2024
conference-abstract
OpenAlex
Charlotte E. Spencer, Graham Ross, Thomas Mead, Amy Strange et autres
Abstract Clear cell Renal Cell Carcinoma (ccRCC) is profoundly angiogenic, characterised by complex yet heterogenous vascular networks. Blood vessels are an important constituent part of the tumour microenvironment (TME) and, in addition to immune cells, are the target of drug therapies in …
gb
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Robert Hinch, William J. M. Probert, Anel Nurtay, Michelle L. Kendall et autres
SARS-CoV-2 has spread across the world, causing high mortality and unprecedented restrictions on social and economic activity. Policymakers are assessing how best to navigate through the ongoing epidemic, with computational models being used to predict the spread of infection and assess the …
gb, us
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Bahti Zakirov, Georgios Charalambous, Raphaël Thuret, Irene M. Aspalter et autres
Abstract How do cells make efficient collective decisions during tissue morphogenesis? Humans and other organisms use feedback between movement and sensing known as ‘sensorimotor coordination’ or ‘active perception’ to inform behaviour, but active perception has not before been investigated at a cellular …
gb, us
(code pays fourni par la source)
2020
conference-paper
OpenAlex
Thomas Mead
The study of morphogenesis has increasingly entailed the use of computer simulations to predict intricate behaviours from these systems, which has led to the development of tools for computational biologists to build their own simulations. However, uptake of these tools by experimental …
gb
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Bahti Zakirov, Georgios Charalambous, Irene M. Aspalter, Kelvin Van-Vuuren et autres
Abstract How do cells make efficient collective decisions during tissue morphogenesis? Humans and other organisms utilize feedback between movement and sensing known as ‘sensorimotor coordination’ or ‘active perception’ to inform behaviour, but active perception has not before been investigated at a cellular …
gb, us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Claudia Prahst, Parham Ashrafzadeh, Thomas Mead, Ana M. Figueiredo et autres
As the general population ages, more people are affected by eye diseases, such as retinopathies. It is therefore critical to improve imaging of eye disease mouse models. Here, we demonstrate that 1) rapid, quantitative 3D and 4D (time lapse) imaging of cellular …
us, se, gb, pt
(code pays fourni par la source)
Accès ouvert
2020
peer-review
OpenAlex
Claudia Prahst, Parham Ashrafzadeh, Thomas Mead, Ana C. Figueiredo et autres
Improved 3D and 4D imaging of neurovascular processes across scales reveals new insights into eye disease mouse models and shows retinal vessels are significantly distorted using standard flat-mount confocal imaging.
se, us, gb
(code pays fourni par la source)
Accès ouvert
2019
preprint
OpenAlex
Claudia Prahst, Parham Ashrafzadeh, Kyle Harrington, Lakshmi Venkatraman et autres
Abstract As the general population ages and the incidence of diabetes increases epidemically, more people are affected by eye diseases, such as retinopathies. It is therefore critical to improve imaging of eye disease mouse models. Here, we demonstrate that 1) rapid, quantitative …
us, se, pt, gb
(code pays fourni par la source)