Accès ouvert
2026
article
OpenAlex
Tengfei Wang, Fengdan Xu, Hui Shi, Rui Long et autres
) and MLE12 cells, we analyzed TFEB LLPS via FRAP, fusion, and in vitro phase separation assays. ITA-TFEB binding was evaluated by surface plasmon resonance (SPR). Autophagic/mitophagic flux and apoptosis were assessed, and the necessity of TFEB was validated using shRNA knockdown …
cn
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Accès ouvert
2026
article
OpenAlex
Shimei Lu, Rui Long, Yanmin Li, Fengqiong Tan et autres
ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates. Although breast milk has been identified to decrease the incidence and mortality rates associated with sepsis, the specific protective components remain unclear. In our research, milk‐derived antimicrobial …
cn
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Accès ouvert
2026
article
OpenAlex
Fengdan Xu, Y H Liu, Q Zhang, Ruying Tang et autres
Plant-derived extracellular vesicles (PDEVs) have attracted considerable attention as natural drug delivery vehicles owing to their low immunogenicity, excellent biocompatibility, cross-kingdom delivery capability and intrinsic targeting properties. They naturally encapsulate a variety of bioactive components that can synergize with loaded drugs, while …
cn
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Accès ouvert
2025
article
OpenAlex
Fengdan Xu, Qiling Zhang, Yuling Liu, Ruying Tang et autres
Chronic refractory wounds (CRWs) represent a common and challenging issue in clinical practice, including diabetic foot ulcers, pressure ulcers, venous ulcers, and arterial ulcers. These wounds significantly impact patients' quality of life and may lead to severe consequences such as amputation. Their …
cn
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Accès ouvert
2024
article
OpenAlex
Zhanghua Yin, Jintong Tan, Huafei Huang, Jianyuan Zhao et autres
BACKGROUND: Antibiotic resistance is a serious global public health issue. However, there are few reports on trends in antimicrobial susceptibility in Chinese neonates, and most of the existing evidence has been derived from adult studies. We aimed to assess the trends in …
cn
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Accès ouvert
2023
article
OpenAlex
Baihe Li, Xu Chen, Weihui Ma, Ning Li et autres
Background: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in preterm infants and lacks effective treatment. We aim to reveal the relationship between amniotic fluid (AF) peptides and lung development by analyzing the differences in the composition of AF peptides …
cn
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Accès ouvert
2022
article
OpenAlex
Fengdan Xu, Yabo Mei, Yaozhong Zhang, Qin Chen et autres
Background: The chronic lung condition known as bronchopulmonary dysplasia (BPD), which primarily affects newborns, especially preterm neonates, is brought on by prolonged oxygen consumption and mechanical ventilation. This case-control study sought to investigate the pathogenesis of BPD in preterm neonates by RNA …
cn
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