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2023
article
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
Bang Zheng, Giulia Vivaldi, Luke Daines, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth Saunders, Victoria Harris, Linzy Houchen‐Wolloff, Neil Greening, Paul Pfeffer, John R. Hurst, Jeremy Brown, Manu Shankar‐Hari, Carlos Echevarria, Anthony De Soyza, Ewen M. Harrison, Annemarie B Docherty, Nazir Lone, Jennifer K Quint, James D. Chalmers, Ling‐Pei Ho, Alex Horsley, Michael Marks, Krishna Poinasamy, Betty Raman, Liam G. Heaney, Louise V. Wain, Rachael A Evans, Christopher E. Brightling, Adrian R. Martineau, Aziz Sheikh, Kathryn M. Abel, Huzaifa Adamali, Davies Adeloye, O Adeyemi, R Adrego, L A Aguilar Jimenez, Shazaad Ahmad, Nafees Haider, Rizwan Ahmed, N Ahwireng, Mark Ainsworth, B Al-Sheklly, A Alamoudi, Mohammad Ali, M Aljaroof, A.M. All, Louise Allan, R Allen, L. Allerton, Lynne Allsop, P. Almeida, Doris Altmann, Maria Alvarez Corral, S Amoils, Debra Anderson, Chrystalina A. Antoniades, A. Arias, Chérie Armour, Lará Armstrong, Natalie Armstrong, David Arnold, H Arnold, Abdul Ashish, Andrew Ashworth, Mark Ashworth, S Aslani, H Assefa-Kebede, Catherine Atkin, Philip A. Atkin, Raminder Aul, Htin Aung, Luke Austin, Cristina Avram, A Ayoub, Marta Babores, Rob Baggott, J. Bagshaw, David Baguley, L. Charles Bailey, J. Kenneth Baillie, S. Bain, M Bakali, M Bakau, Eileen Baldry, David Baldwin, Molly M Baldwin, Clive Ballard, Amitava Banerjee, B. Bang, Ruth E Barker, L Barman, Shaney Barratt, Fiona Barrett, D Basire, N Basu, M. Bates, Andrew Bates, Rachel L. Batterham, Helen Baxendale, Hannah Bayes, Michael Beadsworth, P Beckett, M. Beggs, M Begum, Paul Beirne, D Bell, Robert M. Bell, Katherine Bennett, Eva Beranová, Areti Bermperi, A Berridge, Colin Berry, Sarah Betts, Emily Bevan, Kam Bhui, M Bingham, K Birchall, Lisa Bishop, Karen Bisnauthsing, J Blaikely, Angela Bloss, A Bolger, Charlotte E. Bolton, James Bonnington, A Botkai, C Bourne, Michelle Bourne, Kate Bramham, L Brear, Gerome Breen, J Breeze, Andrew Briggs, E Bright, Simon Brill, Khara Croswaite Brindle, L. Broad, A Broadley, C Brookes, Matthew R. Broome, A. Brown, Martin M. Brown, Victoria Tzortziou Brown, Traolach Brugha, Nigel J. Brunskill, Maya H Buch, Philip Buckley, Anda Bularga, Edward T. Bullmore, L. Burden, Teresa Burdett, D Burn, G Burns, Angus C. Burns, John Busby, R. Butcher, Adeel A. Butt, Suzanne Byrne, Paula Cairns, P C Calder, E Calvelo, H Carborn, Brittany Card, Christine Carr, L. Carr, Gail Carson, P. Carter, Anna Casey, Mark Philip Cassar, Jorunn Pauline Cavanagh, Manish Chablani, Trudie Chalder, R C Chambers, Francis K.L. Chan, K.M. Channon, K Chapman, A Charalambou, Nazia Chaudhuri, Anna M. Checkley, J. Chen, Yu Cheng, L Chetham, C Childs, Edwin R. Chilvers, Hector Chinoy, Amedeo