Does Vaginal Cuff Creation and Avoidance of a Uterine Manipulator Improve the Prognosis of Total Laparoscopic Radical Hysterectomy for Early Cervical Cancer? A Retrospective Multicenter Study
Rattachement africain : jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Our goal was to compare the treatment outcomes of open-abdominal radical hysterectomy (O-RH) and total laparoscopic hysterectomy (TLRH) with vaginal cuff creation and without using a uterine manipulator in stage IB1-B2 (tumor size < 4 cm) cervical cancer cases. In this retrospective multicenter analysis, 94 cervical cancer stage IB1-B2 patients who underwent O-RH or TLRH in six hospitals in Japan between September 2016 and July 2020 were included; 36 patients underwent TLRH. Propensity score matching was performed because the tumor diameter was large, and positive cases of lymph node metastases were included in the O-RH group due to selection bias. The primary endpoint was progression-free survival (PFS) and recurrence sites of TLRH and O-RH. PFS and OS (overall survival) were not significant in both the TLRH (n = 27) and O-RH (n = 27) groups; none required conversion to laparotomy. The maximum tumor size was <2 and ≥2 cm in 12 (44.4%) and 15 (55.6%) patients, respectively, in both groups. Reportedly, the TLRH group had lesser bleeding than the O-RH group (p < 0.001). Median follow-up was 33.5 (2−65) and 41.5 (6−75) months in the TLRH and O-RH groups, respectively. PFS and OS were not significantly different between the two groups (TLRH: 92.6%, O-RH: 92.6%; log-rank p = 0.985 and 97.2%, 100%; p = 0.317, respectively). The prognosis of early cervical cancer was not significantly different between TLRH and O-RH. Tumor spillage was prevented by creating a vaginal cuff and avoiding the use of a uterine manipulator. Therefore, TLRH might be considered efficient.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Does Vaginal Cuff Creation and Avoidance of a Uterine Manipulator Improve the Prognosis of Total Laparoscopic Radical Hysterectomy for Early Cervical Cancer? A Retrospective Multicenter Study
- Date Crossref
- 09/09/2022
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Mie University Department of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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Ise Red Cross Hospital pays non établi dans la noticeÉtablissement de santé
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Yokkaichi Municipal Hospital pays non établi dans la noticeÉtablissement de santé
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Mie Chuo Medical Center pays non établi dans la noticeÉtablissement de santé
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Matsunami General Hospital pays non établi dans la noticeÉtablissement de santé
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Suzuka Kosei Hospital pays non établi dans la noticeÉtablissement de santé
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Japanese Red Cross Ise Hospital Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Department of Obstetrics and Gynecology pays non établi dans la noticeInstitution
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Mie Central Medical Center Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Saiseikai Matsusaka General Hospital Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Suzuka General Hospital Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
Department of Obstetrics and Gynecology — Mie University, Ise Red Cross Hospital et Yokkaichi Municipal Hospital, avec 8 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.