Yinan Li

Extended-release calcifediol for secondary hyperparathyroidism in Chinese adults with stage 3 or 4 chronic kidney disease: a randomized trial

Ming Fang, Hao Yan, Huijuan Mao, Hong Ren et autres

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Fabric-based sandwich-structured irreversible thermochromic photonic crystal indicator for cold chain transportation

Hui Zhang, Xinyang Li, Yinan Li, Wanyang Sun et autres

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Association between triglyceride levels and upper urinary tract calcium stones recurrence

Jie Yang, Jun Cai, Yinan Li, Jiangwei Du et autres

BACKGROUND: Triglyceride (TG) is a known risk factor for kidney stones, but its association with stone recurrence remains unclear. This study aimed to investigate the relationship between serum TG levels and recurrence of upper urinary tract calcium stones. METHOD: Patients with upper …

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Healthcare-associated infections and antimicrobial use in South China: a large-scale point prevalence survey of 338 hospitals in Guangdong Province

Jiajin Chen, Yan Liu, Fang Yu, Xia Li et autres

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Protocol of the Dragon study: Drug-coated balloon compared with cutting balloon in treatment of arteriovenous fistula stenosis

Ruzhou Cao, Qihong Ni, P G Wang, Hong Ye et autres

BACKGROUND: Endovascular therapy is the preferred option for arteriovenous fistula dysfunction. The aim of this trial is to compare the 12-month efficacy and safety outcomes of cutting balloon with the drug-coated balloon. METHODS AND ANALYSIS: The DRAGON study is a multicenter, prospective, …

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The efficacy of sequential radiotherapy after the combination of TACE with lenvatinib and anti-PD-1 antibodies for unresectable HCC

Xiangye Ou, Jinhai Li, Rongjian Pan, Deyi Liu et autres

BACKGROUND: Triple therapy of transcatheter arterial chemoembolization (TACE) combined with lenvatinib and anti-PD-1 antibodies has demonstrated excellent efficacy in unresectable hepatocellular carcinoma (uHCC). However, tumor drug resistance is still a major problem and the rate of complete response in uHCC following triple …

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Association between renal function and simple renal cyst growth: a retrospective study

Yanhao Shen, Yinan Li, Dong Wang, Dong Wang et autres

OBJECTIVE: Simple renal cysts (SRC) are associated with a high incidence of proteinuria and renal insufficiency. However, the effects of renal function, particularly estimated glomerular filtration rate (eGFR), on SRC size remains unclear. This study aimed to investigate the impact of renal …

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Multicenter, Randomized Phase 2 Study Evaluating the Efficacy and Safety of HRS-5965 in Patients with Primary IgAN

Jicheng Lv, Yan Zha, Shuxin Liu, Dongwen Zheng et autres

Background: Complement system activation plays a significant role in the glomerular inflammation of IgAN. HRS-5965 is a novel, selective small molecule inhibitor of complement factor B by inhibiting complement alternative pathway activation. This study aimed to evaluate the efficacy and safety of …

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C-Arg9-APCR3-VHL promotes β-catenin degradation via the VHL-mediated ubiquitin–proteasome system in APC-mutant colorectal cancer

Pei Luo, Wenjun Shi, Linghan Tian, Yinan Li et autres

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Vitamin D supplementation inhibits atherosclerosis through repressing macrophage-induced inflammation via SIRT1/mTORC2 signaling

Yuli Wang, Qihong Ni, Yongjie Yao, Shu Lu et autres

To the Editor: Peripheral artery disease (PAD) is a prevalent vascular condition characterized by arterial narrowing or occlusion, primarily due to atherosclerosis. Approximately 17.5% of patients with PAD develop acute lower limb ischemia due to vulnerable atherosclerotic plaque rupture, which significantly impacts …

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Cerebrospinal Fluid p-Tau181/Amyloid Beta 42 Ratio Identifies Lymphatic-Venous Anastomosis Patients Who Respond to and Benefit from the Surgery for Relief of Cognitive Impairment with a Diagnostic Accuracy of 0.744

Guangqi Xu, Qinghua Zhang, Yinan Li, Aimin Du et autres

High Resolution Image Download MS PowerPoint Slide Responders (R) and Non-Responders (NR) to lymphatic-venous anastomosis (LVA) surgery for relief of cognitive impairment show significant difference in their p-tau181/Aβ42 ratios via enzyme-linked immunosorbent assay (ELISA) of their cerebrospinal fluid (CSF). LVA involves the …

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Risk factors of poor outcomes in ANCA-associated vasculitis: a single-center study

Axi Age, Ruihong Huang, Yinan Li, Juan Pei

OBJECTIVE: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare disease with high rate of end-stage kidney disease (ESKD) and mortality. We aimed to investigate the risk factors for ESKD and/or death in AAV patients. METHODS: Seventy-eight AAV patients diagnosed from November …

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