Nuri KARADURMUŞ

Comparison of First-Line FOLFOX versus FOLFIRI in RAS Mutant Metastatic Colorectal Cancer Patients

Alper Topal, Goncagül Akdağ, Aysegul Dumludag, Çağlar Köseoğlu et autres

disease will progress to the metastatic stage.[2][3][4] In metastatic patients, 5-year survival is less than 20%.5 For metastatic disease, the backbone of treatment is 5-fluorouracil (5-FU)-based regimens.These include 5-FU+irinotecan (FOLFIRI), capecitabine+oxaliplatin, and 5-FU+oxaliplatin (FOLFOX).6 In selected patients, triplet ABSTRACT Objective: Colorectal cancer …

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Diagnosis and Treatment of Musculoskeletal Sarcoma in a Tertiary Reference Hospital

Mustafa Aydın, Begüm Aslantaş Kaplan, Ömer Levent Karadamar, Ali Murat Başak et autres

Objective: Aim of study was to describe the clinical characteristics and short-term survival of adult patients diagnosed with skeletal Ewing sarcoma. Methods: This descriptive study included 15 patients who underwent surgical treatment after being diagnosed with skeletal Ewing sarcoma and received perioperative …

Immunotherapy for Lung Cancer

Nuri KARADURMUŞ, Nalân Akyürek, Adnan Aydıner, Recep Savaş et autres

ABS TRACT Lung cancer is one of the leading causes of cancer-related deaths in men and women.Similar to the approach with other cancer types, lung cancer staging is crucial in planning an effective treatment plan and predicting patient prognosis.Effective immunotherapies for patients …

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Unresectable Hepatocellular Carcinoma and Prognostic Factors of Sorafenib Treatment: A Real-Life Experience

Cihan EROL, Murat Bardakçı, Mutlu HIZAL, Seda Kahraman et autres

Sorafenib, a multi-kinase inhibitor agent, has been used in hepatocellular carcinoma (HCC) treatment for almost one and a half decades.It was the gold standard treatment based on two randomized Phase III trials.1,2 Sorafenib remained the only agent used in systemic therapy from …

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Clinicopathological Factors in Relation to HER2 Status in Metastatic Gastric Cancer: A Retrospective Observational Study

Mustafa Gürbüz, İzzet Doğan, Erman Akkuş, İbrahim KARADAĞ et autres

like trastuzumab, a monoclonal antibody that binds to human epidermal growth factor receptor 2 (HER2).Adding it to the chemotherapy in the treatment of HER2-positive, advanced-stage gastric adenocarcinoma patients improved survival in the Phase 3 Trastuzumab for

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Retrospective Analysis of Testicular Germ Cell Tumor Patients with Brain Metastases: A Single-Center Experience

Musa Barış AYKAN, Gül Sema Yıldıran, Ramazan Acar, Nazlıcan İĞRET et autres

Germ cell tumors (GCTs) are especially common in men between the ages of 20 and 40 years. 1 Generally, surgery and, when necessary, systemic chemotherapy are performed for treatment.It is a chemosensitive tumor.Owing to effective systemic treatment protocols, especially cisplatin-based chemotherapy protocols, …

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