Patricia Mármol

Digital Tomosynthesis and COVID-19: An improvement in the assessment of pulmonary opacities

Inmaculada Calvo, Sara Santa-Cruz Calvo, María Gracia Aranzana, Patricia Mármol et autres

es, us (code pays fourni par la source)

Tomografía digital y COVID-19: un avance en la valoración de opacidades pulmonares

Inmaculada Calvo, Sara Santa-Cruz Calvo, María Gracia Aranzana, Patricia Mármol et autres

es, us (code pays fourni par la source)

Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Patricia Mármol, Favio Ariel Krapacher, Carlos F. Ibáñez

Adaptation to nutrient availability is crucial for survival. Upon nutritional stress, such as during prolonged fasting or cold exposure, organisms need to balance the feeding of tissues and the maintenance of body temperature. The mechanisms that regulate the adaptation of brown adipose …

se, sg, Afrique du Sud (code pays fourni par la source)

Author response: Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Patricia Mármol, Favio Ariel Krapacher, Carlos F. Ibáñez

The activin receptor ALK7 regulates the adaptation of brown adipose tissue to nutrient availability by preventing over-activation of signaling pathways induced by fasting, allowing appropriate response to cold exposure.

se, sg, Afrique du Sud (code pays fourni par la source)

Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Flow Cytometry

Irene van der Haar Àvila, Patricia Mármol, Jeannette Cany, Rolf W. Kiessling et autres

se, nl (code pays fourni par la source)

Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Chromium Release Assay

Irene van der Haar Àvila, Patricia Mármol, Rolf W. Kiessling, Yago Pico de Coaña

se, nl (code pays fourni par la source)

Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Tingqing Guo, Patricia Mármol, Annalena Moliner, Marie Björnholm et autres

Obesity is associated with blunted β-adrenoreceptor (β-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient overload to catecholamine resistance are poorly understood. We report that targeted disruption of TGF-β superfamily receptor ALK7 alleviates diet-induced catecholamine resistance in adipose …

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Author response: Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Tingqing Guo, Patricia Mármol, Annalena Moliner, Marie Björnholm et autres

Adrenaline and noradrenaline are two hormones that trigger the burst of energy and increase in heart rate and blood pressure that are needed for the ‘fight-or-flight’ response. Both belong to a group of chemicals called catecholamines. These chemicals bind to cells carrying …

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Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands

Haiya Wu, Karima Mezghenna, Patricia Mármol, Tingqing Guo et autres

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Requirement for Aralar and Its Ca2+-binding Sites in Ca2+ Signal Transduction in Mitochondria from INS-1 Clonal β-Cells

Patricia Mármol, Beatriz Pardo, Andreas Wiederkehr, Araceli del Arco et autres

Aralar, the mitochondrial aspartate-glutamate carrier present in beta-cells, is a component of the malate-aspartate NADH shuttle (MAS). MAS is activated by Ca2+ in mitochondria from tissues with aralar as the only AGC isoform with an S0.5 of approximately 300 nm. We have …

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Role of aralar, the mitochondrial transporter of aspartate‐glutamate, in brain N‐acetylaspartate formation and Ca2+ signaling in neuronal mitochondria

Jorgina Satrústegui, Laura Contreras, Milagros Ramos, Patricia Mármol et autres

Aralar, the Ca(2+)-dependent mitochondrial aspartate-glutamate carrier expressed in brain and skeletal muscle, is a member of the malate-aspartate NADH shuttle. Disrupting the gene for aralar, SLC25a12, in mice has enabled the discovery of two new roles of this carrier. On the one …

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Reduced N-Acetylaspartate Levels in Mice Lacking Aralar, a Brain- and Muscle-type Mitochondrial Aspartate-glutamate Carrier

Md. Abdul Jalil, Laila Begum, Laura Contreras, Beatriz Pardo et autres

Aralar is a mitochondrial calcium-regulated aspartate-glutamate carrier mainly distributed in brain and skeletal muscle, involved in the transport of aspartate from mitochondria to cytosol, and in the transfer of cytosolic reducing equivalents into mitochondria as a member of the malate-aspartate NADH shuttle. …

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