Accès ouvert
2026
article
OpenAlex
Daiqin Luo, Xianhuai Jin, Shuai Zhang, Xianlin Zeng et autres
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential and resistance to conventional therapies, representing a significant clinical challenge. Although nano albumin-bound paclitaxel (nab-PTX) has demonstrated generally good treatment effect, the mechanisms underlying its …
cn, ro, gb
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Accès ouvert
2025
article
OpenAlex
Yong Sun, Yi Cui, Daiqin Luo, Chuan Tian
Glutamine, recognized as a conditionally essential amino acid, plays a crucial role in cellular metabolism and significantly impacts the tumor microenvironment. Recent studies show that glutamine metabolism directly influences the growth and survival of hepatocellular carcinoma (HCC) cells. Recent research demonstrates that …
cn
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Accès ouvert
2025
article
OpenAlex
Yongxia Li, Yong Li, Taolang Li, Mingyuan He et autres
Background: This study aimed to evaluate the efficacy and safety of pyrotinib in the treatment of HER2-positive breast cancer patients with and without liver metastasis. Methods: A retrospective analysis was conducted on 91 patients with HER2-positive advanced breast cancer, who were treated …
cn
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Accès ouvert
2024
article
OpenAlex
Xianlin Zeng, Daiqin Luo, Shuai Zhang, Zhonghui Cui et autres
Radiotherapy is a commonly used method in the treatment of bladder cancers (BC). Radiation-induced immunogenic cell death (ICD) is related to the immune response against cancers and their prognoses. Even though dendritic cells (DC) act as powerful antigen-presenting cells in the body, …
cn
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Accès ouvert
2023
article
OpenAlex
Shuling Zhang, Yuanmei Wang, Daiqin Luo, Zhimei Cheng et autres
Metastasis is an important contributor to increased mortality rates in non-small cell lung cancer (NSCLC). The TGF-β signalling pathway plays a crucial role in facilitating tumour metastasis through epithelial-mesenchymal transition (EMT). Glycolysis, a key metabolic process, is strongly correlated with NSCLC metastasis. …
cn
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Accès ouvert
2023
preprint
OpenAlex
Yongxia Li, Yong Li, Taolang Li, Mingyuan He et autres
Abstract Purpose The incidence of breast cancer ranks first among female malignancies that affect women's health. Human epidermal growth factor 2 (HER2) positive breast cancer accounts for 20% − 30% of the invasive breast cancer, which is related to the poor prognosis …
cn
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Accès ouvert
2023
article
OpenAlex
Daiqin Luo, Xianlin Zeng, Shuling Zhang, LI Dao-hong et autres
Among breast cancer patients, metastases are the leading cause of death. Despite decades of effort, little progress has been made to improve the treatment of breast cancer metastases, especially triple-negative breast cancer (TNBC). The extracellular matrix plays an important role in tumour …
cn
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Accès ouvert
2022
article
OpenAlex
Zhiyong Shen, Dong Xue, Kun Wang, Facai Zhang et autres
BACKGROUND: To observe and explore the effect of metformin on the migration and proliferation of bladder cancer T24 and 5637 cells in vitro. METHODS: Bladder cancer T24 and 5637 cell lines were cultured in vitro, and were divided into group A (blank …
cn
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Accès ouvert
2021
preprint
OpenAlex
Xianlin Zeng, Zhonghui Cui, Yun Wang, Jin Chen et autres
Abstract Purpose Radiotherapy is a commonly used method in the treatment of bladder cancer (BC). Radiation induced immunogenic death (ID) and antitumor immune response are related to the prognosis of radiotherapy. As the most powerful antigen-presenting cell in the body, the role …
cn
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Accès ouvert
2021
preprint
OpenAlex
Zhiyong Shen, Dong Xue, Kun Wang, Facai Zhang et autres
Abstract Background To observe and explore the effect of metformin on the migration,and proliferation of bladder cancer T24 and 5637 cells in vitro.Methods Bladder cancer T24 and 5637 cell lines were cultured in vitro, and were divided into group A (blank control …
tw, cn
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Accès ouvert
2021
article
OpenAlex
Yongxia Li, Jianying Chang, Mingyuan He, Heran Wang et autres
Introduction. Stage IIB cervical cancer (CC) is an advanced stage CC with poor prognosis. Inflammatory response plays a crucial role in the development of CC, and systemic inflammatory indexes were related to the prognosis in several cancers. The objective of the study …
cn
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2021
article
OpenAlex
Daiqin Luo, Xinjun Wang, Xiaomei Zhong, Jianying Chang et autres
BACKGROUND: Metformin (MET) is a well-known anti-diabetic drug that also has anti-cancer effects. However, high therapeutic doses of MET on cancer cells and the low efficacy of combinatory therapeutic approaches limit its clinical application. Recent studies have shown that chrysin (CHR) can …
cn
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