Chiribiri, K Chong-James, Gourab Choudhury, Noura J. Choudhury, Phil Chowienczyk, C D C Christie, M Chrystal, Diane Clark, Collin M. Clark, Jennifer Clarke, Sara Clohisey, G Coakley, Z Coburn, S Coetzee, Joby Cole, Christopher M. Coleman, F Conneh, David Connell, Bronwen Connolly, L Connor, A Cook, Brendan Cooper, D. James Cooper, Sheldon C. Cooper, Debra Copeland, Tracey Cosier, M Coulding, C Coupland, Eline G. M. Cox, Tom Craig, Philippe Crisp, D Cristiano, Michael G. Crooks, Adam Cross, I Cruz, Paul Cullinan, Daniel J. Cuthbertson, M Dalton, Patricia Daly, A Daniels, Paul Dark, J Dasgin, Abel P. David, Elin Haf Davies, Ffyon Davies, Gwyneth A. Davies, Katherine Davies, Matthew Davies, Jennifer Dawson, E Daynes, B Deakin, Andrew Deans, C Deas, J Deery, Sylviane Defres, Amanda Dell, K Dempsey, Emma Denneny, John Dennis, Amy Dewar, R Dharmagunawardena, N Diar-Bakerly, Chris Dickens, A Dipper, Sarah Diver, S N Diwanji, Michael J. Dixon, Ratko Djukanović, Hannah Dobson, Susan L. Dobson, A Donaldson, Tim Dong, Natalie Dormand, Andrew Dougherty, Rowan Dowling, S Drain, K Draxlbauer, K. Drury, H.J.C. drury, P Dulawan, A Dunleavy, S Dunn, C. Dupont, J Earley, Nicholas Easom, Sarah Edwards, Charlotte L. Edwardson, H El-Taweel, Angela Elliott, Katharine Elliott, Y Ellis, A Elmer, D Evans, Helen Evans, Jonathan Evans, Rhodri Evans, Teriann Evans, C Evenden, Lynsey Evison, Laura Fabbri, Sara Fairbairn, Andrea D. Fairman, K Fallon, David Faluyi, C Favager, T Fayzan, J. Featherstone, Tim Felton, J Finch, Simon J. Finney, J Finnigan, Lucy Finnigan, Helen L. Fisher, Simon Fletcher, R Flockton, M. G. Flynn, H Foot, David Foote, James D. Ford, Daniel Forton, E Fraile, C Francis, Rebecca Francis, Sarah Francis, Adam Frankel, Emily Fraser, Robert C. Free, Nigel French, Xiaotong Fu, Jonathan Fuld, James Furniss, L. Garner, Nandan Gautam, J R Geddes, P M George, Michael Gibbons, Michael Gill, L Gilmour, Fergus Gleeson, J Glossop, S. W. Glover, Nigel Goodman, C Goodwin, Bibek Gooptu, Howard S. Gordon, T Gorsuch, M Greatorex, Paul L. Greenhaff, William Greenhalf, A Greenhalgh, John P. Greenwood, H Gregory, R. Gregory, D Grieve, Denise Griffin, Lori Griffiths, A-M Guerdette, Mahitha Gummadi, Ayush Gupta, Sambasivarao Gurram, Elspeth Guthrie, Z Guy, H Henson, Kate Hadley, A Haggar, Kirsten Hainey, Brigid Hairsine, Pranabashis Haldar, Isabella Hall, L Hall, Mark Halling‐Brown, R Hamil, A Hancock, Kerry Hancock, Neil A. Hanley, Sulaimaan Haq, Hayley Hardwick, Elaine Hardy, T Hardy, Beverley Hargadon, Kevin J. Harrington, Emma Harris, Phillippa Harrison, Nicholas Hart, A Harvey, M Harvey, M Harvie, Lynn Haslam‐Larmer, May Havinden-Williams, Jason E. Hawkes, N Hawkings, J Haworth, Adrian Hayday, M Haynes, Jon Hazeldine, T Hazelton, Cheryl Heeley, Jonathan L. Heeney, Melissa Heightman, Simon Heller, Morag