Jakub Kłącz

The Covid-19 Pandemic Restrictions and Its Impact on Surgical Treatment of Male Infertility Due To Spermatic Cord Varices – A Single Academic Medical Center Experience

Katarzyna Gross-Kępińska, Jakub Kłącz, Mateusz Czajkowski, Kevin Miszewski et autres

pl (code pays fourni par la source)

The immunoreactivity of GLI1 and VEGFA is a potential prognostic factor in kidney renal clear cell carcinoma

Anna Kotulak‐Chrząszcz, Jacek Kieżun, Mateusz Czajkowski, Marcin Matuszewski et autres

Kidney renal clear cell carcinoma (KIRC) is the most common type of kidney cancer and its pathogenesis is strongly associated with VHL-HIF-VEGF signaling. SHH ligand is the upstream SHH pathway regulator, while GLI1 is its major effector that stimulates as a transcription …

pl (code pays fourni par la source)

Expression levels of sonic hedgehog pathway genes and their targets are upregulated in early clear cell renal cell carcinoma

Anna Kotulak‐Chrząszcz, Agnieszka Rybarczyk, Jakub Kłącz, Marcin Matuszewski et autres

Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive subtype of kidney cancer, with high mortality rates worldwide. The sonic hedgehog (SHH) molecular cascade is altered in various malignancies in tumorigenesis, and several SHH pathway inhibitors have been considered …

pl (code pays fourni par la source)

The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines’ gene expression

Mateusz Czajkowski, Piotr Wierzbicki, Anna Kotulak‐Chrząszcz, Katarzyna Czajkowska et autres

PURPOSE: To assess the expression of selected cytokines in penile lichen sclerosus (PLS) and associate them with the occurrence of micro-incontinence (MI) in different stages of PLS. METHODS: The skin biopsies from 49 PLS affected, and 13 from nonlesional foreskins (healthy control …

pl, us (code pays fourni par la source)

Analysis of Clinicopathological Factors Influencing Survival in Patients with Renal Cell Carcinoma and Venous Tumor Thrombus

Łukasz Zapała, Sumit Kumar Sharma, Michał Kunc, Piotr Zapała et autres

This study aimed to define patients with renal cell cancer and coexisting tumor thrombus in order to address concerns regarding survival and prognostic factors after radical surgery. Several prognostic factors for overall survival (OS) were assessed in patients treated surgically at five …

pl (code pays fourni par la source)

Male Circumcision Due to Phimosis as the Procedure That Is Not Only Relieving Clinical Symptoms of Phimosis But Also Improves the Quality of Sexual Life

Mateusz Czajkowski, Katarzyna Czajkowska, Karolina Zarańska, Alicja Giemza et autres

INTRODUCTION: Male circumcision is recognized as the most effective method of phimosis treatment. Analyzing the literature, the information about the influence of male circumcision due to phimosis for patients' subjective symptoms such as itching, burning, penile pain, pain during intercourse, and quality …

pl (code pays fourni par la source)

Evaluation of non-invasive tests as diagnostic tools in assessment of bladder outlet obstruction severity in men with anterior urethral stricture

Jakub Krukowski, Adam Kałużny, Jakub Kłącz, Anna Piatkowska et autres

INTRODUCTION: The aim of this article was to evaluate non-invasive tests, which were typically used in preoperative diagnosis of male patients with anterior urethral strictures in the assessment of the urethral resistance caused by urethral occlusion. MATERIAL AND METHODS: A total of …

pl (code pays fourni par la source)

Lichen Sclerosus and Phimosis – Discrepancies Between Clinical and Pathological Diagnosis and Its Consequences

Mateusz Czajkowski, Anton Żawrocki, Katarzyna Czajkowska, Jakub Kłącz et autres

pl (code pays fourni par la source)

Expression of the Sonic Hedgehog pathway components in clear cell renal cell carcinoma

Anna Kotulak‐Chrząszcz, Jakub Kłącz, Marcin Matuszewski, Zbigniew Kmieć et autres

Clear cell renal cell carcinoma (ccRCC) is the most common and the most aggressive histopathological subtype of kidney cancer, with patients exhibiting high mortality rates for metastatic tumors. The Sonic Hedgehog (SHH) pathway serves a crucial role in embryonic development. The abnormal …

pl (code pays fourni par la source)

Primary urethral carcinoma – unexpected cause of urethral stricture. Case report and review of the literature.

Jakub Krukowski, Mateusz Czajkowski, Jakub Kłącz, Olga Wawrzaszek et autres

Primary cancer of urethra (PCU) is one of rarest malignancies of the urinary tract. In early stages this type of cancer presents non specific symptoms which can be mistaken with more common urethral strictures. That is why the PCU is frequently recognize …

pl (code pays fourni par la source)

Prognostic significance of VHL, HIF1A, HIF2A, VEGFA and p53 expression in patients with clear‑cell renal cell carcinoma treated with sunitinib as first‑line treatment

Piotr Wierzbicki, Jakub Kłącz, Anna Kotulak‐Chrząszcz, Agata Wrońska et autres

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell cancer, characterized by the highest mortality rate among other RCC subtypes due to the occurrence of metastasis and drug resistance following surgery. The Von Hippel‑Lindau tumor suppressor (VHL)‑hypoxia‑inducible …

pl (code pays fourni par la source)

Phimosis : histopathological examination is always necessary

Mateusz Czajkowski, Anton Żawrocki, Katarzyna Czajkowska, Jakub Kłącz et autres