Bhavna Kumar

Fabrication and characterization of buccal films of propranolol hydrochloride: an in-vitro and ex-vivo analysis

Prakash Kumar, Jagannath Sahoo, Bhavna Kumar, Abhijeet Ojha et autres

The aim of current examination was to formulate propranolol hydrochloride (PHCL) loaded buccal films by combining polyvinyl alcohol with guar gum using solvent casting process. The formulated films were assessed for a variety of measures including physical evaluation, in vitro drug permeation, …

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A scoping review of herbal and allopathic remedies: Insights into liver damage, diagnostic methods, and hepatoprotective strategies

Bhavna Kumar, N.S. Disha

Drug-induced liver injury (DILI) is a significant yet often underdiagnosed issue resulting from both pharmaceutical and herbal agents.While conventional allopathic drugs, including ursodeoxycholic acid, silymarin, and N-acetylcysteine, have established therapeutic roles in managing liver conditions through mechanisms such as cell membrane stabilization, …

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Enhancing Latent Tuberculosis Infection Treatment Adherence with Mobile Health Intervention: A Quasi-Experimental Study

Rohitashwa Kumar, Manmohan Singhal, N Ravishankar, Abhijeet P Sinha et autres

Introduction: While detecting active TB is central to public health efforts, modelling indicates that reducing latent TB through preventive therapy is crucial. Current regimens mitigate risk but are lengthy and have side effects, necessitating support for uninterrupted treatment. This paper presents the …

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Nutraceutical Herbs As Immuno-Inflammatory Agents

Rahul Tiwari, Bhavna Kumar, Rupa Gupta, Dheeraj Bisht et autres

Immuno-inflammatory agents have the ability to transform the immune system by improving immune defences to boost reaction of body against several infectious or exogenous injuries, or suppressing the abnormal immune response caused any immune disorders. Currently, nutraceuticals products, which have positive control …

Neuroprotective action of hordenine against the Aluminium Chloride (AlCl3) induced Alzheimer's diseases & associated memory impairment in experimental rats

Mohit Agrawal, Manmohan Singhal, Bhupesh Chander Semwal, Swamita Arora et autres

To investigate the neuroprotective action of hordenine against the cognitive dysfunction induced by aluminium chloride (AlCl3) in Wistar rats Rats were given oral doses of hordenine (25 and 50 mg/kg), donepezil (5 mg/kg), and AlCl3 (175 mg/kg) for 28 days. During the …

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Synthesis and Characterization of Baicalein-loaded Aquasomes: An In vitro and In silico Perspective for Diabetes Mellitus

Vinay Goyal, Bhavna Kumar, Diwya Kumar Lal, Poorvi Varshney et autres

Background: Millions of individuals worldwide suffer from metabolic abnormalities induced by diabetes. Baicalein, a flavonoid, has shown several properties in various treatments with potential properties, including anti-inflammatory, antioxidant, and anti-diabetic properties. Practically, its application is hindered due to low solubility in aqueous …

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In-vitro and In-silico Examinations on Baicalein-loaded Solid Lipid Nanoparticles for Neurodegeneration

Mansi Varshney, Bhavna Kumar, Poorvi Varshney, Diwya Kumar Lal et autres

Background:: In the current scenario, most of the population affected by neurogenera-tive disorders like Alzheimer's, Parkinson's, Huntington's, etc., exist among the 10% population 65 years of age group. Neurodegenerative diseases are characterised as chronic and progressive disorders that occur due to the …

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Polyphenols Targeting MAP Kinase Signaling Pathway in Neurological Diseases: Understanding Molecular Mechanisms and Therapeutic Targets

Fahadul Islam, Sumon Roy, Mehrukh Zehravi, Shyamjit Paul et autres

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Neuroprotective Cognitive Effects of Nose-to-brain Delivered Linagliptin Loaded Polymeric Nanosuspension in Animal Model

Deepika Joshi, Bhavna Kumar, Manmohan Singhal, Samir Bhargava

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A Mechanistic Insight on Phytoconstituents Delivering Hypoglycemic Activity: A Comprehensive Overview

Shraddha Singh Raghav, Bhavna Kumar, Neeraj Kumar Sethiya, Ankur Kaul

Diabetes is a long-term (chronic), challenging lifestyle (metabolic) disorder in which the body cannot regulate the amount of sugar in the blood and majorly affecting endocrine system and metabolic functions. Its complications majorly affect the neurons (as developing neuropathy), kidney (as nephropathy), …

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Titre indisponible

Deepika Sharma, Shubham Tyagi, Bhavna Kumar

Ocuserts or ophthalmic inserts are “Sterile preparation in the form of solid or semisolid, whose size and shape are specially designed to be applied to the eyes”. The most frequently used dosage forms (ophthalmic solutions and suspensions) are compromised in their effectiveness …

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Formulation and Evaluation of Polymeric Nanomicelles of Gliptin for Controlled Drug Delivery

Deepika Sharma, Bhavna Kumar

Objective: The main objective of the study was to develop gliptin loaded polymeric nanomicelles by direct dissolution method. The comparative evaluation studies were performed to study the effect of polymer concentration on particle size, entrapment efficiency, loading capacity and drug release of …

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