Thomas Kissel

Injectable Biodegradable Microspheres for Vaccine Delivery

Thomas Kissel, Regina Koneberg

Immunization against infectious diseases has saved innumerable lives and contributed significantly to today’s increased life expectancy. In spite of these impressive results, there is still considerable potential for improved vaccines. Biodegradable delivery systems for vaccines that are administered by a parenteral application …

Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery

Olivia M. Merkel, Leigh Matthew Marsh, Holger Garn, Thomas Kissel

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Influence of amine-modified poly(vinyl alcohol)s on vibrating-membrane nebulizer performance and lung toxicity

Moritz Beck‐Broichsitter, Olga V. Samsonova, Juliane Nguyen, Thomas Schmehl et autres

de, us (code pays fourni par la source)

Potential of the isolated lung technique for the examination of sildenafil absorption from lung-delivered poly(lactide- co -glycolide) microparticles

Moritz Beck‐Broichsitter, Katharina Stoisiek, Adam Bohr, Letícia Aragão Santiago et autres

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Formulation and process considerations for the design of sildenafil-loaded polymeric microparticles by vibrational spray-drying

Moritz Beck‐Broichsitter, Adam Bohr, Letícia Aragão Santiago, Andreas Klingl et autres

CONTEXT AND OBJECTIVE: The current study reports the preparation and characterization of sildenafil-loaded poly(lactide-co-glycolide) (PLGA)-based microparticles (MPs) by means of vibrational spray-drying. Emphasis was placed on relevant formulation and process parameters with influence on the properties of obtained powders. Materials and methods, …

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Efficient and Tumor Targeted siRNA Delivery by Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate (PEI–PCL–PEG–Fol)

Li Liu, Mengyao Zheng, Damiano Librizzi, Thomas Renette et autres

Efficient delivery of functional nucleic acids into specific cells or tissues is still a challenge for gene therapy and largely depends on targeted delivery strategies. The folate receptor (FR) is known to be overexpressed extracellularly on a variety of human cancers and …

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Layer-by-layer nanostructured protein loaded nanoparticles: A feasibility study using lysozyme as model protein and chitosan as coating material

Cuifang Cai, Shirui Mao, Thomas Kissel

cn, de (code pays fourni par la source)

Prolonged vasodilatory response to nanoencapsulated sildenafil in pulmonary hypertension

Moritz Beck‐Broichsitter, Andreas Hecker, Djuro Kosanovic, Thomas Schmehl et autres

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Direct fractionation of spray-dried polymeric microparticles by inertial impaction

Moritz Beck‐Broichsitter, Boris Strehlow, Thomas Kissel

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Modified vibrating-mesh nozzles for advanced spray-drying applications

Moritz Beck‐Broichsitter, Ilka E. Paulus, Andreas Greiner, Thomas Kissel

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Biodegradable capsules as non-viral vectors for in vitro delivery of PEI/siRNA polyplexes for efficient gene silencing

Carolin Ganas, Annika Weiß, Moritz Nazarenus, Susanne Rösler et autres

de (code pays fourni par la source)

Back Cover: Macromol. Biosci. 8/2014

Markus Hellmund, Haixia Zhou, Olga V. Samsonova, Pia Welker et autres

Back Cover: Polymerization of the monomers glycerol and GTGE via mini emulsion is shown to form polyglycerol based nanogels with a defi ned size of ≈100 nm by R. Haag and co-workers. On page 1215, these nanogels are functionalized with a varying …

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