Salvador Uribe‐Carvajal

In Saccharomyces cerevisiae ΔRIB1 and ΔRIB4 mutants, riboflavin auxotrophy is reverted by Wolbachia (wStr) infection

Ofelia A. Méndez-Romero, Carolina Ricardez-García, Salvador Uribe‐Carvajal

In endosymbiosis, unicellular organisms, mostly prokaryotes, live inside the cells of a host that may be uni- or multicellular. More than half insect and arthropod species host the obligate endosymbiont Wolbachia spp., an alpha-proteobacterium that, given time, may coevolve with its host …

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An Exploratory Study on Two Exogenous Estrogenic Metabolites (EDMs): Their Effects In Vitro and on Oophorectomized Female Rats

Alejandro Silva‐Palacios, Gabriela Navarrete-Anastasio, Elizabeth Lira‐Silva, Leonardo del Valle‐Mondragón et autres

Background: For a long time, it was thought that estrogen degradation metabolites (EDMs) had no role in the female body, but this view has changed. Despite the progress, there are still unknowns about EDMs and the heart. We found that EDMs affect …

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Antiplatelet activity of novel aminoestrogens: R-β-mefenetame as a candidate for safer estrogen-based therapies

Esbeidy García-Flores, Benny Giovanni Cazarín-Santos, Simón Hernández‐Ortega, Juan M. Fernández -G et autres

Hormone replacement therapy (HRT) relieves menopausal symptoms and improves quality of life. Also, estrogen-based regimens are needed for feminizing gender-affirming hormone therapy (GAHT). However, estrogen therapies may evoke thrombotic complications, and thus, modified estrogens that preserve desirable estrogenic actions, while minimizing thrombogenic …

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RNA-seq analysis of wild-type and mutated TBPL1 gene in breast cancer cells lines through CRISPR/Cas9 approach reveals novel molecular signatures

Rabia Mishal, Jorge Meléndez-Zajgla, Bertha Rueda-Zarazúa, María Luisa Labra‐Barrios et autres

Breast cancer is the leading cause of death among women globally. Several genes have been found to be transcriptionally dysregulated in cancer, according to recent studies. TATA-box binding protein (TBP) and its two paralogs, TBPL1 and TBPL2, play roles in human transcription. …

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Estrogen Degradation Metabolites: Some Effects on Heart Mitochondria

Cristina Uribe‐Alvarez, Elizabeth Lira‐Silva, Lilia Morales‐García, Natalia Chiquete‐Félix et autres

Mitochondria play crucial roles in various cellular functions, including ATP production, apoptosis, and calcium homeostasis. Signaling pathways and hormones such as estrogens regulate the mitochondrial network through genetic, epigenetic, and metabolic processes. Estrogens increase the efficiency of mitochondrial oxidative phosphorylation by preventing …

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BPS2025 - Chronological aging regulation in Rhodotorula mucilaginosa, an extremophile yeast

Carolina Ricardez García, Natalia Chiquete Félix, Ofelia A. Mendez Romero, Paola I. Acosta Valdelamar et autres

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BPS2025 - During oxidative metabolism, Rhodotorula mucilaginosa overexpresses a mitochondrion-associated cytosolic fumarate reductase (FR)

Natalia Chiquete Félix, Carolina Ricardez García, Ofelia A. Mendez Romero, Paola Acosta Valdelamar et autres

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A New Real-Time Simple Method to Measure the Endogenous Nitrate Reductase Activity (Nar) in Paracoccus denitrificans and Other Denitrifying Bacteria

José J. García‐Trejo, Sharon Rojas-Alcantar, Monserrat Alonso-Vargas, Raquel Ortega et autres

The transmembrane nitrate reductase (Nar) is the first enzyme in the dissimilatory alternate anaerobic nitrate respiratory chain in denitrifying bacteria. To date, there has been no real-time method to determine its specific activity embedded in its native membrane; here, we describe such …

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In Rhodotorula mucilaginosa, active oxidative metabolism increases carotenoids to inactivate excess reactive oxygen species

Edson Mosqueda-Martínez, Natalia Chiquete‐Félix, Paulina Castañeda-Támez, Carolina Ricardez-García et autres

Carotenoids produced by bacteria, yeasts, algae and plants inactivate Free Radicals (FR). However, FR may inactivate carotenoids and even turn them into free radicals. Oxidative metabolism is a source of the highly motile Reactive Oxygen Species (ROS). To evaluate carotenoid interactions with …

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Tissue-specific behaviour differences in the Mitochondrial Permeability Transition Pore. Liver versus Heart Mitochondria

Carolina Ricardez-García, Mauricio Reyes‐Becerril, Ofelia A. Méndez-Romero, Salvador Uribe‐Carvajal

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Exploring Wolbachia spp. infection in Drosophila melanogaster

Ofelia A. Méndez-Romero, Edson Mosqueda-Martínez, Carolina Ricardez-García, Natalia Chiquete‐Félix et autres

As stress responses, the extremophile yeast Rhodotorula mucilaginosa, expresses a highly branched respiratory chain and increases carotenoid synthesis

Salvador Uribe‐Carvajal, Paola Acosta-Valdelamar, Paulina Castañeda-Támez, Ofelia A. Méndez-Romero et autres

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