Accès ouvert
2026
article
OpenAlex
Qingbo Wang, Qingze Zeng, Kaicheng Li, Qingyan Chen et autres
Ependymomas are uncommon tumors arising from ependymal cells of the central nervous system, with lipomatous metaplasia representing an extremely rare pathological variant. We report a case of a 28-year-old male who presented with a 5-year history of an incidentally discovered intracranial mass …
cn
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Accès ouvert
2026
article
OpenAlex
Xiaopei Xu, Jiahui He, Mengting Zhou, Xiao Wu et autres
BACKGROUND: Chronic migraine (CM) imposes a significant disease burden and frequently co-occurs with medication-overuse headache (MOH). MOH is a secondary headache disorder occurring especially in individuals with primary migraine and associated with excessive analgesic use. Impaired iron homeostasis may be related to …
cn
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Accès ouvert
2026
article
OpenAlex
Ke Wang, Bo Shao, Qingze Zeng, Xiaocao Liu et autres
The atrophy of the hippocampus and its subfields represents a critical hallmark of neurodegeneration in Alzheimer's Disease (AD). However, the trajectories of stratum radiatum, lacunosum, and moleculare (SRLM) integrity along the AD continuum are still unclear. This study encompassed 178 amyloid-negative cognitively …
cn
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Accès ouvert
2025
article
OpenAlex
Yao Zhang, Xiao Luo, Hui Hong, Ruiting Zhang et autres
Abstract INTRODUCTION The contribution of cerebrovascular hemodynamic disturbances to Alzheimer's disease (AD) remains unclear. Using time‐shift analysis of blood‐oxygenation‐level‐dependent (BOLD) signals, we explored associations between cerebral blood transit time, amyloid beta (Aβ) pathology, and cognition. METHODS We included 131 non‐demented individuals from …
cn
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Accès ouvert
2025
article
OpenAlex
Kaicheng Li, Wei Ping Qian, Shuyue Wang, Zhe Sun et autres
BACKGROUND: Choroid plexus (ChP) is responsible for producing cerebrospinal fluid, which is increasingly recognized as important in the context of aging and Alzheimer’ disease (AD). However, structural alteration (especially cystic alteration) of ChP across the pathologically confirmed AD continuum remains unclear. MATERIALS …
cn, us
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2025
article
OpenAlex
Qingze Zeng, Siyan Zhong, Shaoping Nie, Ruiting Zhang et autres
BACKGROUND AND OBJECTIVES: The choroid plexus (ChP) plays a crucial role in maintaining brain health. Alzheimer disease (AD) pathologies may damage the ChP and accelerate neurodegeneration. Previous imaging studies have found overall increased ChP volume in patients with AD. In this study, …
cn
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2025
article
OpenAlex
Xiao Luo, Hui Hong, Shuyue Wang, Kaicheng Li et autres
BackgroundCerebrospinal fluid (CSF) dynamics plays a key role in clearing soluble amyloid-β from the brain, which may impact Alzheimer's disease (AD) onset.ObjectiveThis study seeks to differentiate cerebrospinal fluid dysfunction between early-onset AD (EOAD) and late-onset AD (LOAD) subtypes and to examine their …
cn
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Accès ouvert
2025
article
OpenAlex
Xiao Luo, Qingze Zeng, Kaicheng Li, Yi Chen et autres
Background Smoking, a modifiable risk factor for Alzheimer's disease (AD), is associated with impaired functional connectivity in resting-state networks (RSNs). This study investigates how smoking affects brain effective connectivity (EC). Objective Investigate smoking-associated EC alterations. Methods We identified 129 cognitively unimpaired (CU: …
cn
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Accès ouvert
2022
article
OpenAlex
Fudong Li, Z.D. Tong, Yu‐Ling Chang, Kaicheng Li et autres
OBJECTIVES: To evaluate the longitudinal association of eggs consumption with cognitive function in Chinese elderly. DESIGN: Prospective cohort study. PARTICIPANTS: 9028 participants aged ≥60 years from Zhejiang Ageing and Health Cohort Study without cognitive impairment at baseline survey. MEASUREMENTS: Cognitive function was …
cn
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