Talal A. Zari

Protective Effect of Pumpkin Seed Oil Extract Against Hepatorenal Toxicity of Thioacetamide in Male Rats

MAHMOUD E. EL-NAGGAR, Talal A. Zari

With the increasing prevalence of thioacetamide (TAA)-induced toxicity affecting human hepatorenal organs, exploring alternative therapeutic drugs with antioxidant properties is essential for safeguarding human health. This study examined the protective effect of Pumpkin seed oil (PSO, Cucurbita pepo) supplementation against TAA-induced toxicity …

sa, Égypte (code pays fourni par la source)

Retraction notice to “Phytochemical screening, HPLC fingerprinting and in vitro assessment of therapeutic potentials of different apricot cultivars against diabetes, Alzheimer's disease and cancer” [Heliyon 10 (2024) e38673]

Zahid Nabi Sheikh, Vikas Kumar Sharma, Shilpa Raina, Parshant Bakshi et autres

[This retracts the article DOI: 10.1016/j.heliyon.2024.e38673.].

in, sa, bd (code pays fourni par la source)

RETRACTED: Phytochemical screening, HPLC fingerprinting and in vitro assessment of therapeutic potentials of different apricot cultivars against diabetes, Alzheimer's disease and cancer

Zahid Nabi Sheikh, Vikas Sharma, Shilpa Raina, Rizwan Yousuf et autres

) cultivars. High-performance liquid chromatography (HPLC) was utilized to determine the concentrations of bioactive compounds across 10 distinct apricot cultivars. Initial phytochemical screening revealed a significant content of secondary metabolites. Subsequently, methanolic extracts from these cultivars were evaluated for their therapeutic potential …

in, sa, bd (code pays fourni par la source)

Investigation and drug design for novel molecules from natural products as inhibitors for controlling multiple myeloma disease using in-silico tools

Ali Zari, Lina A. F. Kurdi, Fatima A. Jaber, Khalid M. S. Al-Ghamdi et autres

Multiple myeloma (MM) is a disease that causes plasma cell growth in the bone marrow and immune globulin buildup in blood and urine. Despite recent advances in MM therapy, many still die due to its high mortality rate. A study using computational …

sa, Égypte, bd, ae (code pays fourni par la source)

Unveiling Phytoconstituents with Inhibitory Potential Against Tyrosine-Protein Kinase Fyn: A Comprehensive Virtual Screening Approach Targeting Alzheimer’s Disease

Mohammed Alrouji, Taghreed A. Majrashi, Fahad Abdulrahman Alhumaydhi, Ali Zari et autres

BACKGROUND: Tyrosine-protein kinase Fyn (Fyn) is a critical signaling molecule involved in various cellular processes, including neuronal development, synaptic plasticity, and disease pathogenesis. Dysregulation of Fyn kinase has been implicated in various complex diseases, including neurodegenerative disorders such as Alzheimer's and Parkinson's …

sa, ae, in (code pays fourni par la source)

Molecular and Phytochemical Characterizations of Cichorium intybus L. in Diverse Ecogeographical Regions of Kashmir Himalaya

Bisma Malik, Fayaz Ahmad Dar, Tanveer Bilal Pirzadah, Ali Zari et autres

Cichorium intybus L. (chicory) is an important medicinal plant with significant economic potential and has recently gained rapid momentum in the functional food sector. In the present study, soil chemistry, phytochemical, and molecular diversity were assessed for 50 accessions of chicory collected …

in, sa, bd (code pays fourni par la source)

Pharmacophore-based virtual screening approaches to identify novel molecular candidates against EGFR through comprehensive computational approaches and in-vitro studies

Firoz A. Dain Md Opo, Mohammed Moulay, Ali Zari, Afnan Alqaderi et autres

Alterations to the EGFR (epidermal growth factor receptor) gene, which primarily occur in the axon 18–21 position, have been linked to a variety of cancers, including ovarian, breast, colon, and lung cancer. The use of TK inhibitors (gefitinib, erlotinib, lapatinib, and afatinib) …

sa, Algérie, bd, Égypte, qa (code pays fourni par la source)

Studies on Sexual Reproduction of Two Reef Building Corals Seriatopora hystrix and Lobophyllia corymbosa in the Jeddah Coast of Red Sea

Yahya A. M. Floos, Abdulmohsin Al-Sofyani, Talal A. Zari

In Sharm Ubhur, the sexual reproduction of the scleractinian corals Seriatopora hystrix and Lobophyllia corymbosa was investigated for a year. S. hystrix is hermaphrodite brooders with internal fertilization and larvae development within their polyps, according to the researchers. The L. corymbosa, on …

sa (code pays fourni par la source)

Anticancer Activity of Cordia dichotoma against a Panel of Human Cancer Cell Lines and Their Phytochemical Profiling via HPLC and GCMS

Shilpa Raina, Vikas Kumar Sharma, Zahid Nabi Sheikh, Navneet Kour et autres

(bark, leaves, pulp and seed). The plant material was collected from UT of J&K and methodical bioassays were carried out on ten human cancer cell lines (Michigan Cancer Foundation-7 (MCF-7), M.D. Anderson-Metastatic Breast (MDA-MB-231), Neuroblastoma-2a (N2A), SH-SY5Y, U-251, HCT-116, SW-620, A-549, MIA …

in, sa, bd (code pays fourni par la source)

Anticancer Properties of Eugenol: A Review

Ali T. Zari, Talal A. Zari, Khalid Rehman Hakeem

Conventional cancer treatments have shown several unfavourable adverse effects, as well as an increase in anticancer drug resistance, which worsens the impending cancer therapy. Thus, the emphasis is currently en route for natural products. There is currently great interest in the natural …

sa (code pays fourni par la source)

Effects of Caralluma russeliana stem extract on some physiological parameters in streptozotocin-induced diabetic male rats

Talal A. Zari, Mesfer A. Al-Thebaiti

Purpose: The aim of this study was to investigate the effects of Caralluma russeliana stem extract on some physiological parameters in streptozotocin induced diabetes in male Wistar rats after 8 weeks. Materials and methods: The experimental rats were randomly assigned into four …

sa (code pays fourni par la source)

Effects of Caralluma russeliana stem extract on some physiological parameters in streptozotocin-induced diabetic male rats

Talal A. Zari, Al-Thebaiti MA

Talal A Zari, Mesfer A Al-Thebaiti Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia Purpose: The aim of this study was to investigate the effects of Caralluma russeliana stem extract on some physiological parameters in streptozotocin induced …