Qiaozhu Wang

Moment of Inertia Identification of a Top Drive–Drill String System Based on Dynamic Response Analysis

Zhipeng Xu, X. Wang, Li Da Zhang, Qiaozhu Wang et autres

Accurate identification of the rotational moment of inertia of a top drive system is essential for dynamic modeling, control design, and performance optimization in drilling operations. However, the strong coupling between the drive motor, transmission components, and drill string makes direct inertia …

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ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload

Peng Liu, Lu Wang, Yixin Wang, Linyan Jin et autres

Atrial fibrillation (AF) is the most prevalent arrhythmia in clinical practice, and obesity serves as a significant risk factor for its development. The underlying mechanisms of obesity-related AF remain intricate and have yet to be fully elucidated. We have identified FPR2 as …

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Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning

Yixin Wang, Qiaozhu Wang, Peng Liu, Lingyan Jin et autres

Abstract Background Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. Nonetheless, the accurate diagnosis of this condition continues to pose a challenge when relying on conventional diagnostic techniques. Cell death is a key factor in the pathogenesis of AF. …

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Additional file 1 of Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning

Yixin Wang, Qiaozhu Wang, Peng Liu, Lingyan Jin et autres

Supplementary Material 1

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CXCL12/CXCR4 axis as a key mediator in atrial fibrillation via bioinformatics analysis and functional identification

Peng Liu, Hongke Sun, Xin Zhou, Qiaozhu Wang et autres

Abstract Atrial fibrillation (AF) is an increasingly prevalent arrhythmia with significant health and socioeconomic impact. The underlying mechanism of AF is still not well understood. In this study, we sought to identify hub genes involved in AF, and explored their functions and …

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Left Bundle Branch Pacing: Current Knowledge and Future Prospects

Peng Liu, Qiaozhu Wang, Hongke Sun, Xinghua Qin et autres

Cardiac pacing is an effective therapy for treating patients with bradycardia due to sinus node dysfunction or atrioventricular block. However, traditional right ventricular apical pacing (RVAP) causes electric and mechanical dyssynchrony, which is associated with increased risk for atrial arrhythmias and heart …

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The antagonistic effects and mechanisms of microRNA‐26a action in hypertensive vascular remodelling

Wenqian Zhang, Qiaozhu Wang, Xin Xing, Lijun Yang et autres

BACKGROUND AND PURPOSE: Hypertensive vascular remodelling is responsible for end-organ damage and is the result of increased extracellular matrix accumulation and excessive vascular smooth muscle cell (VSMC) proliferation. MicroRNA-26a (miR-26a), a non-coding small RNA, is involved in several cardiovascular diseases. We aimed …

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MicroRNA‐26a Protects the Heart Against Hypertension‐Induced Myocardial Fibrosis

Wenqian Zhang, Qiaozhu Wang, Yanjing Feng, Xuegui Chen et autres

Background Hypertensive myocardial fibrosis (MF) is characterized by excessive deposition of extracellular matrix and cardiac fibroblast proliferation, which can lead to heart failure, malignant arrhythmia, and sudden death. In recent years, with the deepening of research, microRNAs have been found to have …

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The antagonistic effects and mechanisms of microRNA-26a action in hypertensive vascular remodeling

Wenqian Zhang, Qiaozhu Wang, Xin Xing, Lijun Yang et autres

Background and Purpose: Hypertensive vascular remodeling (VR) is responsible for end-organ damage and is the result of increased extracellular matrix accumulation and excessive vascular smooth muscle cell (VSMC) proliferation. MicroRNA-26a (miR-26a), a non-coding small RNA, is involved in multiple cardiovascular diseases. We …

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MicroRNA-26a Protects the Heart Against Hypertension-Induced Ventricular Remodeling

Wenqian Zhang, Qiaozhu Wang, Yanjing Feng, Xuegui Chen et autres

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