Burden of Nosocomial Surgical Site Infections at Three Tertiary Hospitals in Copperbelt Province, Zambia
Rattachement africain : Zambie. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Introduction: Hospital-acquired infections (HAI) are nosocomial infections that develop after 48 hours of admission, and surgical site infections (SSI) are a major and significant contributor, with high morbidity and mortality, catastrophic healthcare costs, prolonged hospital stays, and poor quality of life. This study aimed to determine the prevalence of nosocomial SSI and their susceptibility profiles at three teaching hospitals in Zambia. Methodology: This prospective cohort study was conducted at three tertiary hospitals in the Copperbelt Province of Zambia. Results: A total of 1 122 participants were included in the study. Of these, 468 were female and 654 were male. The prevalence of nosocomial SSI in the three teaching hospitals was 21%, representing 95 of the 478 participants. The five most common cultured organisms were Staphylococcus aureus (23%), Enterobacter agglomerans (14%), Pseudomonas aeruginosa (11%), Proteus mirabilis (10%), and Escherichia coli (9%). Most isolates were sensitive to meropenem (15%), chloramphenicol (15%), metronidazole (15%), and septrin (11%) and were resistant to ciprofloxacin (36%), azithromycin (13%), gentamycin (11%), and penicillin (10%). Conclusion: The prevalence of Nosocomial SSI was 21%. The cultured bacterial isolates were Staphylococcus aereus (23%), Enterobacter agglomerans (14%), Pseudomonas aeruginosa (11%), Proteus mirabilis (10%), and Escherichia coli (9%). Susceptibility results showed sensitivity to meropenem (15%), chloramphenicol (15%), metronidazole (15%), and septrin (11%), and resistance to ciprofloxacin (36%), azithromycin (13%), gentamycin (11%), and penicillin (10%). Our study recommends chloramphenicol or meropenem in combination with metronidazole as first- and second-line treatments, respectively, for nosocomial SSI at the three tertiary hospitals.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Burden of Nosocomial Surgical Site Infections at Three Tertiary Hospitals in Copperbelt Province, Zambia
- Date Crossref
- 24/06/2026
- Éditeur
- European Open Science Publishing
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University Teaching Hospital Zambie (code pays fourni par la source)Établissement de santé
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Zambia Forestry College Zambie (code pays fourni par la source)Université ou école supérieure
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University of Zambia Zambie (code pays fourni par la source)Université ou école supérieure
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Ndola Teaching Hospital Ndola Teaching Hospital, Zambie (pays nommé en fin d’affiliation)Établissement de santé
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Arthur Davison Children’s Hospital Zambie (pays nommé en fin d’affiliation)Établissement de santé
University Teaching Hospital (Zambie), Zambia Forestry College (Zambie) et University of Zambia (Zambie), avec 2 autres affiliations. Pays d’affiliation : Zambie.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.