Chitalu Chanda

Scaling-up tuberculosis preventive therapy to HIV-negative contacts of bacteriologically confirmed TB cases aged 5 years and above – Lessons from a tuberculosis preventive therapy surge activity in Zambia

Peter Mwaba, Innocent Mwaba, Minyoi Mubita Maimbolwa, Chitalu Chanda et autres

While tuberculosis preventive therapy (TPT) coverage among people living with HIV in Zambia has improved, uptake among HIV-negative contacts aged ≥5 years remains low. Despite evidence showing that TPT can reduce TB incidence by up to 60% in HIV-negative individuals, there is …

Zambie, mn, no, us (code pays fourni par la source)

Determinants of favorable treatment outcomes in multidrug-resistant tuberculosis in Zambia: A retrospective cross sectional study, 2018–2022

Dorcas Kalaba, Chitalu Chanda, Muhammad Mputu, Hamooya M. Benson et autres

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is a persistent public health challenge in Zambia, with favorable treatment outcomes remaining below the World Health Organization target of 90%. However, limited national evidence on treatment outcomes and their determinants hinders the development of effective programmatic responses. …

Zambie, us, ca (code pays fourni par la source)

Predictors of tuberculosis mortality among patients on treatment: A retrospective cohort study at a rural general hospital in Zambia

Collins Mukubesa, Lukundo Siame, Malan Malumani, Faceroy Nkole et autres

BACKGROUND: Despite decades of global efforts and the availability of curative and preventive measures, tuberculosis (TB) continues to be the world's leading infectious disease cause of mortality, particularly in resource-limited settings. However, in developing countries, there is limited evidence on determinants of …

kw, Afrique du Sud, Zambie (code pays fourni par la source)

Burden of Nosocomial Surgical Site Infections at Three Tertiary Hospitals in Copperbelt Province, Zambia

Seke M.E. Kazuma, Chitalu Chanda, Bright Chirengendure, Joshua Chisanga et autres

Introduction: Hospital-acquired infections (HAI) are nosocomial infections that develop after 48 hours of admission, and surgical site infections (SSI) are a major and significant contributor, with high morbidity and mortality, catastrophic healthcare costs, prolonged hospital stays, and poor quality of life. This …

Zambie (code pays fourni par la source)

Factors contributing to the measles outbreak reported at Kabinga Rural Health Centre in Kanchibiya District

Virginia Maposa, Kaziwe Sikambale, Kevin Zimba, Margaret Chishimba et autres

Zambie, us, nl (code pays fourni par la source)

A Cohort Study of Traffic in Theatre as a Risk for Surgical Site Infection at Three Tertiary Hospitals in the Copperbelt Province, Zambia

Seke M.E. Kazuma, Mumba Chalwe, Chitalu Chanda, Muleya Inambao et autres

Introduction: The rate of operating-theatre room nosocomial infections is estimated at 10% of surgical site infections (SSI) in postoperative wounds. Earlier studies have suggested that restricting traffic by head count and reducing the number of door-openings of the operating room could reduce …

Prevalence and associated factors of prediabetes among adults living with HIV receiving dolutegravir-based antiretroviral therapy in Zambia

Lukundo Siame, Chilufya Nalomba, Michelo H. Miyoba, Nema Siame et autres

As people living with HIV (PLHIV) experience longer survival globally, including in Zambia, the widespread adoption of dolutegravir-based antiretroviral therapy (ART) as the preferred first-line regimen has been accompanied by growing recognition of metabolic complications such as prediabetes as an emerging public …

Afrique du Sud, Zambie, us (code pays fourni par la source)

Metabolic syndrome and its risk factors among adults living with HIV receiving antiretroviral therapy in Zambia: an ambidirectional cohort study

Benson Malambo Hamooya, Samuel Bosomprah, Sepiso Kenias Masenga, Katongo Hope Mutengo et autres

Effective antiretroviral therapy (ART) has significantly improved the survival of people living with HIV (PWH) while concurrently ushering in a new challenge of cardiometabolic complications. Despite advancements in treatment, there is a paucity of epidemiological and longitudinal data on metabolic changes among …

Zambie, us (code pays fourni par la source)

Treatment failure and associated factors among people living with HIV on second-line antiretroviral therapy in Zambia

Kaziwe Sikambale, Chitalu Chanda, Victor Daka, Eustarckio Kazonga et autres

BACKGROUND: Treatment failure in second-line antiretroviral therapy (ART) among people living with HIV remains a critical concern in Zambia. This study investigated virological failure and factors associated with treatment failure among patients on second-line ART at two tertiary hospitals in Zambia. METHODS: …

Zambie, ca (code pays fourni par la source)

Prevalence and determinants of poor outcome in patients with chronic kidney disease in low-income countries in sub-Saharan Africa: a systematic review.

Chitalu Chanda, Nomanthombi Johnson, Natasha Ngwenya, Christabel Silavwe et autres

Chronic kidney disease (CKD) is a significant health burden globally, associated with high healthcare costs and mortality rates. In Africa, the prevalence of CKD is estimated at around 10-15% in adults, with factors such as HIV, diabetes mellitus, hypertension, and cardiovascular disease …

Zambie (code pays fourni par la source)

Seroprevalence and risk factors of Brucella antibodies among patients seeking medical attention at health facilities in selected districts of Western Province in Zambia

Armand Mayindu Mambote, Ruth Lindizyani Mfune, Victor Daka, Melai Mubanga et autres

Background: Brucellosis is a neglected zoonosis that impacts public health and livestock productivity. It is endemic in Zambia, particularly in regions with extensive livestock farming, such as the Western Province. Objective: This study aimed to determine the seroprevalence of Brucella antibodies and …

Zambie (code pays fourni par la source)

Scaling-up tuberculosis preventive therapy to over five-years old HIV-negative contacts of bacteriologically confirmed TB cases – lessons from a tuberculosis preventive therapy surge activity in Zambia

Peter Mwaba, Innocent Mwaba, Minyoi Mubita Maimbolwa, Chitalu Chanda et autres

Abstract Background While tuberculosis preventive therapy (TPT) coverage among people living with HIV in Zambia has improved, uptake among HIV-negative contacts aged ≥5 years remains low. Despite some evidence that TPT can reduce TB incidence by up to 60% in HIV-negative individuals, …

Zambie, no (code pays fourni par la source)