Henderson, L Hesselden, Melissa Hewitt, V Highett, Toby Hillman, T Hiwot, A Hoare, M Hoare, J Hockridge, P Hogarth, A Holbourn, Sara Holden, Luke Holdsworth, D Holgate, M Holland, L Holloway, K. Holmes, Manisha Holmes, B Holroyd-Hind, L Holt, Anil Hormis, Akram A. Hosseini, Matthew Hotopf, Kirsten Howard, Luke Howard, Alice Howell, E Hufton, Alun D. Hughes, Joel W. Hughes, R Hughes, A Humphries, Nathan T. M. Huneke, E Hurditch, Masud Husain, Tracy Hussell, J Hutchinson, Wadah Ibrahim, F Ilyas, J Ingham, L Ingram, D Ionita, K Isaacs, Khalida Ismail, Thomas Jackson, Joseph Jacob, W Y James, Woo Young Jang, C Jarman, Ian Jarrold, Hannah Jarvis, R Jastrub, B Jayaraman, Gísli Jenkins, Peter Jezzard, K Jiwa, Candace Johnson, Steven Johnson, D Johnston, Caroline J. Jolley, D Jones, Graeme Jones, H. Jones, Ian A. Jones, L Jones, Mark G. Jones, S Jones, S Jose, T Kabir, Georgios Kaltsakas, Vicky Kamwa, N. Kanellakis, Zunaira Kausar, Natalie Keenan, Sadie Kelly, Graham J. Kemp, S Kerr, Helen Kerslake, A L Key, Fasihul Khan, Kamlesh Khunti, Susan Kilroy, B. King, C King, L. Kingham, Jodie Kirk, Pádraig T. Kitterick, Paul Klenerman, Lucy Knibbs, Susan Knight, A. Knighton, Onn Min Kon, Samantha S.C. Kon, S. Koprowska, Ania Korszun, Ivan Koychev, C Kurasz, P Kurupati, Charles Laing, H. Lamlum, G Landers, Claudia Langenberg, Daniel Lasserson, Lara Lavelle-Langham, Alison M. Lawrie, Claire Lawson, A Layton, A Lea, D. Lee, J.-H. Lee, E. Lee, K. Leitch, R Lenagh, Daniel J. Lewis, J. R. Lewis, Keir Lewis, Virginia Lewis, N Lewis-Burke, X. Li, Teresa Light, Liz Lightstone, W. Lilaonitkul, L. Lim, S Linford, Anne Lingford‐Hughes, Marc Lipman, Kamal Liyanage, Adam Lloyd, Sarah Logan, David A. Lomas, Ronda Loosley, Janet M. Lord, Harpreet Lota, Wayne Lovegrove, Alice Lucey, Elena Lukaschuk, A Lye, C. Lynch, Steven MacDonald, Guy MacGowan, Irene Macharia, J Mackie, L Macliver, S Madathil, G Madzamba, N Magee, M M Magtoto, N Mairs, Nauman Majeed, Eugene O. Major, Flora Malein, Michael H. Malim, Georgia Mallison, William D‐C Man, Sema Mandal, Kenneth Mangion, Charlotte Manisty, R Manley, Keith L. March, Stefan J. Marciniak, Pietro Marino, M Mariveles, E Marouzet, S. Marsh, Ben G. Marshall, Michael S. Marshall, James Martín, Leonardo Martín Vásquez Martínez, Nick Maskell, Darwin Matila, Wadzanai Matimba-Mupaya, Lauren Matthews, A Mbuyisa, Stephen P. McAdoo, R. Hamish McAllister‐Williams, Angela McArdle, P McArdle, D McAulay, Gerry P McCann, Jacqueline McCormick, W McCormick, P McCourt, Lorcan McGarvey, Christopher McGee, Kirsty McGee, J McGinness, K McGlynn, A McGovern, Heather McGuinness, Iain B. McInnes, J McIntosh, E McIvor, K McIvor, L McLeavey, Anne McMahon, Michael McMahon, Liam McMorrow, T Mcnally, Melitta A. McNarry, J McNeill, Alison McQueen, H McShane, C Mears, C Megson, S Megson, Puja Mehta, James