Sara Botschuijver

Excel datasheet showing raw EMG data acquired during colonic distensions

Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto et autres

Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift …

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Degradation of Resistant α-1,4-glucan by Vaginal Gardnerella Species is Associated with Bacterial Vaginosis

Rosanne Hertzberger, Sara Morselli, Sara Botschuijver, Lisa Himschoot et autres

This study investigates the degradation of resistant α-1,4-glucan by vaginal bacterial species, with a focus on Gardnerella spp., to elucidate its role in bacterial vaginosis (BV). The ability of Gardnerella vaginalis, Gardnerella swidsinskii, Gardnerella leopoldii, Gardnerella piotii, Lactobacillus iners, and Lactobacillus crispatus …

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Gut fungi in irritable bowel syndrome : A painful recognition

Sara Botschuijver

This thesis focused on the role of fungi in the irritable bowel syndrome (IBS). IBS is a common, stress related, functional gastrointestinal disorder, characterized by chronic abdominal pain. A part of IBS patients show increased perception of pain to a rectal stimulus …

Painful interactions: Microbial compounds and visceral pain

Isabelle van Thiel, Sara Botschuijver, Wouter J. de Jonge, Jurgen Seppen

Visceral pain, characterized by abdominal discomfort, originates from organs in the abdominal cavity and is a characteristic symptom in patients suffering from irritable bowel syndrome, vulvodynia or interstitial cystitis. Most organs in which visceral pain originates are in contact with the external …

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Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Sara Botschuijver, Sophie A. van Diest, Isabelle van Thiel, Rafael Simone Saia et autres

Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may result from fungal induced release of mast …

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643 - Reversal of Visceral Hypersensitivity in Rat by a Proprietary Combination of Essential Oils from Peppermint and Caraway Coincides with Mycobiome Modulation

Sara Botschuijver, Olaf Welting, Evgeni Levin, Daniele Maria‐Ferreira et autres

Reversal of visceral hypersensitivity in rat by Menthacarin ® , a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation

Sara Botschuijver, Olaf Welting, Evgeni Levin, Daniele Maria‐Ferreira et autres

Abstract Background Irritable bowel syndrome ( IBS ) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. Menthacarin ® is a …

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Intestinal Fungal Dysbiosis Is Associated With Visceral Hypersensitivity in Patients With Irritable Bowel Syndrome and Rats

Sara Botschuijver, Guus Roeselers, Evgeni Levin, Daisy Jonkers et autres

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Fecal Transplantation and Mycobiome Analysis Showing the Relevance of Fungi in Post Stress Visceral Hypersensitivity of Maternal Separated Rats

Sara Botschuijver, Guus Roeselers, Evgeni Levin, Daisy Jonkers et autres

Peer Review Report For: Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; peer review: 3 approved]

Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto et autres

Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift …

nl (code pays fourni par la source)

Peer Review Report For: Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; peer review: 3 approved]

Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto et autres

Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift …

nl (code pays fourni par la source)

Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats

Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto et autres

BACKGROUND: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift …

nl, cn (code pays fourni par la source)