Igor A. Popov

Beyond the convergence of metabolic reprogramming in primary liver cancer: a comprehensive review on energy and lipids metabolism

Galina S. Stupnikova, Igor A. Popov, Stanislav I. Pekov

Hepatocellular carcinoma and cholangiocarcinoma, the most common primary liver cancers, are usually considered quite different pathologies. However, convergent metabolic reprogramming across different progenitor cells can result in similar molecular alterations and, even in a combined form of cancer that is characterized by …

ru (code pays fourni par la source)

Dynamics of Postmortem Gene Expression in Normal and Neoplastic Murine Liver

Evgeny E. Buyko, Ekaterina A. Perina, Danil S. Sobakin, Matvey M. Tsyganov et autres

The use of postmortem (autopsy) material in fundamental and applied biomedical research significantly facilitates the collection of biomaterial for statistically robust sample cohorts. However, natural adaptive processes to developing cellular stress in the early postmortem period, caused by oxygen and nutrient deprivation, …

ru (code pays fourni par la source)

CARE OF AN EXTENSIVE LONG-TERM NON-HEALING WOUND OF THE ANKLE JOINT AND FOOT WITHOUT SYSTEMIC ANTIBIOTICS

O. G. Sarkisyan, Andrey N. Surkov, И. И. Бабич, N. Parhomina et autres

Purulent pathology accounts for more than 70% of the structure of surgical diseases, while purulent inflammatory processes of soft tissues make up a significant proportion of it, and the most often recommended treatment method is antibacterial therapy. However, currently the primary care …

ru (code pays fourni par la source)

Development of a Device for Conservative Treatment of Diabetic Foot Syndrome

D. V. Belik, V. D. Belik, V.А. Drobyshev, A. E. Polishchuk et autres

This article describes a device for the conservative treatment of diabetic foot syndrome. The device exposes the patient's foot structures to a traveling magnetic field, an ultra-high frequency electric field, ultraviolet radiation, and infrared laser radiation. The purpose of this multi-modal approach …

ru (code pays fourni par la source)

Topological segmentation of mass spectrometry imaging data

Maria M. Derkach, Anatoly Sorokin, Andrey A. Kuzin, Е. Н. Николаев et autres

Introduction: Image segmentation is an important challenge in mass spectrometry imaging data processing. Here, we report an unsupervised topological segmentation method adapted to the specific nature of mass spectrometry data. Unlike machine learning clustering algorithms, the proposed method retains the physical and …

ru (code pays fourni par la source)

Algorithm for Selecting Organic Compounds to Verify the Resolution of Electron Ionization Mass Spectrometers

В. Г. Ткаченко, Sergey V. Silkin, Vasily A. Eliferov, Denis V. Kolesnik et autres

The ion coalescence phenomenon complicates the evaluation of the effective resolution of Fouriertransform mass spectrometers.We propose an approach for confirming the resolution of an electron ionization Fourier-transform mass spectrometer using pairs of organic substances identified by automatically generated formula differences.The proposed method …

ru (code pays fourni par la source)

Tight Integration of Vision/Radar with INS/GNSS for Reliable Navigation in Autonomous Applications

Dylan Krupity, Noah Giustini, Igor A. Popov, Parham Nooralishahi et autres

The fusion of data from different sensors makes localization more accurate and reliable. A common method is to integrate perception sensors with navigation systems to improve position estimates. The addition of perception sensors helps reduce the limitations of other technologies, such as …

Bile Acid Profiling for Differential Diagnosis of Hepatobiliary Cancers and Cholelitiasis

Galina S. Stupnikova, Andrey D. Dolbnya, Andrey A. Kuzin, Igor A. Popov et autres

Abstract Cholangiocarcinoma (CCA) and pancreatic ductal adenocarcinoma (PDAC) are malignant tumors that can be characterized by low patient survival rates. They have similar anatomical proximity, morphological similarity, and an overlapping immunohistochemical profile. Even with the aid of modern imaging techniques, it is …

ru (code pays fourni par la source)

Exploring the potential of a bioassembler for protein crystallization in space

Christopher MacCarthy, Elizaveta V. Koudan, Mikhail B. Shevtsov, Vladislav A. Parfenov et autres

Protein crystallization holds paramount significance in structural biology, serving as a pivotal technique for unveiling the three-dimensional (3D) architecture of proteins. While microgravity conditions in space offer distinct advantages for high-quality protein crystal growth by mitigating the influences of gravity and convection, …

ru (code pays fourni par la source)

Onsite Analysis of Complex Samples Using Miniature Mass Spectrometry With Direct Sampling and Ionization

Yiming Zou, Xuan Liu, Liangwei Du, Jiafan Yang et autres

RATIONALE: Miniature mass spectrometry (mini-MS) is a powerful method for onsite analysis of complex. The onsite sampling/ionization approach is critical in rapid screening of complex samples by mini-MS in field environments. Therefore, new development of direct ionization/sampling method coupled with mini-MS is …

cn, ru (code pays fourni par la source)

Opisthorchiasis and pancreatic cancer

Vladimir V. Ivanov, Т. Б. Комкова, I. A. Lyzko, Ekaterina A. Perina et autres

Chronic opisthorchiasis is recognized as a precancerous condition that can present similarly to other diseases of the hepatopancreatoduodenal zone. Statistically, there is a proven correlation between the duration and intensity of parasitic invasion and the development of carcinogenesis, with the manifestations of …

ru (code pays fourni par la source)

Author response for "Onsite Analysis of Complex Samples Using Miniature Mass Spectrometry With Direct Sampling and Ionization"

Yiming Zou, Xuan Liu, Liangwei Du, Jiafan Yang et autres