Xiaofei Shi

IL-18 drives the Bhlhe40-mediated pathogenic Th17 cell response and exacerbates autoimmune disease progression

Yuan Yan Tang, Yue Zhao, Zixiang Chen, Xiaofei Shi et autres

hk, cn, fr (code pays fourni par la source)

Contribution of Interleukin-1 Receptor-Associated Kinase 1 Gene Polymorphism to Systemic Lupus Erythematosus in Chinese Patients

Lili Zhao, Wenqi Xu, Shushu Du, Feng-Yu Xi et autres

Introduction: Systemic lupus erythematosus (SLE) is a complex autoimmune condition distinguished by a wide range of clinical manifestations and numerous genetic predisposition factors. The aim of the current study was to analyze the association between the IRAK1 polymorphisms (rs3027898 and rs1059702) and …

cn (code pays fourni par la source)

Comparison of the efficacy and safety of methotrexate injection and methotrexate tablets in active RA

Qiao Lin, Jiankang Hu, Daming Ou, Xiaofei Shi et autres

OBJECTIVES: This study aimed to compare the efficacy and safety of subcutaneous MTX (SC MTX) and oral MTX (OR MTX) in treating Chinese patients with active RA. METHODS: This study included patients with active RA in China. All patients were randomly assigned …

gb, cn, us (code pays fourni par la source)

Ivarmacitinib, a selective Janus kinase 1 inhibitor, in patients with moderate-to-severe active rheumatoid arthritis and inadequate response to conventional synthetic DMARDs: results from a phase III randomised clinical trial

Jinjing Liu, Ying Jiang, Shangzhu Zhang, Shengyun Liu et autres

cn (code pays fourni par la source)

The Prospective Registry of MyositIS (PROMIS): Temporal Shifts in Causes of Death Among Patients with Idiopathic Inflammatory Myopathies

Liying Peng, Shangyi Jin, Chanyuan Wu, Xinwang Duan et autres

cn (code pays fourni par la source)

Microglial Mayhem NLRP3 Inflammasome's Role in Multiple Sclerosis Pathology

Hua Fan, Qizhi Fu, Ganqin Du, Qin Ling et autres

INTRODUCTION: This review delves into the intricate relationship between NLR inflammasomes, particularly the NLRP3 inflammasome, and the immune-mediated neurodegenerative disease, multiple sclerosis (MS). While the precise etiology of MS remains elusive, compelling research underscores the pivotal role of the immune response in …

cn (code pays fourni par la source)

Dysregulation of iron transport-related biomarkers in blood leukocytes is associated with poor prognosis of early trauma

Zhusheng Feng, Yingnan Fan, Xiaofei Shi, Xu Luo et autres

Objective: The early targeted and effective diagnosis and treatment of severe trauma are crucial for patients' outcomes. Blood leukocytes act as significant effectors during the initial inflammation and activation of innate immunity in trauma. This study aims to identify hub genes related …

cn (code pays fourni par la source)

B cell activation and autoantibody production in autoimmune diseases

Wenbo Sun, Can Zhu, Yuxin Li, Xinfeng Wu et autres

cn (code pays fourni par la source)

Systemic lupus erythematosus combined with Castleman disease and secondary paraneoplastic pemphigus: a case report

Xin Ma, Jiyuan Li, Linlin Fan, Hongwei� Jiang et autres

BACKGROUND: The literature describes a case of systemic lupus erythematosus (SLE) complicated with Castleman's disease (CD) and secondary paraneoplastic pemphigus (PNP). CASE PRESENTATION: A 12-year-old female presented with a neck mass, rash, arthralgia, and skin and mouth ulceration for 5 years were …

cn (code pays fourni par la source)

Neuroprotective Effects of Sinomenine on Experimental Autoimmune Encephalomyelitis via Anti-Inflammatory and Nrf2-Dependent Anti-Oxidative Stress Activity

Hua Fan, Yang Yang, Qianqian Bai, Dongmei Wang et autres

cn (code pays fourni par la source)

The key roles of reactive oxygen species in microglial inflammatory activation: Regulation by endogenous antioxidant system and exogenous sulfur-containing compounds

Hua Fan, Qianqian Bai, Yang Yang, Xiaofei Shi et autres

cn (code pays fourni par la source)

Correction: A multi-center, open-label, randomized study to explore efficacy and safety of baricitinib in active primary Sjogren’s syndrome patients

Wei Bai, Fan Yang, Huji Xu, Wei Wei et autres

gb, cn, us (code pays fourni par la source)