Angeliki Kolovou

Cost-Effectiveness of α2 Agonists for Intravenous Sedation in Patients With Critical Illness

Stephen Morris, Nazir Lone, Cathrine McKenzie, Christopher John Weir et autres

Importance: Propofol and the α2 agonists dexmedetomidine and clonidine are used for sedation in patients with critical illness receiving mechanical ventilation. Evidence about the cost-effectiveness of intravenous (IV) sedation with these medications is lacking. Objective: To investigate the cost-effectiveness of dexmedetomidine-, clonidine-, …

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Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients

Timothy Simon Walsh, Richard Anthony Parker, Leanne M. Aitken, Cathrine McKenzie et autres

Importance: Whether α2-adrenergic receptor agonist-based sedation, compared with propofol-based sedation, reduces time to extubation in patients receiving mechanical ventilation in the intensive care unit (ICU) is uncertain. Objective: To evaluate whether dexmedetomidine- or clonidine-based sedation reduces duration of mechanical ventilation compared with …

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Intravenous Vitamin C for Patients Hospitalized With COVID-19

Simin Aysel Florescu, Dragos Stanciu, Mihaela Florentina Zaharia, Alma Gabriela Kosa et autres

Importance: The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain. Objective: To determine whether vitamin C improves outcomes for patients with COVID-19. Design, Setting, and Participants: Two prospectively harmonized randomized clinical trials enrolled critically ill patients receiving organ support …

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Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19

Simin Aysel Florescu, Dragos Stanciu, Mihaela Florentina Zaharia, Alma Gabriela Kosa et autres

IMPORTANCE: Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective: To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS: …

Teachers as Designers of Digital Educational Resources for Creative Mathematical Thinking

Chronis Kynigos, Angeliki Kolovou

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Addressing Creativity in the Collaborative Design of Digital Books for Environmental and Math Education

Maria Daskolia, Chronis Kynigos, Angeliki Kolovou

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Teachers designing e-books to foster creative mathematical thinking: the case of curvature

Angeliki Kolovou, Chronis Kynigos

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Social Creativity in the Design of Digital Resources Interweaving Math with Environmental Education - The Case Study of the Climate Change C-Book

Maria Daskolia, Angeliki Kolovou, Chronis Kynigos

This study focuses on how social creativity is manifested in the collective design of digital educational resources (called “c-books”, c for creativity) aiming to foster students’ creative mathematical thinking. We investigate social creativity as a process by focusing on the boundary-crossing encounters …

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Primary school students’ strategies in early algebra problem solving supported by an online game

Marja van den Heuvel‐Panhuizen, Angeliki Kolovou, Alexander Robitzsch

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An Intervention Including an Online Game to Improve Grade 6 Students' Performance in Early Algebra

Angeliki Kolovou, Marja van den Heuvel‐Panhuizen, Olaf Köller

This study investigated whether an intervention including an online game contributed to 236 Grade 6 students' performance in early algebra, that is, solving problems with covarying quantities. An exploratory quasi-experimental study was conducted with a pretest-posttest-control-group design. Students in the experimental group …

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Teachers’ problem-solving activity as a support for reconceptualizing their pedagogical reasoning in teaching multiplication

Ada Boufi, Angeliki Kolovou, Kpe Koeno Gravemeijer

Mathematical problem solving in primary school

Angeliki Kolovou

A student is engaged in (non-routine) problem solving when there is no clear pathway to the solution. In contrast to routine problems, non-routine ones cannot be solved through the direct application of a standard procedure. Consider the following problem: In a quiz …