N.E.R. Goodfield

Early prediction of chemotherapy-induced cardiotoxicity

K.A. Jones, N.E.R. Goodfield

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Beta-blockers and mechanical dyssynchrony in heart failure assessed by radionuclide ventriculography

K.A. Jones, Carolyn Paterson, Stuart C. Ray, D. W. Motherwell et autres

BACKGROUND: Radionuclide ventriculography (RNVG) can be used to quantify mechanical dyssynchrony and may be a valuable adjunct in the assessment of heart failure with reduced ejection fraction (HFrEF). The study aims to investigate the effect of beta-blockers on mechanical dyssynchrony using novel …

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170 Spect myocardial coronary flow reserve - the initial glasgow experience

N.E.R. Goodfield, Richard A. McFarlane, Craig A. Paterson, Jamie R. Robinson et autres

Introduction Identification of myocardial ischaemia & the need for mechanical intervention has increasingly become dependent on measurements of coronary artery flow in terms of FFR, CMR & IMR at invasive coronary angiography & coronary flow reserve (CFR) at CTCA, in addition to …

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Optimising approximate entropy for assessing cardiac dyssynchrony with radionuclide ventriculography

K.A. Jones, Carolyn Paterson, D. Hamilton, A.D. Small et autres

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Mechanical dyssynchrony and super-response to CRT

K.A. Jones, N.E.R. Goodfield

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Radionuclide ventriculography phase analysis for risk stratification of patients undergoing cardiotoxic cancer therapy

K.A. Jones, A.D. Small, Surajit Ray, D. Hamilton et autres

BACKGROUND: Accurate diagnostic tools to identify patients at risk of cancer therapy-related cardiac dysfunction (CTRCD) are critical. For patients undergoing cardiotoxic cancer therapy, ejection fraction assessment using radionuclide ventriculography (RNVG) is commonly used for serial assessment of left ventricular (LV) function. METHODS: …

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Poster session: Aortic stenosis

Ivan M. Jovanović, M. Tesic, Ivana Paunović, Milan R. Dobric et autres

Background: Patients with left main coronary artery (LMCA) stenosis are considered to be vulnerable population that requires reliable assessment of functional significance of lesions observed on coronary angiography.The aim of this study was to determine the prognostic value of noninvasively measured coronary …

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I-123 MIBG cardiac uptake measurements: limitations of collimator choice and scatter correction in the clinical context

Alison M. Fletcher, Duncan W. Motherwell, A.D. Small, Graham M. McCurrach et autres

OBJECTIVE: Low uptake of metaiodobenzylguanidine (MIBG) in patients with heart failure generally indicates poor prognosis. Our objective was to determine the best method for calculating I-123 MIBG uptake. MIBG uptake as a percentage of the injected dose is presented as an alternative …

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Three-dimensional echocardiography for optimization of cardiac resynchronization therapy: reply

Tony Stanton, Nathaniel Mark Hawkins, Karen J. Hogg, N.E.R. Goodfield et autres

We thank Ballo et al. for their comments regarding the possible use of three-dimensional (3D) echocardiography for the optimization of cardiac resynchronization therapy (CRT). Three-dimensional echocardiography has been used to assess ventricular dyssynchrony1 as well as ventricular volumes and function.2 We agree …

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Optimising Direct Access Echo Referral in Suspected Heart Failure

Mitchell M Lindsay, N.E.R. Goodfield, Karen J. Hogg, F G Dunn

The objective was to prospectively validate a method of increasing the sensitivity, specificity and negative predictive value of a normal ECG in the exclusion of left ventricular systolic dysfunction by the addition of clinical history. We performed a prospective three year study …

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Effects of Acute Angiotensin II Type 1 Receptor Antagonism and Angiotensin Converting Enzyme Inhibition on Plasma Fibrinolytic Parameters in Patients With Heart Failure

N.E.R. Goodfield, David Ernest Newby, Christopher A. Ludlam, Andrew D. Flapan

BACKGROUND: Angiotensin converting enzyme (ACE) inhibition after myocardial infarction is associated with an improvement in plasma fibrinolytic parameters. The aim of the present study was to determine whether acute ACE inhibition and angiotensin II type 1 (AT1) receptor antagonism have similar effects …

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Regulation of peripheral vascular tone in patients with heart failure: contribution of angiotensin II

David Ernest Newby, N.E.R. Goodfield, Andrew D. Flapan, Nico Boon et autres

OBJECTIVE: To determine directly the contribution of angiotensin II to basal and sympathetically stimulated peripheral arteriolar tone in patients with heart failure. DESIGN: Parallel group comparison. SUBJECTS: Nine patients with New York Heart Association grade II-IV chronic heart failure, and age and …

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