Linghan Tian

Integrated bulk, single-cell and spatial transcriptomic analyses identify KIFC1 as a driver of malignant progression in lung adenocarcinoma

Linghan Tian, Yuanbiao Wang, Li Huang, Yuanyuan Meng et autres

cn, us (code pays fourni par la source)

Prognostic value of brown adipocyte-related genes in colorectal cancer: a multi-omics and Mendelian randomization study

Hongbin He, Yuanbiao Wang, Linghan Tian, Zihan Wang et autres

BACKGROUND: Brown adipocytes are vital in cancer's emergence and progression. However, such significance of brown adipocytes-related genes (BARGs) in colorectal cancer (CRC) still awaits exploration. The potential prognostic mechanisms of BARGs in CRC were aimed to be explored in this study. METHODS: …

cn (code pays fourni par la source)

Topical application of a placental mesenchymal stem cell-embedded biomaterial hydrogel accelerates the repair of radiation-induced skin damage: a double-blind randomized phase II clinical trial

Linghan Tian, Zhibo Han, Zhibo Han, Ming Jiang et autres

BACKGROUND: Radiation-induced skin injury (RSI) is a common complication of radiation therapy, that severely reduces the quality of life of patients, and there is currently no gold standard for treatment. Placental mesenchymal stem cells (PMSCs) have emerged as a promising therapeutic approach …

cn (code pays fourni par la source)

C-Arg9-APCR3-VHL promotes β-catenin degradation via the VHL-mediated ubiquitin–proteasome system in APC-mutant colorectal cancer

Pei Luo, Wenjun Shi, Linghan Tian, Yinan Li et autres

cn (code pays fourni par la source)

TRIM21 promotes type I interferon by inhibiting the autophagic degradation of STING via p62/SQSTM1 ubiquitination in systemic lupus erythematosus

Chen Li, Ang Ma, Yu Bai, Zitao Liu et autres

The cGAS-STING signaling pathway serves as a pivotal surveillance mechanism for cytosolic double-stranded DNA (dsDNA) detection in mammalian systems. While STING-mediated type I interferon production is crucial for host defense, sustained activation of this pathway contributes to autoimmune pathologies, including systemic lupus …

cn (code pays fourni par la source)

Interaction between MUC1 and β-catenin promotes transformation of adenomas to adenocarcinomas in Familial Adenomatous Polyposis

Yinan Li, Wenjun Shi, Pei Luo, Xianshuo Cheng et autres

cn (code pays fourni par la source)

Whole transcriptome scanning and validation of negatively related genes in UC-MSCs

Linghan Tian, Weibin Wang, Xuzhen Li, Yan Chen et autres

Background Human umbilical cord mesenchymal stem cells (UC-MSCs) are one of the most extensively researched stem cell types due to their potential for multi-lineage differentiation, secretion of regenerative factors, modulations of immunological activities, and the release of regenerative substances and influence immunological …

cn (code pays fourni par la source)

Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv et autres

BACKGROUND: The centromere protein O (CENPO) is an important member of the centromere protein family. However, the role of CENPO in pan-cancer and immune infiltration has not been reported. Here, we investigated the role of CENPO in pan-cancer and further validated its …

cn (code pays fourni par la source)

Prognostic and immune infiltrative biomarkers of CENPO in pan- cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv et autres

Abstract Background The centromere protein O (CENPO) is an important member of the centromere protein family. However, the role of CENPO in pan–cancer and immune infiltration has not been reported. Here, we investigated the role of CENPO in pan–cancer and further validated …

cn (code pays fourni par la source)

Additional file 17 of Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv et autres

Additional file 17.

Additional file 10 of Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv et autres

Additional file 10.

Additional file 9 of Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv et autres

Additional file 9.