Lissania Guerra-Calderas

Deep DNA sequencing of MGMT, TP53 and AGT in Mexican astrocytoma patients identifies an excess of genetic variants in women and a predictive biomarker

José Alberto Carlos-Escalante, Sonia Iliana Mejía‐Pérez, Ernesto Soto‐Reyes, Lissania Guerra-Calderas et autres

mx (code pays fourni par la source)

IJMS Supplementary material

Jose Alberto Carlos Escalante, Sonia IlianaMejía-Pérez, Ernesto Soto‐Reyes, Lissania Guerra-Calderas et autres

Supplementary material 1: individual patient data from the discovery cohort. Supplementary material 2: supplementary results; table S1: Prevalence of MGMT promoter methylation and MGMT variants patients from the Discovery cohort; table S2: Multivariate Cox regression model for overall survival (OS) in patients …

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Saliva is a reliable and accessible source for the detection of SARS-CoV-2

Luis A. Herrera, Alfredo Hidalgo‐Miranda, Nancy Reynoso‐Noverón, Abelardo Meneses‐García et autres

OBJECTIVES: The aim of this study was to investigate the feasibility of saliva sampling as a non-invasive and safer tool to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to compare its reproducibility and sensitivity with nasopharyngeal swab samples (NPS). The …

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Landscape of Germline Genetic Variants in AGT, MGMT, and TP53 in Mexican Adult Patients with Astrocytoma

José Alberto Carlos-Escalante, Liliana Gómez‐Flores‐Ramos, Xiaopeng Bian, Alexander Perdomo‐Pantoja et autres

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The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective

Itzel Alejandra Hernández-Romero, Lissania Guerra-Calderas, Marisol Salgado-Albarrán, Tatiana Maldonado-Huerta et autres

Angiogenesis is a crucial process for organ morphogenesis and growth during development and it is especially relevant during repair of wounded tissue in adults. It is coordinated by an equilibrium of pro- and anti-angiogenic factors; nevertheless, when affected, it promotes several diseases. …

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The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer

Marisol Salgado-Albarrán, Rodrigo González‐Barrios, Lissania Guerra-Calderas, Nicolás Alcaraz et autres

The identification of prognostic biomarkers is a priority for patients suffering from high-grade serous ovarian cancer (SOC), which accounts for >70% of ovarian cancer (OC) deaths. Meanwhile, borderline ovarian cancer (BOC) is a low malignancy tumor and usually patients undergo surgery with …

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Histamine Modulates Midbrain Dopamine Neuron Differentiation Through the Regulation of Epigenetic Marks

Fernanda Vargas-Romero, Rodrigo González‐Barrios, Lissania Guerra-Calderas, Itzel Escobedo-Ávila et autres

During midbrain development, dopamine neuron differentiation occurs before birth. Epigenetic processes such as DNA methylation and demethylation as well as post-translational modification of histones occur during neurogenesis. Here we administered histamine (HA) into the brain of E12 embryos in vivo and observed …

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Angiotensinogen rs5050 germline genetic variant as potential biomarker of poor prognosis in astrocytoma

Alexander Perdomo‐Pantoja, Sonia Iliana Mejía‐Pérez, Nancy Reynoso‐Noverón, Liliana Gómez‐Flores‐Ramos et autres

INTRODUCTION: Renin-angiotensin system (RAS) in brain cancer represents a scarcely explored field in neuro-oncology. Recently, some pre- and clinical studies have reported that RAS components play a relevant role in the development and behavior of gliomas. The angiotensinogen (AGT) rs5050 genetic variant …

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CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines

Lissania Guerra-Calderas, Rodrigo González‐Barrios, Carlos César Patiño-Morales, Nicolás Alcaraz et autres

// Lissania Guerra-Calderas 1 , Rodrigo González-Barrios 1 , Carlos César Patiño 1 , Nicolás Alcaraz 4 , Marisol Salgado-Albarrán 1 , David Cantú de León 3 , Clementina Castro Hernández 1, 2 , Yesennia Sánchez-Pérez 1 , Héctor Aquiles Maldonado-Martínez 5 …

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The role of the histone demethylase KDM4A in cancer

Lissania Guerra-Calderas, Rodrigo González‐Barrios, Luis A. Herrera, David Cantú de León et autres

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Epigenetic deregulation of BORIS and CTCF in breast cancer

Iliana Alcalá Moreno, Ernesto Soto-Reyes, Daniela Morales-Espinosa, Rodrigo González‐Barrios et autres

Results The results suggest that BORIS is abnormally overexpressed in cancer cell lines. Data showed that in the non-neoplastic cell line BORIS was found within the nucleolus, whereas in MCF7 it was only found in the nucleoplasm. CTCF localization showed no difference …

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