Abstract 2872: Methods of assessment of polysialyltransferase inhibitors for treatment of tumor cell dissemination
Xiaoxiao Guo, Jodie R. Malcolm, Anjana Patel, Marrwa M. Ali et autres
Abstract Polysialic acid (polySia) decorates the surface of NCAM (neuronal cell adhesion molecule) on neuroendocrine tumors, notably neuroblastoma and small cell lung cancer, and is strongly associated with poor prognosis and aggressive disease in patients in the clinic [1]. PolySia modulates tumor …
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