Hidemasa Takao

Long-term brain volume trajectories and lifestyle associations in cognitively normal adults: the Brain-Stride study

Shohei Fujita, Susumu Mori, Kengo Onda, Shouhei Hanaoka et autres

Abstract Brain aging is a major determinant of cognitive health, yet the extent of inter-individual variability in structural trajectories and its links to lifestyle factors remain incompletely understood. We conducted a single-center, prospective longitudinal cohort study within an urban academic health screening …

us, jp (code pays fourni par la source)

Subthreshold early white-matter hyperintensity increase predicts accelerated hippocampal and whole-brain atrophy in anti-amyloid-β immunotherapy

Shiori Amemiya, Hidemasa Takao, Shoya Matsumoto, Yumi Umeda‐Kameyama et autres

BackgroundAnti-amyloid-β (anti-Aβ) therapy slows cognitive decline but paradoxically accelerates whole-brain gray matter atrophy, complicating outcome prediction.ObjectiveTo identify early imaging markers that predict long-term prognoses.MethodsThis longitudinal cohort study prospectively enrolled participants with early Alzheimer's disease, initiating anti-Aβ therapy. We performed automated T1-weighted MRI …

jp (code pays fourni par la source)

Authors’ Reply to the Letter to the Editor “NBCA Sac Packing for True Visceral Artery Aneurysms: Technical Considerations for Further Advancing This Treatment Method”

Eisuke Shibata, Hidemasa Takao

jp (code pays fourni par la source)

A key gene modulating oxytocin efficacy in autism: genome-wide discovery and verification in randomized controlled trials datasets

Hitoshi Kuwabara, Masaki Kojima, Seico Benner, Takeshi Otowa et autres

jp (code pays fourni par la source)

Leveraging Task FMRI Data to Extract Resting-State Metrics in Brain Tumor and Healthy Populations

Shiori Amemiya, Jun Kanzawa, Hidemasa Takao, Osamu Abe

PURPOSE: This study examined whether task-based functional MRI (fMRI) can provide metrics of local brain activity and hemodynamics typically derived from resting-state fMRI (rsfMRI). METHODS: Two publicly open datasets from healthy individuals and brain tumor patients were retrospectively used to compare amplitude …

jp (code pays fourni par la source)

Balloon-Assisted n -Butyl Cyanoacrylate Filling of Saccular Portal and Splenic Vein Pseudoaneurysms

Eisuke Shibata, Hidemasa Takao, N. Akamatsu, Kiyoshi Hasegawa et autres

PURPOSE: -butyl-2-cyanoacrylate (nBCA) with balloon assistance. CASE REPORT: The first case was a 39-year-old female who developed a gastric ulcer after undergoing living-donor liver transplantation (LDLT) due to liver failure following surgery for congenital biliary atresia. Two saccular pseudoaneurysms were developed in …

jp (code pays fourni par la source)

Lecanemab for posterior cortical atrophy: Two contrasting cases

Kazuto Katsuse, Kazuo Kakinuma, Yoshiki Niimi, Chifumi Iseki et autres

OBJECTIVE: This study aimed to evaluate the clinical implications, limitations, and potential risks of lecanemab treatment for posterior cortical atrophy (PCA) by conducting a comparative analysis of two cases. METHOD: We retrospectively analyzed two patients with biomarker-confirmed PCA-pure who met the eligibility …

jp (code pays fourni par la source)

n-Butyl-2-Cyanoacrylate Packing of True Visceral Artery Aneurysms: A Retrospective Study of an Alternative Embolization Method

Eisuke Shibata, Hidemasa Takao, Osamu Abe

jp (code pays fourni par la source)

Spatiotemporal patterns of amyloid deposition as prognostic markers of Alzheimer’s disease

Shiori Amemiya, Hidemasa Takao, Osamu Abe

PURPOSE: The study aims to characterize the spatiotemporal distribution of amyloid deposition, differentiate between its subtypes, and explore their predictive value for patient cognitive outcomes. METHODS: Amyloid PET data from a prospective consortium study, the Alzheimer's Disease Neuroimaging Initiative, were used. A …

jp (code pays fourni par la source)

Characterizing Hemodynamic Alterations in Glioma: Insights From Resting‐State Functional MRI

Jun Kanzawa, Shiori Amemiya, Hidemasa Takao, Osamu Abe

BACKGROUND AND PURPOSE: This study aims to characterize hemodynamic alterations in gliomas by analyzing global signal metrics and amplitude of low-frequency fluctuations (ALFF). METHODS: We analyzed resting-state functional MRI data from an open dataset. A total of 29 glioma patients (17 men; …

jp (code pays fourni par la source)

N-Butyl-2-Cyanoacrylate-Assisted Balloon-Occluded Retrograde Transvenous Obliteration (NARTO) of Gastric Varices and Splenorenal Shunts

Eisuke Shibata, Hidemasa Takao, Osamu Abe

PURPOSE: This retrospective study investigated the efficacy of n-butyl-2-cyanoacrylate (nBCA)-assisted balloon-occluded retrograde transvenous obliteration (NARTO) of gastric varices and splenorenal shunts. MATERIALS AND METHODS: Between November 2021 and February 2024, 16 patients (3 females, 13 males) underwent NARTO, consisting of balloon-occluded retrograde …

jp (code pays fourni par la source)

Cross-Vendor Multiparametric Mapping of the Human Brain Using 3D-QALAS: A Multicenter & Multivendor Study

Shohei Fujita, Borjan Gagoski, Ken‐Pin Hwang, Akifumi Hagiwara et autres

Motivation: To address the unmet need for a cross-vendor, multiparametric technique to facilitate data pooling across sites. Goal(s): To evaluate a vendor-standardized multiparametric mapping scheme based on 3D-QALAS for whole-brain T1, T2, and proton density (PD) mapping. Approach: Intra-scanner repeatability and inter-vendor …