Alexey Vladimir Protopopov

Associations of ANRIL rs1333049 and LPA rs10455872 with clinical markers of vascular damage in patients with hereditary dyslipidemias under 44 years of age

V. S. Emelyanchik, A. M. Moiseeva, Diana Viktorovna Dmitrenko, E. Yu. Emelyanchik et autres

Aim. To study the impact of ANRIL rs1333049 and LPA rs10455872 polymorphisms on the clinical status of patients with heterozygous familial hypercholesterolemia (FH) and hyperlipoproteinemia(a) (hyperLP(a)). Material and methods. A total of 171 patients aged 3 to 44 years were examined. Lipid …

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Assessment of the need pacemaker implantation following aortic valve replacement with combined cardiac surgery

Yu. Yu. Stolbikov, Gennady V. Matyushin, Alexey Vladimir Protopopov, Е. В. Самохвалов et autres

Aim. To evaluate the risk factors for the development of cardiac conduction disorders and to determine their significance in temporary and permanent pacemaker implantation in patients after surgical aortic valve replacement and other combined cardiac surgical interventions. Material and methods. The analysis …

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Ultrasound catheter thrombolysis for the treatment of pulmonary embolism: the first experience in the Russian Federation

Evgeny V. Merkulov, Andrew S. Tereshchenko, Goar K. Arutyunyan, Dmitry V. Pevzner et autres

Treatment of pulmonary embolism (PE) is still an urgent problem worldwide due to complications of systemic thrombolytic therapy. This review examines ultrasound catheter thrombolysis using the EKOS system, indications, patient selection and current state of the issue. The device itself, appropriate manipulations …

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2024 Clinical practice guidelines for Acute myocardial infarction with ST segment elevation electrocardiogram

Oleg V. Averkov, GOHAR HARUTYUNYAN, Dmitry Viktorovich Duplyakov, Е. В. Константинова et autres

Russian Society of Cardiology (RSC) With the participation of: the Association of Cardiovascular Surgeons, the Russian Society of Emergency Medical Care, the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM) Approved by the Research and Practical Council of the Ministry of …

FFR-Negative Nonculprit High-Risk Plaques and Clinical Outcomes in High-Risk Populations: An Individual Patient-Data Pooled Analysis From COMBINE (OCT-FFR) and PECTUS-obs

Rick H. J. A. Volleberg, Andi Rroku, Jan‐Quinten Mol, Renicus Suffridus Hermanides et autres

BACKGROUND: Despite fractional flow reserve (FFR)–guided deferral of revascularization, recurrent events in patients with diabetes or after myocardial infarction remain common. This study aimed to assess the association between FFR-negative but high-risk nonculprit lesions and clinical outcomes. METHODS: This is a patient-level …

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Incidence of atrioventricular conduction disturbances and need for pacemaker implantation in patients after endovascular aortic valve replacement

Yu. Yu. Stolbikov, Gennady V. Matyushin, Alexey Vladimir Protopopov, Е. В. Самохвалов et autres

The aim of the study was to evaluate predictors of cardiac conduction disturbance associated with increased risk of temporary and permanent pacemaker implantation after endovascular aortic valve replacement (TAVR). Material and methods. We analyzed patients who underwent surgical treatment for aortic valve …

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EXPERIENCE IN IMPLEMENTING MENTORING AT A MEDICAL UNIVERSITY

Alexey Vladimir Protopopov, Irina A. Soloveva, E.A. Yurieva, Ekaterina A. Alekseeva

Differences in non-flow limiting non-culprit plaque characteristics after myocardial infarction in patients with versus without chronic kidney disease

Rick H. J. A. Volleberg, J H Q Mol, Rik S. Hermanides, Martijn Meuwissen et autres

Abstract Background Patients with chronic kidney disease (CKD) are at increased risk for recurrent cardiovascular events after myocardial infarction compared to patients with preserved renal function. This disparity may be related to differences in plaque morphology. Purpose To compare non-flow limiting non-culprit …

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Sex differences in plaque characteristics of fractional flow reserve-negative non-culprit lesions after myocardial infarction

Rick H. J. A. Volleberg, Jan‐Quinten Mol, Anouar Belkacemi, Renicus Suffridus Hermanides et autres

Abstract Background and aims Recurrent events after myocardial infarction (MI) are common and often originate from native non-culprit (NC) lesions that are non-flow limiting. These lesions consequently pose as targets to improve long-term outcome. It is, however, largely unknown whether these lesions …

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Incidence and predictors of 2-year mortality following percutaneous left atrial appendage occlusion in the EWOLUTION trial

Errol W. Aarnink, Hueseyin Ince, Stephan Kische, Evgeny Pokushalov et autres

AIMS: Sufficient survival time following left atrial appendage occlusion (LAAO) is essential for ensuring the efficacy and cost-effectiveness of this strategy for stroke prevention. Understanding prognostic factors for early mortality after LAAO could optimize patient selection. In the current study, we perform …

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Thrombus extraction in acute ischemic stroke: three years of experience at the regional vascular center

Pavel Gennadievich Shnyakin, N.V. Litvinyuk, Alexey Vladimir Protopopov, I. V. Atanyan et autres

From a modern perspective, the key to successful treatment of ischemic stroke is early reperfusion with systemic thrombolytic therapy and thrombus extraction. Thrombectomy is the only reliable method of recanalization in patients with thrombosis of a large cerebral artery. Despite the fact …

Phenotype of heterozygous familial hypercholesterolemia caused by deletion of LDLR gene exons 2-10: a case report

A. M. Moiseeva, Olga Nikolaevna Ivanova, V. S. Emelyanchik, E. Yu. Emelyanchik et autres

Introduction. Analysis and comparison of clinical and functional characteristics of patients with familial hypercholesterolemia (FH) with molecular genetics data make it possible to clarify the disease nature and determine the management strategy taking into account the clinical and genetic status. Considering that …

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