Luyu Xie

Updated Waist Circumference Percentiles and Central Obesity Prevalence Among U.S. Children and Adolescents, NHANES 2011–2023

Rabiya K Mian, Luyu Xie, Yasmin Hamad, Sitapriya S. Neti et autres

Background: Pediatric obesity affects 20% of children and adolescents globally. Waist circumference (WC) identifies central adiposity and cardiometabolic risk, yet pediatric WC percentiles are outdated. This study provides updated age- and sex-specific WC percentiles reflecting current trends to improve clinical risk assessment. …

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Discordance between International Classification of Diseases, 10th Revision asthma severity codes and treatment-based measures of disease severity

Yixin Tang, Jeffrey Chambliss, Zhenglin Yuan, Wenqi Shi et autres

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Discordance between adiposity and FIB-4 risk classification in US adults

Luyu Xie, Diego Añazco, AZUCENA HERRERA CHANCAY, Sarah Messiah et autres

Purpose: The fibrosis-4 index (FIB-4) is a widely used noninvasive tool for fibrosis risk stratification, however, the relationship between adiposity and FIB-4-based risk classification remains unclear. We evaluated the associations between multiple measurements of adiposity and FIB-4 risk classification in a nationally …

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Molecular phenotypes and spatial archetypes: A new framework for cancer-associated fibroblasts

Y Liu, Xiongfeng Chen, Yibo Dai, Yiyue Jia et autres

Cancer-associated fibroblasts (CAFs) form a dynamic ecosystem that critically influences tumor progression and therapeutic response. Although recent advances in single-cell and spatial omics have uncovered profound stromal diversity, interpreting the mechanistic relevance of this complexity remains a challenge. Here, we propose a …

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Out-of-Pocket Expenses Associated with Hand Trauma: A 12-Month Analysis After Injury

Denzil P. Mathew, Victoria F. Peters, Hailey Holck, Daniel Villarreal et autres

INTRODUCTION: Hand injuries impose financial burdens that can delay care and impact outcomes. However, there is a lack of information about the impact of different patient, injury, and health system factors that drive patient out-of-pocket (OOP) expenses. METHODS: We performed a retrospective …

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National Prevalence and Predictors of Asthma Remission in the United States

Zhenglin Yuan, Fariha Imitaz, Yixin Tang, Timothy G. Chow et autres

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Association between asthma and dementia across age groups

Yutong Chen, Joo-Han Kim, Timothy Chow, Arthur S. Hong et autres

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Obesity and Severe Obesity in Youth Before and During COVID-19

Sarah Messiah, Yujia Guo, Luyu Xie, D. Ernest et autres

BACKGROUND AND OBJECTIVES: Childhood obesity has remained persistently high in the United States. This study aimed to (1) assess changes in obesity prevalence and (2) examine the associations of ultra-processed food (UPF) intake and physical activity (PA) patterns with obesity, by obesity …

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High Blood Pressure

Steven E. Lipshultz, Sarah Messiah, Lauren A. Sarno, Luyu Xie et autres

Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches

Xiongfeng Chen, Zhuan Zhou, Luyu Xie, Kailiang Qiao et autres

Recent studies identify a unique subtype of cancer-associated fibroblasts (CAFs) termed antigen-presenting CAFs (apCAFs), which remain poorly understood. To gain a comprehensive understanding of the origin and function of apCAFs, we construct a fibroblast molecular atlas across 15 types of tissues and …

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Cost-related barriers to medication use among diverse participants with obesity-associated asthma

Luyu Xie, Joohan Kim, Jaime P. Almandoz, Folashade Afolabi et autres

BACKGROUND: Individuals with obesity-associated asthma (OAA) have worse health outcomes than those with asthma and healthy weight (no OAA). The impact of cost barriers on medication use and how it varies by racial and ethnic groups is unclear. OBJECTIVE: To assess the …

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Total Payments and Out-of-Pocket Expenses for Surgical Hand Trauma Episodes

Jessica I. Billig, Yixin Tang, Michael Wu, Luyu Xie et autres

PURPOSE: Insight about episode spending after elective procedures has driven interest in bundling reimbursement for surgical procedures. However, little is known about episode spending for health systems (payments) and patients (out-of-pocket [OOP] expenses) after unplanned, nonelective procedures such as hand trauma. METHODS: …

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