Hyun Gi Kim

Impact of reader experience on the time-saving potential of a novel computer-aided tool for Ann Arbor staging of pediatric hodgkin lymphoma

Iryna Vasyliv, Michael Joseph Barrow, Lucia Baratto, Hyun Gi Kim et autres

Background Accurate staging of Hodgkin lymphoma in children is important for selecting appropriate therapies. However, evaluation of Ann Arbor staging criteria on whole-body 18 F-FDG PET scans is time-consuming and subject to reader-dependent variability. Objective To determine if a novel computer-aided staging …

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Perivascular space volume measurement at the inferior basal ganglia on cranial ultrasound in neonates: associations with germinal matrix hemorrhage and brain maturation

Se Won Oh, Arum Choi, Dayeon Bak, Jimin Kim et autres

PURPOSE: The aim of this study was to assess the feasibility of cranial ultrasound (CUS)-based perivascular space (PVS) volume quantification in neonates, evaluate its relationship with magnetic resonance imaging (MRI)-based PVS volume measurements, explore associations with germinal matrix hemorrhage (GMH), and examine …

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Neuroimaging evaluation of high dose methotrexate-induced neurotoxicity in pediatric and young adults: a PET/MRI study

Zahra Shokri Varniab, Hyun Gi Kim, Ricarda von Krüchten, Yashas Ullas Lokesha et autres

Introduction High-dose Methotrexate (HDMTX) can induce neurotoxicity, yet its impact on brain metabolism remains underexplored. This study aimed to assess short- and long-term brain metabolic changes post-HDMTX on 18F-FDG PET/MRI relative to baseline (pre-HDMTX) scans. Methods In this IRB approved, retrospective study, …

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Cerebellum Development in Neonates and Association With Preterm Birth: MR Fingerprinting Study

Arum Choi, Dongyeob Han, Geunhye Lee, Suhjin An et autres

Purpose: Cerebellar maturation is critical for neonatal development and is often disrupted during preterm birth.This study used magnetic resonance (MR) fingerprinting to quantify age-related cerebellar changes and determine the specific impact of prematurity. Materials and Methods:This retrospective study included 31 neonates (22 …

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Imaging Biomarkers of the Glymphatic System in the Developing Brain

Arum Choi, Junghwa Kang, Hosna Asma-ull, Yoonho Nam et autres

The glymphatic system is increasingly recognized as a brain-wide pathway that mediates cerebrospinal fluid-interstitial fluid exchange and metabolic waste clearance. However, unlike in adults, its developmental trajectory and clinical relevance during infancy and childhood remain poorly understood. This review summarizes imaging biomarkers …

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Developmental Brain Age Estimation From MRI Data: A Systematic Review of Deep Learning Approaches and Open Datasets

Hosna Asma-ull, Misha Kaandorp, András Áron Jakab, Hyun Gi Kim

Brain age is an emerging concept that reflects complex, time-dependent changes in brain structure, identifying departures from expected neurodevelopmental patterns. In the developing brain, accurate MRI-based age estimation is a quantitative biomarker for detecting atypical neurodevelopment, facilitating early diagnosis, guiding clinical decision-making, …

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Pilot study of association between neonatal brain perivascular space volume and neurodevelopmental outcomes at 24 months

Arum Choi, Ah‐Ra Cho, Hosna Asma-ull, Yoonho Nam et autres

INTRODUCTION: Perivascular space (PVS) has recently gained attention as a neurological indicator. However, there is still limited research on the relationship between basal ganglia PVS (BG-PVS) volume and neurodevelopmental outcome of neonates. Therefore, this pilot study aimed to investigate the association between …

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Enhancing Fetal Brain MRI Segmentation in Ventriculomegaly Using Generative AI-Augmented Pathological Data

Misha Kaandorp, Damola Agbelese, Hosna Asma-ull, Kelly Payette et autres

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Automatic Lateral Ventricle and Choroid Plexus Segmentation method in infant brain MR images

Junghwa Kang, Hyun Gi Kim, Yoonho Nam

INTRODUCTION: Accurate segmentation of the lateral ventricles (LV) and choroid plexus (CP) in infant brain MRI is essential for understanding cerebrospinal fluid dynamics and early neurodevelopment. However, segmentation methods recently introduced for adult populations often underperform on infant data because of rapid …

Enhancing Pathological Fetal MRI Segmentation through Generative AI: A Novel Approach to Synthetic Pathological Data Generation

Misha Kaandorp, Hosna Asma-ull, Hyun Gi Kim, Damola Agbelese et autres

Motivation: Pathological fetal brains are difficult to segment due to limited annotated MRI data. Additionally, privacy concerns often restrict data sharing. Therefore, we need alternative augmentation techniques for improved segmentation of the pathological brain. Goal(s): To generate realistic synthetic pathological fetal brain …

Impact of CAR T cell therapy on thymus size in children and young adults with acute lymphoblastic leukemia

Iryna Vasyliv, Hyun Gi Kim, Courtney Erickson, Christina Baggott et autres

Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated efficacy in children and young adult patients with acute lymphoblastic leukemia (ALL). The purpose of our study was to investigate thymus size changes after CAR T-cell therapy, explore the associated clinical conditions, and assess …

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214P National insights into epidemiological trends and outcomes of malignant neoplasms of the small intestine: A big data analysis

J-O. Kim, Jee-Young Moon, J.H. Song, Hyun Gi Kim et autres

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