Steffen Leth

Immunological dysfunction associated with SARS-CoV-2 persistence in immunocompromised patients

I. Johannsen, Line K. Vibholm, Giacomo Schmidt Frattari, Míriam Rosás-Umbert et autres

Advances in coronavirus disease 2019 management has led to decreases in disease burden; however, immunocompromised patients continue to experience prolonged or persistent infections. We investigated immunological factors associated with time to viral clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

dk, au, ru (code pays fourni par la source)

How a long COVID rehabilitation intervention works: refining its programme theory through a realist-informed qualitative study

Trine Brøns Nielsen, Lisa Gregersen Oestergaard, Jemma L. Hawkins, Claus Vinther Nielsen et autres

BACKGROUND: Although the majority of individuals infected with SARS-CoV-2 recover without treatment, some individuals experience persistent symptoms (long COVID), which may negatively affect their activities and roles of everyday life, leaving them with a profound rehabilitation need. In response to the emergence …

dk, gb (code pays fourni par la source)

Disability pension and sick leave in people with HIV compared with the background population – a nationwide population-based matched cohort study

Lars Haukali Omland, Alban Senn, Anne Zutavern, Mathias W. Orban et autres

OBJECTIVES: People with HIV (PWH) are unable to get private disability insurance on a regular basis in contrast with individuals with other chronic diseases. We aimed to estimate the risk of public disability pension and work absence due to sickness for PWH …

dk, de (code pays fourni par la source)

Construct validity of self-reported and interview-guided administration methods of the Danish version of the post-COVID−19 functional Status scale

Lotte Sørensen, Jane Agergaard, Trine Brøns Nielsen, Berit Schiøttz‐Christensen et autres

Introduction: The Post-COVID-19 Functional Status (PCFS) scale was quickly adopted into COVID-19 research and clinical practice worldwide to monitor functional status and recovery. The scale has been translated into Danish, and three different administration methods have been employed. However, clinicians have expressed …

dk (code pays fourni par la source)

Characterising disability in patients with long COVID–does gender matter? an analytic cross-sectional study

Cecilia Hee Laursen, Trine Brøns Nielsen, Steffen Leth, Berit Schiøttz‐Christensen et autres

BACKGROUND: Long COVID affects patients' daily functioning and activity participation. However, gender-specific differences remain insufficiently explored despite well-documented effects of gender on health outcomes. This study examines gender differences in sociodemographic characteristics, employment status, sick leave, and mental fatigue among individuals with …

dk (code pays fourni par la source)

Risk of schizophrenia spectrum disorders among people with HIV: a nationwide, population-based, matched cohort study

Cecilie V. Vollmond, Malte Mose Tetens, Jan Gerstoft, Gitte Kronborg et autres

BACKGROUND: Mental health has become an area of concern among people with HIV (PWH). We aim to assess whether the risk of schizophrenia spectrum disorders (SSD) is increased among PWH. To examine whether such risks are affected by familial factors we also …

dk (code pays fourni par la source)

Myasthenic crisis with respiratory failure caused by COVID-19

Troels Ulrik Eliasen, Steffen Leth, Nilanjan Dey

Myasthenic crisis is a severe complication of myasthenia gravis (MG) characterized by respiratory failure. This case report presents a 24-year-old woman admitted with respiratory distress, eventually diagnosed with myasthenic crisis triggered by COVID-19. Initial symptoms included throat pain and dysphagia with no …

dk (code pays fourni par la source)

Genetic Landscape and Mitochondrial Metabolic Dysregulation in Patients Suffering From Severe Long COVID

Kristoffer Skaalum Hansen, Sofie E. Jørgensen, Cagla Cömert, Berit Schiøttz‐Christensen et autres

Long COVID represents a significant global health challenge with an unclear etiology. Alongside accumulating evidence of mitochondrial dysfunction in patients with acute SARS-CoV-2 infection, a symptomatic overlap exists between long COVID and mitochondrial disorders. However, the genetic underpinnings of mitochondrial dysfunction in …

dk (code pays fourni par la source)

Exploring the Immunological Factors Impacting SARS-CoV-2 Persistence in Patients with Secondary Immunodeficiencies

Line K. Vibholm, Giacomo Schmidt Frattari, Míriam Rosás-Umbert, Irene Harder Tarpgaard et autres

dk (code pays fourni par la source)

Bipolar disorder in people with HIV

Cecilie V. Vollmond, Malte Mose Tetens, Jan Gerstoft, Gitte Kronborg et autres

OBJECTIVES: To assess whether bipolar disorders are associated with the risk of HIV infection and whether the risk of bipolar disorders is increased among people with HIV (PWH) and their siblings. DESIGN: Nationwide, population-based, combined matched nested case-control and cohort study of …

dk (code pays fourni par la source)

Survival among people with HIV and their families in Denmark 1995–2021: a nationwide population-based cohort study

Caroline Eves, Lars Haukali Omland, Jan Gerstoft, Gitte Kronborg et autres

Background: Survival among people with HIV (PWH) has vastly improved globally over the last few decades but remains lower than among the general population. We aimed to estimate time trends of survival among PWH and their families from 1995 to 2021. Methods: …

dk (code pays fourni par la source)

Survival Among Persons with HIV and Their Families – a Nationwide, Population-Based Cohort Study, Denmark, 1995-2021

Caroline Eves, Lars Haukali Omland, Jan Gerstoft, Gitte Kronborg et autres

dk (code pays fourni par la source)