Liquid‐based endometrial cytology using SurePath™ is not inferior to suction endometrial tissue biopsy for detecting endometrial malignancies: Midterm report of a multicentre study advocated by Japan Association of Obstetricians and Gynecologists
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Le résumé fourni par la source
OBJECTIVE: We conducted a prospective, multicentre study to compare the clinical performance of liquid-based endometrial cytology (LBEC) using SurePath™ with that of suction endometrial tissue biopsy (SETB). This study is officially advocated and reported by the Japan Association of Obstetricians and Gynecologists. By publishing our midterm data, we intend to disseminate the benefits of LBEC system, using the descriptive reporting format and algorithmic interpretational approach. METHODS: From April 2014 to December 2015, we consecutively assessed 1116 LBEC specimens and 1044 SETB specimens in our five outpatient clinics. RESULTS: The sensitivity of suction tissue biopsies was 85.2%, whereas the sensitivity of LBEC was 92.2%. The specificity of suction tissue biopsies was 98.9% and that of LBEC was 98.5%. The negative predictive value of LBEC (99.1%) was higher than that of SETB (98.1%), although the difference between these values was not significant. CONCLUSIONS: The clinical performance of LBEC for detecting endometrial malignancies was almost identical to the performance of SETB. This indicates that LBEC was not inferior to SETB for the detection of endometrial cancer. The LBEC is appropriate for various clinical situations as the first-step detecting tool. In addition, it could be used for cancer surveillance for women with signs highly suggestive of endometrial malignancies and in Lynch syndrome patients, on a larger scale.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Liquid‐based endometrial cytology using SurePath™ is not inferior to suction endometrial tissue biopsy for detecting endometrial malignancies: Midterm report of a multicentre study advocated by Japan Association of Obstetricians and Gynecologists
- Date Crossref
- 17/01/2019
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Dokkyo Medical University pays non établi dans la noticeUniversité ou école supérieure
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NTT Medical Center Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Jichi Medical University Department of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Suzuka University of Medical Science pays non établi dans la noticeUniversité ou école supérieure
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Suzuka University pays non établi dans la noticeUniversité ou école supérieure
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Suzuka Kosei Hospital pays non établi dans la noticeÉtablissement de santé
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Ehime Prefectural University of Health Science pays non établi dans la noticeUniversité ou école supérieure
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Yamanashi Prefectural Central Hospital Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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University of Fukui pays non établi dans la noticeUniversité ou école supérieure
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Shimane Prefectural Central Hospital Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Kanagawa Prefectural Hospital Organization pays non établi dans la noticeÉtablissement de santé
Dokkyo Medical University, Department of Obstetrics and Gynecology — NTT Medical Center et Department of Obstetrics and Gynecology — Jichi Medical University, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.