Subramaniam Krishnananthan

Desymmetrization of meso -Anhydride Enabled Enantioselective Synthesis of (−)-7-(Bromomethylene)-3-amidobicyclo[2.2.1]heptane-2-carboxamide, a Scaffold for Divergent Drug Discovery Synthesis

Jianqing Li, Subramaniam Krishnananthan, Daniel Smith, Chetan Padmakar Darne et autres

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Development of a Multigram Preparation of Optically Pure (−)-7-(Bromomethylene)-3-amidobicyclo[2.2.1]heptane-2-carboxamide BMT-395137, a Versatile Scaffold for Divergent Drug Discovery Synthesis

Jianqing Li, Daniel Smith, Lyndon A. M. Cornelius, Subramaniam Krishnananthan et autres

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Development of a Safe and Practical Synthesis of Enantiomerically Pure (S)- and (R)-N-Boc-3-(Trifluoromethyl)piperazines Enabled by Aza-Michael Addition of Optically Pure 4-Phenyl-2-Oxazolidinone to 3,3,3-Trifluoro-1-Nitropropene

Chetan Padmakar Darne, Ning Li, Daniel Smith, Shasha Zhang et autres

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Synthesis Optimization, Scale-Up, and Catalyst Screening Efforts toward the MGAT2 Clinical Candidate, BMS-963272

James Kempson, Xiaoping Hou, Jung‐Hui Sun, Michael Wong et autres

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Development of a Rapid Scale-Up Synthesis of (S)-N-(8-((2-Amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide, a Potent Adaptor-Associated Kinase 1 Inhibitor

Jianqing Li, Daniel Smith, Joseph Pawluczyk, Subramaniam Krishnananthan et autres

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Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA 1 ) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases

Peter T. W. Cheng, Robert F. Kaltenbach, Hao Zhang, Jun Shi et autres

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Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

Andrew K. Dilger, Kumar B. Pabbisetty, James R. Corte, Indawati De Lucca et autres

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CCDC 2074385: Experimental Crystal Structure Determination

Andrew K. Dilger, Kumar B. Pabbisetty, James R. Corte, Indawati De Lucca et autres

CCDC 2003382: Experimental Crystal Structure Determination

Lyndon A. M. Cornelius, Jianqing Li, Daniel T. Smith, Subramaniam Krishnananthan et autres

Synthesis of 1-(tert-Butyl) 4-Methyl (1R,2S,4R)-2-Methylcyclohexane-1,4-dicarboxylate from Hagemann’s tert-Butyl Ester for an Improved Synthesis of BMS-986251

Lyndon A. M. Cornelius, Jianqing Li, Daniel Smith, Subramaniam Krishnananthan et autres

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Multigram Synthesis of BMS-929075, an Allosteric, Palm Site Inhibitor of HCV NS5B Replicase, Involving the Synthesis of a Highly Functionalized Benzofuran through a Telescoped Process

Daniel Smith, Subramaniam Krishnananthan, Nicholas A. Meanwell, Arvind Mathur et autres

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A Practical Synthesis of the TGFβRI Inhibitor N -(4-(3-(6-(Difluoromethyl)pyridin-2-yl)-1 H -pyrrolo[3,2- b ]pyridin-2-yl)pyridin-2-yl)acetamide via One-Pot Sequential Sonogashira and Cacchi Reactions Catalyzed by Pd(OAc) 2 /BINAP

Jianqing Li, Daniel Smith, Subramaniam Krishnananthan, Arvind Mathur

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