Andrey Fadeev

The Connection of the Pineal Cyst with the Peculiarities of the Structure of the Brain and the Presence of Certain Personality Traits

A. V. Shilova, Natalia I Ananieva, L. V. Lukinа, N. Yu. Safonova et autres

Aim. To study the psychological characteristics and microstructural changes of the brain, according to magnetic resonance imaging (MRI), in healthy volunteers with pineal cyst to determine their clinical significance. Design. A prospective case — control study. Materials and methods. The study involved …

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ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells

Andrey Fadeev, Patricia Mendoza-García, Uwe Irion, Jikui Guan et autres

Significance Neuroblastoma is a pediatric tumor arising from the neural crest. Dysregulation of the receptor tyrosine kinase ALK has been linked to neuroblastoma, making it important to understand its function in native conditions. In zebrafish, a related receptor—Ltk—is also expressed in neural …

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ALKALs are in vivo ligands for ALK family Receptor Tyrosine Kinases in the neural crest and derived cells

Andrey Fadeev, Patricia Mendoza Garcia, Uwe Irion, Jikui Guan et autres

Abstract Mutations in Anaplastic Lymphoma Kinase (ALK) are implicated in somatic and familial neuroblastoma, a paediatric tumour of neural crest-derived tissues. Recently, biochemical analyses have identified secreted small ALKAL proteins (FAM150, AUG) as potential ligands for human ALK and the related Leukocyte …

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Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish

Prateek Mahalwar, Ajeet Pratap Singh, Andrey Fadeev, Christiane Nüsslein‐Volhard et autres

The conspicuous striped coloration of zebrafish is produced by cell-cell interactions among three different types of chromatophores: black melanophores, orange/yellow xanthophores and silvery/blue iridophores. During color pattern formation xanthophores undergo dramatic cell shape transitions and acquire different densities, leading to compact and …

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Zebrafish Leucocyte tyrosine kinase controls iridophore establishment, proliferation and survival

Andrey Fadeev, Jana Krauß, Ajeet Pratap Singh, Christiane Nüsslein‐Volhard

The zebrafish striped pattern results from the interplay among three pigment cell types; black melanophores, yellow xanthophores and silvery iridophores, making it a valuable model to study pattern formation in vivo. It has been suggested that iridophore proliferation, dispersal and cell shape …

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The role of Tight Junction Protein 1a and Leukocyte Tyrosine Kinase in the development and organisation of pigment cells in the Zebrafish

Andrey Fadeev

Vertebrates possess a unique structure, the neural crest, which contributes cells to a wide spectrum of tissues and organs, amongst them are pigment cells or chromatophores. In mammals and birds only one type of chromatophore is present – the melanocytes. However, more …

Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning

Andrey Fadeev, Jana Krauß, Hans Georg Frohnhöfer, Uwe Irion et autres

Zebrafish display a prominent pattern of alternating dark and light stripes generated by the precise positioning of pigment cells in the skin. This arrangement is the result of coordinated cell movements, cell shape changes, and the organisation of pigment cells during metamorphosis. …

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Author response: Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning

Andrey Fadeev, Jana Krauß, Hans Georg Frohnhöfer, Uwe Irion et autres

The striking horizontal striped pattern of the zebrafish makes it a decorative addition to many home aquariums. The stripes are a result of three different pigment cells interacting with each other, and first begin to emerge when the animal is two to …

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Pigment Pattern Formation in the Guppy,Poecilia reticulata, Involves the Kita and Csf1ra Receptor Tyrosine Kinases

Verena A. Kottler, Andrey Fadeev, Detlef Weigel, Christine Dreyer

Males of the guppy (Poecilia reticulata) vary tremendously in their ornamental patterns, which are thought to have evolved in response to a complex interplay between natural and sexual selection. Although the selection pressures acting on the color patterns of the guppy have …

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Pigment Pattern Formation in the Guppy, Poecilia reticulata, Involves the Kita and Csf1ra Receptor

Verena A. Kottler, Andrey Fadeev, Detlef Weigel, Christine Dreyer

Males of the guppy (Poecilia reticulata) vary tremendously in their ornamental patterns, which are thought to have evolved in response to a complex interplay between natural and sexual selection. Although the selection pressures acting on the color patterns of the guppy have …

Isolation and physicochemical properties of tankyrase of human embryonic kidney cells of line 293

N. N. Sidorova, Andrey Fadeev, A. N. Kuimov

We have isolated and purified endogenous cytosolic tankyrase from human embryonic kidney cells of line 293. Our data confirm a model of De Rycker and Price who consider that tankyrase is a master scaffolding protein capable of regulating assembly of large protein …

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