Hilal Karakaş

Prognostic role of smoking in metastatic renal cell carcinoma in real-world data from the Turkish Oncology Group Kidney Cancer Consortium (TKCC)

Hatice Bölek, Elif Sertesen Camoz, Omer F. Kuzu, Hilal Karakaş et autres

Smoking has been implicated as a potential factor influencing cancer progression and outcomes in various malignancies, including metastatic renal cell carcinoma (mRCC). This study aimed to evaluate the effect of smoking status on treatment outcomes in mRCC patients, with a focus on …

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The impact of smoking on nivolumab outcomes in renal cell carcinoma: real-world data from the Turkish Oncology Group Kidney Cancer Consortium

Elif Sertesen, Hatice Bölek, Omer F. Kuzu, Hilal Karakaş et autres

BACKGROUND: The study aims to evaluate the effect of smoking status on treatment results in patients with metastatic renal cell carcinoma (RCC) treated with nivolumab in the second and following lines of therapy. MATERIALS AND METHODS: The Turkish Oncology Group Kidney Cancer …

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Uric acid level in metastatic renal cell carcinoma treated with nivolumab: a Turkish Oncology Group Kidney Cancer Consortium (TKCC) study

Serhat Sekmek, Hatice Bölek, Omer F. Kuzu, Elif Sertesen Çamöz et autres

Aims To investigate the effect of uric acid level on prognosis in patients with metastatic renal cell carcinoma (mRCC) treated with nivolumab.Materials and methods This retrospective study utilized data from the Turkish Oncology Group Kidney Cancer Consortium (TKCC), which is a multicenter …

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A current comprehensive role of immune-checkpoint inhibitors in resectable non-small cell lung cancer: A narrative review

Safa Can Efil, Burak Bi̇lgi̇n, Furkan Ceylan, Hilal Karakaş et autres

OBJECTIVE: The objective of this article is to review the efficacy, safety, and evidence for current use and potential future uses of immune-checkpoint inhibitors (ICIs) in the management of resectable non-small cell lung cancer (NSCLC). DATA SOURCES: A literature review was carried …

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The Evaluation of SCUBE-1 and sCD40L Levels in Diabetic Nephropathy

Hilal Karakaş, Mehmet Ali Eren, İsmail Koyuncu, İdris Kırhan et autres

Aim: There is a close link between diabetic nephropathy and atherosclerotic heart disease. We aimed to evaluate the changes of SCUBE-1 and sCD40L, which play role in the course of atherosclerosis, with the progression of nephropathy in patients with type 2 diabetes.Material …

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The evaluation of thiol/disulphide homeostasis in diabetic nephropathy

Mehmet Ali Eren, İsmail Koyuncu, Hatice İncebıyık, Hilal Karakaş et autres

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The Evaluation of Thiol/Disulfide Homeostasis in Diabetic Nephropathy

Mehmet Ali Eren, İsmail Koyuncu, Hatice İncebıyık, Hilal Karakaş et autres

Abstract Thiol/disulfide homeostasis plays a critical role in antioxidant defense, detoxification, apoptosis, enzyme activities, transcription and cellular signal transduction. It is known that thiol levels decrease due to thiol oxidation, disulfide levels increase and thiol/disulfide ratio increase in diabetics. However, it is …

Diyabetik nefropatide thiol/disülfit dengesinin araştırılması

Hilal Karakaş, HATİCE İNCEBIYIK, Mehmet Ali Eren, Ismail Koyuncu et autres

An Investigation on The Usage of Plant Material in Open Green Spaces in Kastamonu City Center

Çiğdem SAKICI, Hilal Karakaş, Merve Damla Kesimoğlu

Açık yeşil alanlar hem fizyolojik hem psikolojik açıdan son derece önemlidir. Çalışma kapsamında Kastamonu kent merkezinde bulunan yoğun kullanıma sahip sekiz kamusal açık yeşil alanda kullanılan bitki materyali değerlendirilmiş olup bu alanlarda bitki sayımı ve incelemeleri yapılarak odunsu bitkilerin türleri, sayıları, özellikleri …