Accès ouvert
2018
article
OpenAlex
Patrick Piero Bovio, Deborah Roidl, Stefanie Heidrich, Tanja Vogel et autres
Brain development is a complex process, which is controlled in a temporo-spatial manner by gradients of morphogens and different transcriptional programs. Additionally, epigenetic chromatin modifications, like histone methylation, have an important role for establishing and maintaining specific cell fates within this process. …
de
(code pays fourni par la source)
2018
article
OpenAlex
Patrick Piero Bovio, Deborah Roidl, Stefanie Heidrich, Tanja Vogel et autres
Brain development is a complex process, which is controlled in a temporo-spatial manner by gradients of morphogens and different transcriptional programs. Additionally, epigenetic chromatin modifications, like histone methylation, have an important role for establishing and maintaining specific cell fates within this process. …
de
(code pays fourni par la source)
Accès ouvert
2015
article
OpenAlex
Deborah Roidl, Nicole Hellbach, Patrick Piero Bovio, Alejandro Villarreal et autres
Growing evidence suggests that the lysine methyltransferase DOT1L/KMT4 has important roles in proliferation, survival, and differentiation of stem cells in development and in disease. We investigated the function of DOT1L in neural stem cells (NSCs) of the cerebral cortex. The pharmacological inhibition …
de
(code pays fourni par la source)
2015
dissertation
OpenAlex
Deborah Roidl
Accès ouvert
2014
article
OpenAlex
Nicole Hellbach, Stefan Christopher Weise, Riccardo Vezzali, Shalaka Wahane et autres
Simultaneous generation of neural cells and that of the nutrient-supplying vasculature during brain development is called neurovascular coupling. We report on a transgenic mouse with impaired transforming growth factor β (TGFβ)-signalling in forebrain-derived neural cells using a Foxg1-cre knock-in to drive the …
de
(code pays fourni par la source)
2014
article
OpenAlex
Deborah Roidl, Christine Hacker
de
(code pays fourni par la source)