Carolyn Hyde

THE SOLUBLE EPOXIDE HYDROLASE INHIBITOR GSK2256294 DECREASES LPS- INDUCED CYTOKINE MRNA EXPRESSION IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS

P Jalali, Carolyn Hyde, D. Gilroy, David Bishop‐Bailey

This study focused on a group of 49 high-yielding dairy cows (primarily Holstein Friesians) and how their interactions with wall-mounted automated brushes correlated to their mobility (also described as lameness) score (AHDB 0–3 system. Of the 49 animals in the study, 48 …

C-Type Natriuretic Peptide (CNP) Inhibition of Interferon-γ-Mediated Gene Expression in Human Endothelial Cells In Vitro

Amy Day, Zoe Jameson, Carolyn Hyde, Bigboy H. Simbi et autres

Cardiovascular diseases, including atherosclerosis, now account for more deaths in the Western world than from any other cause. Atherosclerosis has a chronic inflammatory component involving Th1 pro-inflammatory cytokines such as IFN-γ, which is known to induce endothelial cell inflammatory responses. On the …

gb (code pays fourni par la source)

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

Dubravka Škalamera, Max V. Ranall, Benjamin M. Wilson, Paul Leo et autres

In response to the growing need for functional analysis of the human genome, we have developed a platform for high-throughput functional screening of genes overexpressed from lentiviral vectors. Protein-coding human open reading frames (ORFs) from the Mammalian Gene Collection were transferred into …

au (code pays fourni par la source)