Sudarshan Kumar Sharma

PARP inhibitor maintenance therapy with niraparib in patients with primary advanced or recurrent endometrial cancer receiving dostarlimab plus chemotherapy

Matthew A. Powell, Lars Christian Hanker, Sharad Ghamande, Lucy Gilbert et autres

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SURVIVAL AND SAFETY OUTCOMES IN PART 1 OF THE ENGOT-EN6-NSGO/GOG-3031/RUBY TRIAL OF DOSTARLIMAB PLUS CARBOPLATIN-PACLITAXEL IN THE PRESENCE OF COMMON COMORBIDITIES

Brian M. Slomovitz, Kristina Lindemann, Matthew Powell, Filip Frühauf et autres

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LUGA: Lightweight Uncertainty-Guided Sensing Resolution Adaptation for Energy Efficient Radar Processing

Sudarshan Kumar Sharma, Jinhyeok Park, Hemant Kumawat, Saibal Mukhopadhyay

Static Frequency Modulated Continuous Wave (FMCW) radar sensing treats all scenes uniformly, resulting in inefficient resource usage given that naturally occurring scenes vary in complexity. Prior adaptive schemes depend on compute heavy online learning methods, leading to high compute cost and latency, …

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Real-Time Front-End Adaptation for Energy-Efficient mmWave Radar Sensor

Jinhyeok Park, Sudarshan Kumar Sharma, W. J. Wang, Alex Saad-Falcon et autres

Radar sensor systems often suffer from suboptimal performance in dynamic environments due to static front-end configurations. While cognitive radar approaches have been proposed to address this issue through adaptive processing, they are often computationally intensive and unsuitable for real-time deployment. This work …

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Post hoc tipping point and multiple imputation analyses to determine the impact of early censored patients in the ENGOT-EN6-NSGO/GOG-3031/RUBY trial

Bhavana Pothuri, Jørn Herrstedt, Evelyn L. Fleming, Олена Миколаївна Сухіна et autres

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A plain language summary publication of patients’ survival with endometrial cancer treated with dostarlimab plus carboplatin-paclitaxel

Matthew A. Powell, Line Bjørge, Lyndsay J. Willmott, Z. Novák et autres

Summary What is the purpose of this PLS-P? The purpose of this plain language summary of publication is to help you understand recent findings from Part 1 of the RUBY study (full name ENGOT-EN6/GOG3031/RUBY trial). • Researchers sometimes study new combinations of …

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An End-to-End Simulator for Testing Array Processing Algorithms

Alex Saad–Falcon, Yashas Devarajaiah, Wei‐Chun Wang, Sudarshan Kumar Sharma et autres

Testing array processing algorithms requires realistic data that captures both hardware non-idealities and environmental complexities, but collecting comprehensive experimental datasets is often impractical. We present an open-source end-to-end simulator that addresses this challenge by providing a modular, GPU-accelerated framework for evaluating array …

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Broadband Beamforming Using Low-Bit Precision Dimensionality Reduction

Coleman DeLude, Sudarshan Kumar Sharma, Wei Chun Wang, Saibal Mukhopadhyay et autres

The demands of modern multi-sensor array applications put stress on every aspect of the processing pipeline, resulting in extremely power-hungry systems. In this paper we investigate a new method of broadband beamforming which, leveraging reduced dimension Slepian processing, has been demonstrated to …

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A Mixed-signal Computing-in-Memory Solver for Integer Constrained Least Square Problems

Narasimha Vasishta Kidambi, Wen Wang, Daehyun Kim, Sudarshan Kumar Sharma et autres

An 8T-SRAM-based Mixed-Signal Computing-In-Memory (MS-CIM) is demonstrated in 65nm CMOS for solving Integer-Constrained Least Square problems. The test-chip consumes 21.76mW (at 1.2V) and requires 720us to solve a 20-input 16-output Integer Constrained Least Square (ICLS) problem generating solutions with quality ranking in …

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Impact of adding the immune checkpoint inhibitor atezolizumab to first-line chemotherapy on progression-free survival in poor-prognosis ovarian cancer: A retrospective analysis from the IMagyn050 trial

Benoît You, Charles K Anderson, Sabrina Chiara Cecere, Aurore Carrot et autres

PURPOSE: Adding the anti-PD-L1 antibody atezolizumab to frontline chemotherapy-bevacizumab regimen did not improve progression-free survival (PFS) in ovarian cancer (OC) patients in IMagyn050 trial. This post-hoc analysis assessed the efficacy of atezolizumab in a subgroup of patients with particularly poor prognosis, as …

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Cyto-diagnosis of unilateral adrenal histoplasmosis mimicking a primary adrenal neoplasm in an immunocompetent patient

Lalita Negi, Sudarshan Kumar Sharma, Kavita Mardi, Shivani Sood et autres

Histoplasmosis mostly shows bilateral adrenal gland involvement in immunocompromised patients. Our case is of a 43 years old immunocompetent male patient having pain in the left flank for one month. CECT abdomen revealed a well-defined hypodense mass measuring 64×61×56 mm with necrotic …

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Energy-Efficient and Reliable Sensor Platform Based on Analog-to-Feature Extraction

Minah Lee, Sudarshan Kumar Sharma, Wei Chun Wang, Saibal Mukhopadhyay

This paper introduces the Artificial Intelligence-Driven Energy-efficient Analog-to-Learning system (AIDEAL), an AI-enabled in-sensor computing platform designed to enhance energy efficiency in edge devices through in situ data processing. AIDEAL extracts task-relevant features from analog inputs, significantly reducing the data volume for digitization …

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