Carolina Carrillo

Laparoscopic primary right omental torsion: a challenging diagnosis in acute abdomen: a case report

Jesús Eduardo Prior Rosas, Paul Robledo Madrid, Andrea C. Rodriguez, Carolina Carrillo

Omental torsion is rarely diagnosed preoperatively and often misdiagnosed with other pathologies as acute abdomen, the most common of them being acute appendicitis. The current choice for the management of omental torsion is laparoscopic surgery. We present a case of a 35-year-old …

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Mesenteric thrombosis as a clinical presentation of antiphospholipid syndrome: a case report and literature review

Jose E. Dzul, Valeria G. Sonda, Carolina Carrillo

Mesenteric thrombosis is a rare pathology that results from the obstruction of the arterial or venous system of the mesenteric circulation by a thrombus or embolus. The etiology of thrombus formation is rarely evident; the population statistically most affected by this pathology …

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A simplified molecular tool for detecting the Chagas etiological agent using a vector feces sample in field conditions

Luciana Larocca, Fabiana Stolowicz, Adrián A. Vojnov, Florencia Cano Suárez et autres

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Does a simplified algorithm and integrated HCV care model improve linkage to care, retention, and cure among people who inject drugs? A pragmatic quality improvement randomized controlled trial protocol

Stacey L. Klaman, Job Gideon Godino, Adam William Northrup, Sydney Virginia Lewis et autres

BACKGROUND: As many as 2.4 million Americans are affected by chronic Hepatitis C Virus (HCV) in the United States.In 2018, the estimated number of adults with a history of HCV infection in San Diego County was 55,354 (95% CI: 25,411-93,329). This corresponded …

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Trypanocidal activity of liposomal isotretinoin and loratadine formulations

Chantal Reigada, Fabio Augusto Digirolamo, Facundo Galceran, Melisa Sayé et autres

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Colorimetric RT-LAMP Detection of Multiple SARS-CoV-2 Variants and Lineages of Concern Direct from Nasopharyngeal Swab Samples without RNA Isolation

Santiago Werbajh, Luciana Larocca, Carolina Carrillo, Fabiana Stolowicz et autres

Since, during the Coronavirus disease 19 (COVID-19) pandemic, a large part of the human population has become infected, a rapid and simple diagnostic method has been necessary to detect its causative agent, the Severe Acute Respiratory Syndrome-related Coronavirus-2 (SARS-CoV-2), and control its …

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A Colorimetric RT-LAMP Detection of Multiple SARS-CoV-2 Variants of Concern and Lineages from Direct Nasopharyngeal Swab Samples without RNA Isolation

Santiago Werbajh, Luciana Larocca, Carolina Carrillo, Fabiana Stolowicz et autres

A large population has been infected by COVID-19 (Coronavirus disease-19) and it has been necessary a rapid and simple diagnostic method to detect the SARS-CoV-2and control its spread. We developed a colorimetric reverse transcription-loop-mediated isothermal amplification (RT-LAMP) kit that allow the detection …

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A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity

Manuel A. Llanos, Lucas N. Alberca, María D. Ruiz, María Laura Sbaraglini et autres

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A colorimetric, sensitive, rapid, and simple diagnostic kit for the HLB putative causal agent detection

Fabiana Stolowicz, Luciana Larocca, Santiago Werbajh, Yanil Parma et autres

Huanglongbing (HLB) is one of the most devastating diseases in citrus worldwide. The Gram-negative bacterial plant pathogen “Candidatus Liberibacter spp.” is phloem-limited and vectored by citrus psyllids. The species “Candidatus Liberibacter asiaticus” (C.Las) has been detected in Argentina, and its vector has …

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Broadening the spectrum of ivermectin: Its effect on Trypanosoma cruzi and related trypanosomatids

Laura Fraccaroli, María D. Ruiz, Virginia Perdomo, Agustina Nicole Clausi et autres

Chagas disease is an endemic American parasitosis, caused byTrypanosoma cruzi. The current therapies, benznidazole (BZN) and nifurtimox (NFX), show limited efficacy and multiple side effects. Thus, there is a need to develop new trypanocidal strategies. Ivermectin (IVM) is a broad-spectrum antiparasitic drug …

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The Amazonian Tropical Bites Research Initiative, a hope for resolving zoonotic neglected tropical diseases in the One Health era

Emma L. Taylor, Elsa Gladys Aguilar-Ancori, Ashley C. Banyard, Ísis Abel et autres

BACKGROUND: Neglected tropical diseases (NTDs) disproportionately affect populations living in resource-limited settings. In the Amazon basin, substantial numbers of NTDs are zoonotic, transmitted by vertebrate (dogs, bats, snakes) and invertebrate species (sand flies and triatomine insects). However, no dedicated consortia exist to …

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Towards a versatile and economic Chagas Disease point-of-care testing system, by integrating loop-mediated isothermal amplification and contactless/label-free conductivity detection

Federico Figueredo, Fabiana Stolowicz, Adrián A. Vojnov, Wendell K. T. Coltro et autres

Rapid diagnosis by using small, simple, and portable devices could represent one of the best strategies to limit the damage and contain the spread of viral, bacterial or protozoa diseases, principally when they can be transmitted by air and are highly contagious, …

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