Kenji Yanoh

Evaluation of Diagnostic Accuracy of Directly Sampled Endometrial Cytology Using ThinPrep for Endometrial Malignancies: Comparison With Existing Endometrial Liquid‐Based Cytology

Rie Ikemoto, Ken Tanikawa, Morio Ijichi, Kenji Yanoh et autres

OBJECTIVE: The aim of this study was to evaluate the accuracy of detecting malignancies by directly sampled endometrial cytology using globally adopted ThinPrep with a novel preparation technique. METHODS: Medical records and reports of pathology and cytology from June 2019 to March …

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Staining Pattern of Alcian Blue in Endometrial Cytology: Utility in Distinguishing Grade 1-Endometrial Endometrioid Carcinoma from Endometrial Glandular Stromal Breakdown

Sho Hosokawa, Yoshiaki Norimatsu, Takeshi Nishikawa, Hisae Suzuki et autres

Background and Objective: In endometrial cytology, differentiating endometrial glandular stromal breakdown (EGBD) from endometrial endometrioid carcinoma (G1-EEC) is often difficult. In this study, we provided a new focus on chondroitin sulfate (CS), a major substrate component of the endometrial stroma, and assessed …

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Discordance between the cytological diagnosis and histological diagnosis in biliary tract cytology specimens obtained using the Trefle® device

Yutaka Nakamura, Miho KAWAI, Miki Usui, Kana ASAKAWA et autres

目的：Trefle®を用いた胆管細胞診において，同一デバイスによって採取された細胞診と組織検体の診断結果が不一致となった症例について検討を行った．

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Does Vaginal Cuff Creation and Avoidance of a Uterine Manipulator Improve the Prognosis of Total Laparoscopic Radical Hysterectomy for Early Cervical Cancer? A Retrospective Multicenter Study

Eiji Kondo, Kenta K. Yoshida, Michiko Kubo‐Kaneda, Masafumi Nii et autres

Our goal was to compare the treatment outcomes of open-abdominal radical hysterectomy (O-RH) and total laparoscopic hysterectomy (TLRH) with vaginal cuff creation and without using a uterine manipulator in stage IB1-B2 (tumor size < 4 cm) cervical cancer cases. In this retrospective …

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Evaluation of Sample Adequacy: Cytologic Criteria

Yasuo Hirai, Kenji Yanoh, Yoshiaki Norimatsu, Maki Kihara

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Atypical Endometrial Cells (ATEC)

Kenji Yanoh

Morphometrical Differences among Endometrial Endometrioid Carcinoma Grade 1, Grade 3, and Serous Carcinoma in Endometrial Liquid-Based Cytology Preparations

Hirokazu Odashima, Haruhiko Yoshioka, Kouki Minami, Keita Miyakawa et autres

Introduction: In Japan, the direct smearing preparation (conventional preparation) has been widely used for cytological examination of the endometrium. Problems with the conventional preparation can be dissolved by liquid-based cytology (LBC) preparation. The Yokohama System is a method for reporting endometrial cytology, …

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Nuclear morphometry as an adjunct to cytopathologic examination of endometrial brushings on LBC samples: A prospective approach to combined evaluation in endometrial neoplasms and look alikes

Yoshiaki Norimatsu, Satoshi Irino, Yoshinobu Maeda, Kenji Yanoh et autres

OBJECTIVE: In this study, we aimed to retrospectively investigate and confirm whether atypical nuclear findings in endometrial cytology are useful when assessed by image morphometry in liquid-based cytology (LBC) and compared with microscopic evaluation. METHODS: In total, 53 cases were selected for …

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A Diagnostic Approach to Endometrial Cytology by Means of Liquid-Based Preparations

Yoshiaki Norimatsu, Kenji Yanoh, Yasuo Hirai, Tetsuji Kurokawa et autres

The adoption of endometrial cytology as a diagnostic procedure has been hampered in the past by difficulties arising in interpreting the cellular findings due to a number of factors (such as excess blood, cellular overlapping, and the complex physiology of endometrium). Recently, …

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Evaluation of cellular adequacy in endometrial liquid‐based cytology

Azusa Nimura, Ken Ishitani, Yoshiaki Norimatsu, Kaoruko Okada et autres

OBJECTIVE: This study evaluated cellular adequacy in endometrial liquid-based cytology (LBC) specimens. METHODS: In total, 1267 cases were obtained and the rate of unsatisfactory specimen and diagnostic accuracy for malignancy were assessed. If ≥10 cellular clusters composed of ≤30 endometrial cells were …

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Insulin‐like growth factor‐II mRNA‐binding protein 3 immunocytochemical expression in direct endometrial brushings: Possible diagnostic help in endometrial cytology

Yoshiaki Norimatsu, Kenji Yanoh, Yoshinobu Maeda, Satoshi Irino et autres

INTRODUCTION: This study evaluated the immunocytochemical (ICC) expression of IMP3 in direct endometrial brushings processed as liquid-based cytology (LBC) samples of endometrioid adenocarcinoma (EAC), serous carcinoma (ESC) and surface papillary syncytial change (SPSC) with endometrial glandular and stromal breakdown (EGBD) to exploit …

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Liquid‐based endometrial cytology using SurePath™ is not inferior to suction endometrial tissue biopsy for detecting endometrial malignancies: Midterm report of a multicentre study advocated by Japan Association of Obstetricians and Gynecologists

Yasuo Hirai, Kimihiko Sakamoto, Hiroyuki Fujiwara, Masaharu Kamata et autres

OBJECTIVE: We conducted a prospective, multicentre study to compare the clinical performance of liquid-based endometrial cytology (LBEC) using SurePath™ with that of suction endometrial tissue biopsy (SETB). This study is officially advocated and reported by the Japan Association of Obstetricians and Gynecologists. …

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