Ismail Koyuncu

Chemical Profiling and Multi‐Bioactive Potential of Onosma nigricaulis

Gün Binzet, Pınar Küce Çevik, Ismail Koyuncu, Rıza Binzet

ABSTRACT In Turkish folk medicine, Onosma species are used to treat wounds, burns, and ulcers. This study investigated the chemical composition and biological activities of ethanolic (EE) and petroleum ether (PEE) extracts from the endemic Onosma nigricaulis (Boraginaceae). GC–MS analysis identified 25 …

tr (code pays fourni par la source)

Effects of Vitamin E on Redox balance in regulating thiol/disulfide homeostasis in sepsis: An antioxidant therapy perspective

Veli Fahri Pehlivan, Başak Pehlivan, Erdoğan Duran, Abdullah Taşkın et autres

BACKGROUND: Sepsis, a life-threatening condition resulting from a dysregulated host response to infection, is associated with high mortality and remains a major global health burden. Sepsis is characterized by an imbalance between oxidative stress and inflammation, leading to disruption of thiol-disulfide homeostasis, …

tr, us (code pays fourni par la source)

Anesthetic-Induced Disruption of Amino Acid and Carnitine Profiles: A Metabolomic Comparison of Propofol and Thiopental in Hepatocytes

Veli Fahri Pehlivan, Başak Pehlivan, Erdoğan Duran, Ismail Koyuncu et autres

Background/Objectives: Propofol and Thiopental are widely used anesthetic agents, yet their cumulative and high-dose effects on hepatic metabolism remain insufficiently characterized. This study aimed to evaluate the impact of supra-therapeutic concentrations of these agents on carnitine and amino acid metabolism in AML12 …

tr (code pays fourni par la source)

Propofol ve Tiyopental, HEK-293 Hücrelerinde Amino Asit ve Karnitin Metabolizmasını Bozar: Mitokondriyal Toksisiteye Dair Bulgular

Veli Fahri Pehlivan, Başak Pehlivan, Erdoğan Duran, Ismail Koyuncu et autres

Opening New Roads for Multi‐Directional Functional Applications Through In Vitro Chemical and Biological Analysis of Zoegea leptaurea L. Extracts

Sakina M. Ahmed Yagi, Giovanni Caprioli, Gabriele Rocchetti, Filomena Nazzaro et autres

ABSTRACT Zoegea leptaurea L. has been traditionally used to treat digestive issues, headaches, and skin diseases. This study aimed to evaluate, for the first time, the phenolic content, antioxidant potential, enzyme inhibition, cytotoxic anti‐biofilm/probiotic properties of the flowers, stems, leaves, and aerial …

Soudan, it, tr, fr (code pays fourni par la source)

The Biopotential of Bellardia trixago in Replacing Synthetic Compounds for Health‐Promoting Applications: Is It a Promising Candidate?

Mehmet Veysi Çetiz, Sakina M. Ahmed Yagi, Kouadio Ibrahime Sinan, İsmail Şenkardeş et autres

ABSTRACT Bellardia trixago (L.) All. (family Orobanchaceae) is a facultative hemiparasitic plant used traditionally to cure many diseases. The present study was designed to evaluate the phenolic constituents, antioxidant, enzyme inhibitory, and cytotoxic properties of the aerial parts of B. trixago . …

tr, Soudan, it (code pays fourni par la source)

Linking the chemical profile with the biological activities of Reaumuria alternifolia from Turkish flora

Milena Terzić, Stefano Dall’Acqua, Stefania Sut, Abdullahi İbrahim Uba et autres

rs, it, tr (code pays fourni par la source)

A multifunctional natural treasure based on a “one stone, many birds” strategy for designing health-promoting applications: Tordylium apulum

Nilofar Nilofar, Gokhan Zengin, Abdullahi İbrahim Uba, Nurgül Abul et autres

tr, it, in, cz, sk, by (code pays fourni par la source)

Unlocking the functional potential of Nitraria schoberi extracts using chemical fingerprinting, biological efficiencies, in silico and network pharmacological approaches

Stefano Dall’Acqua, Sakina Yagi, Stefania Sut, Abdullahi İbrahim Uba et autres

it, Soudan, fr, tr (code pays fourni par la source)

Diyabetik nefropatide thiol/disülfit dengesinin araştırılması

Hilal Karakaş, HATİCE İNCEBIYIK, Mehmet Ali Eren, Ismail Koyuncu et autres

Albino sıçanların Ultraviyole B ile indüklenmiş deri hasarı modelinde arı sütünün antiapoptotik, antigenotoksik ve antioksidan etkilerinin araştırılması

HATICE UCE OZKOL, Murat Çetin Rağbetli, Yasin Tülüce, Hatice Uce Özkol et autres

Albino Sıçanlarda Ultraviyole A ile İndüklenmiş Deri Hasarı Modelinde Kafeik Asit Fenetil Ester ve Endosteinin Antiapoptotik, Antigenotoksik ve Antioksidan Etkilerinin Araştırılması

Yasin Tülüce, Murat Çetin Rağbetli, Esma Süldür ZEREN, Ismail Koyuncu et autres