Ellis Kelly

Long-range, range-resolved detection of H2 using single-photon ‘quantum’ Raman: a condition monitoring tool for long-term storage of nuclear materials

David J. M. Stothard, Matthew Warden, Roman Spesyvtsev, Ellis Kelly et autres

The stand-off, range-resolved detection of hydrogen production rates is a valuable mechanism for the long-term condition monitoring of packages containing intermediate-level nuclear materials. To exploit this effect we have developed a long-range optical sensor system which uses Raman detection of hydrogen. Our …

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Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Sophia B. Georghiou, Timothy C. Rodwell, Alexei Korobitsyn, Said Abbadi et autres

Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance.https://bit.ly/3i43wb6

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The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

Paolo Miotto, Claudio Umberto Köser, Philip William Fowler, Zamin Iqbal et autres

Background Molecular diagnostics are considered the most promising route to achievement of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC).We aimed to generate a WHO-endorsed catalogue of mutations to serve as a global standard for interpreting molecular information for drug …

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Systematic rifampicin resistance errors with Xpert® MTB/RIF Ultra: implications for regulation of genotypic assays

Shaheed Vally Omar, Doris Hillemann, Sushil Kumar Pandey, Matthias Merker et autres

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