Antonia Pagkali

Well-differentiated liposarcomas and dedifferentiated liposarcomas: Systemic treatment options for two sibling neoplasms

Anastasios I. Kyriazoglou, Antonia Pagkali, Ioannis Kotsantis, Panagiota Economopoulou et autres

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Pathophysiological Mechanisms and Clinical Associations of Non-Alcoholic Fatty Pancreas Disease

Antonia Pagkali, Anastasios P. Makris, Kalliopi Brofidi, Aris P. Agouridis et autres

Non-Alcoholic Fatty Pancreas disease (NAFPD), characterized by fat accumulation in pancreatic tissue, is an emerging clinical entity. However, the clinical associations, the underlying molecular drivers, and the pathophysiological mechanisms of NAFPD have not yet been characterized in detail. The NAFPD spectrum not …

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High-density lipoprotein cholesterol and multiple myeloma: A systematic review and meta-analysis

Anastasios P. Makris, Antonia Pagkali, Emmanouil Nikolousis, Theodosios D. Filippatos et autres

Background and aims: To systematically investigate all relevant evidence on the association between high-density lipoprotein cholesterol (HDL-C) and multiple myeloma (MM). Methods: We searched PubMed and Cochrane library databases (up to 20 September 2022) for studies with evidence on HDL-C in patients …

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Anti-Claudin Treatments in Gastroesophageal Adenocarcinoma: Mainstream and Upcoming Strategies

Giulia Grizzi, Kostantinos Venetis, Nerina Denaro, María José Bonomi et autres

Claudins (CLDNs) are a multigene family of proteins and the principal components of tight junctions (TJs), which normally mediate cell-cell adhesion and selectively allow the paracellular flux of ions and small molecules between cells. Downregulation of claudin proteins increases the paracellular permeability …

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Safety Profile of Niraparib as Maintenance Therapy for Ovarian Cancer: A Systematic Review and Meta-Analysis

Antonia Pagkali, Ioannis Mamais, Adamantios Michalinos, Aris P. Agouridis

Background: Patients with epithelial ovarian cancer (EOC), treated with niraparib maintenance, present with haematological and gastrointestinal toxicities. Limited data exist on niraparib safety assessment. Objective: To evaluate niraparib safety profile, as maintenance therapy, in women with platinum-sensitive EOC. Methods: PubMed and Cochrane …

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High-density lipoprotein cholesterol: A marker of COVID-19 infection severity?

Aris P. Agouridis, Antonia Pagkali, Elias Zintzaras, Evangelos C. Rizos et autres

BACKGROUND AND AIMS: To systematically address all the relevant evidence of the association between high-density lipoprotein cholesterol (HDL-C) and COVID-19 infection. METHODS: We searched PubMed, PubMed Central and medRxiv databases (up to May 2021) for studies related to HDL-C and COVID-19 infection. …

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