Molecular Genotyping of Circulating Enterovirus in the Lazio Region from 2012 to 2023
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Enteroviruses (EVs) are ubiquitous viruses that circulate worldwide, causing sporadic or epidemic infections, typically during the summer and fall. They cause a broad spectrum of illnesses, ranging from an unspecified febrile clinical presentation to a severe illness. EVs are recognized to be the most frequent etiological agents of aseptic meningitis in children. However, as the infection is usually mild and self-limiting, it remains underestimated, and the epidemiology of EVs is poorly understood. To date, no vaccine or effective therapy for all types of enteroviruses is available, and EVs constitute a public health concern. Here, we investigated the molecular epidemiology of EV strains circulating in the Lazio region over a 10-year time span (2012-2023) by using a sequence-typing approach and phylogenetic analysis. The epidemiological trend of EV infection has undergone changes during the SARS-CoV-2 pandemic (2020-2021), which resulted in a modification in terms of the number of diagnosed cases and seasonality. From 2022, the circulation of EVs showed a behavior typical of the pre-pandemic period, although changes in predominantly circulating strains have been noted. Both epidemic and sporadic circulation events have been characterized in the Lazio region. Further analyses are needed to better characterize any strain with higher potential pathogenic power and to identify possible recombinant strains.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Molecular Genotyping of Circulating Enterovirus in the Lazio Region from 2012 to 2023
- Date Crossref
- 24/06/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani pays non établi dans la noticeÉtablissement de santé
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Istituti di Ricovero e Cura a Carattere Scientifico pays non établi dans la noticeÉtablissement de santé
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Regione Lazio pays non établi dans la noticeOrganisme public
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Policlinico Casilino Neonatology and Neonatal Intensive Care Unit pays non établi dans la noticeÉtablissement de santé
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Policlinico Umberto I Department of Public Health and Infectious Diseases pays non établi dans la noticeÉtablissement de santé
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Laboratory of Virology pays non établi dans la noticeStructure de recherche
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National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS Regional Service for Surveillance and Control of Infectious Diseases (SERESMI)-Lazio Region pays non établi dans la noticeStructure de recherche
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National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS Regional Service for Surveillance and Control of Infectious Diseases (SERESMI)-Lazio Region pays non établi dans la noticeStructure de recherche
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Istituti di Ricovero e Cura a Carattere Scientifico et Regione Lazio, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.