch chain length distribution (CLD) hierarchically modulates starch digestibility from enzyme recognition to granular degradation. This review summarizes CLD characteristics of amylose (short, medium, long chains) and amylopectin (A, B1, B2, B3 chains). The hierarchical regulatory rules are elucidated at molecular (chain …

cn, kr (code pays fourni par la source)

Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer

Xinyue Li, Yimin Chu, Ying Xu, Fengli Zhou et autres

Background: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Oxaliplatin-based chemotherapy is a cornerstone of treatment for many CRC patients; however, the development of chemoresistance severely limits its therapeutic efficacy and remains a major clinical challenge. The identification of …

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Neuroprotective potential of Semen Ziziphi Spinosae extracts against LPS-induced inflammation in astrocytes: a comparative study of polar solvents

Jun Ma, Ru Wang, Yan Wang, Zixuan Liu et autres

Semen Ziziphi Spinosae (SZS), a traditional Chinese medicine, has been extensively studied in animal models of insomnia in vitro, but its application in cell models has been limited. Therefore, we selected a lipopolysaccharide (LPS)-induced astrocyte model to investigate the therapeutic effects and …

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The Effects of Semen Ziziphi Spinosae Extract on LPS-Induced Astrocyte Gene Expression and Metabolites

Jun Ma, Ru Wang, Yaping Xu, Yan Wang et autres

Background/Objectives: Semen Ziziphi Spinosae (SZS), a medicinal and edible traditional Chinese herb, has been widely used to treat insomnia. As critical regulators of the central nervous system, astrocytes play a pivotal role in maintaining sleep homeostasis. However, the mechanisms by which SZS …

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Evaluation of aroma characteristics of Eriocheir sinensis meat as affected by environmental ammonia

Tianyu Wang, Hang Lü, Yuanyong Tian, Hui Zhao et autres

Ammonia accumulation in aquaculture systems affects the sensory quality of Eriocheir sinensis , and mechanisms linking ammonia to aroma changes remain unclear. This study investigated how ammonia exposure in aquatic environments (0, 10.47, and 41.87 mg/L total ammonia-N, 48 h) alters aroma …

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Evolution of XDR Pseudomonas aeruginosa ST463 strains with two plasmids harboring multiple antimicrobial resistance genes

Yinfei Fang, Meijun Song, Yisha Zhang, Zhaoxia Wu et autres

ABSTRACT The extensively drug-resistant (XDR) Pseudomonas aeruginosa ST463 strains, which co-harbor plasmid-associated metallo-β-lactamase (MBL) and bla KPC-2 genes, exhibit significant resistance and virulence, posing great clinical treatment challenges. Here, we report on three XDR P. aeruginosa ST463 strains, PA64, PA3117, and PA30, …

cn, in, au (code pays fourni par la source)

Machine learning for early prediction of the infection in patients with urinary stone after treatment of holmium laser lithotripsy

Weiqi Xia, Miaomiao Zhang, Xiaowei Zheng, Zhaoxia Wu et autres

Patients after holmium laser lithotripsy have a certain probability of getting postoperative infection. An early and accurate diagnosis of postoperative infection allows a timely administration of appropriate antibiotic treatment. However, doctors can not accurately determine whether the patient has the infection. Here, …

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Emergence of an XDR Klebsiella pneumoniae ST5491 strain co-harboring NDM-5, MCR-1.1, tmexCD1-toprJ1, and a novel plasmid carrying CTX-M-15

Yinfei Fang, Xiangchen Li, Zhaoxia Wu, Fang Ye et autres

Objective The rapid emergence of antimicrobial resistance (AMR) in Klebsiella pneumoniae poses a significant global health threat. The study aimed to analyze and describe the genomic architecture and resistance mechanisms of an extensively drug-resistant (XDR) K. pneumoniae isolate, KP09, by focusing on …

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Comparison of flexible ureteroscopy with flexible and navigable suction ureteral access sheath and mini-percutaneous nephrolithotripsy for the treatment of impacted upper ureteral stones: a retrospective study

Haiyang Tang, Zhaoxia Wu, Jiayu Liu, Jie Li

Background and objective The treatment of impacted upper ureteral stones remains a significant challenge for urologists. Standard treatment protocols often favor Mini-Percutaneous Nephrolithotripsy (Mini-PCNL). It has been supposed to be associated with a higher stone clearance rate and a lower incidence of …

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Ethanol extract of propolis relieves exercise-induced fatigue via modulating the metabolites and gut microbiota in mice

Shan Huang, Xiaofei Yang, Jun Ma, Chen Li et autres

Background Propolis, a natural mixture rich in bioactive compounds, has shown the potential to relieve exercise-induced fatigue. However, the underlying mechanism remains unclear. This study aimed to explore the anti-fatigue effects of ethanol extract of propolis (EEP) and its potential mechanisms. Methods …

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Molecular mechanisms of ascorbic acid affected by ozone in fresh-cut kiwifruit: Insights from salicylic acid synthesis and signal transduction

Yajing Wang, Jun Ma, Tianyu Wang, Liyan Rong et autres

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