Meiring, L Melling, Mark Mencias, Dan Menzies, Marta Merida Morillas, A. Michael, Chris Miller, Lea Milligan, C Mills, Gary Mills, Nicholas L. Mills, L Milner, S Misra, James Mitchell, A. Mohamed, N Mohamed, Sarhan Mohammed, Philip L. Molyneaux, W Monteiro, S Moriera, Anna Morley, Leigh Morrison, Richard Morriss, A Morrow, Alison Moss, Paul Moss, K Motohashi, N Msimanga, Elizabeta B. Mukaetova‐Ladinska, U Munawar, Jennifer Murira, Uttam Nanda, H Nassa, M Nasseri, A Neal, R. Needham, P Neill, Stefan Neubauer, David E. Newby, Helen Newell, Tom Newman, Julia Newman, A. Newton-Cox, Timothy R. Nicholson, D Nicoll, A. Nikolaidis, Claire M. Nolan, Maria Noonan, Chris Norman, Petr Novotný, J Nunag, Lorenza Nwafor, U Nwanguma, J Nyaboko, Conor O’Brien, Kate O’Donnell, David O’Regan, L O'Brien, N Odell, Graham S. Ogg, O Olaosebikan, C Oliver, Z Omar, Peter Openshaw, L. 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Semple, T Sewell, Abhijit Shah, Kanan Shah, Pallav L. Shah, Manish Sharma, Claire C. Sharpe, Michael Sharpe, S Shashaa, Albert C. Shaw, Kaitlin Shaw, Victoria Shaw, Sarah Shelton, L Shenton, K Shevket, A Shikotra, Jay M. Short, S Siddique, Salman Siddiqui, J Sidebottom, Louise Sigfrid, G Simons, Jennifer Simpson, Nicholas Simpson, Claire Singh, Sally Singh, D Sissons, J Skeemer, Katie Slack, Anne Smith, D Smith, Susan M. Smith, John A. Smith, Lauren C. Smith, M Soares, T S Solano, Reanne Solly, A R Solstice, T Soulsby, David Southern, D. Sowter, Mark Spears, Lisa Spencer, F Speranza, Louise Stadon, Stefan Stanel, N Steele, Michael Steiner, David J. Stensel, G Stephens, L Stephenson, M Stern, Iain Stewart, R Stimpson, Skye Stockdale, James Stockley, William Thornley Stoker, Richard Stone, W Storrar, A. Storrie, Kim Storton, Jeffrey S. A. 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Wainwright, L O Wajero, S Walder, S Walker, Emma Wall, T Wallis, Sharon Walmsley, Jessica A. Walsh, S Walsh, L Warburton, Tom Ward, K Warwick, Helen Wassall, Sharon Waterson, Eleanor Watson, Lea C. Watson, Judith Watson, Carly Welch, H Welch, B Welsh, Simon Wessely, S West, H Weston, Helen Wheeler, Simon R. White, Victor Whitehead, Julie Whitney, Spence Whittaker, B. Whittam, V Whitworth, Andrew Wight, Jim M. Wild, M Wilkins, Dean Wilkinson, Bryan Williams, Nefyn Williams, Justin Williams, S A Williams-Howard, Michelle Willicombe, Guillermo B. Willis, J Willoughby, A Wilson, David M. Wilson, Iseult Wilson, Nicola Window, Miles D. Witham, R Wolf-Roberts, C Wood, Felix Woodhead, Jeffrey A. Woods, Dan Wootton, Joanne Wormleighton, J Worsley, David C. Wraith, C Wrey Brown, Clinton B. Wright, L Wright, S. Wright, J Wyles, Inez Wynter, Mengxin Xu, N Yasmin, S Yasmin, Thomas Yates, Kay Por Yip, Bob Young, Scott Young, Alison L. Young, Ahmed Yousuf, A. Zawia, Lisa Zeidan, Boya Zhao, O Zongo
30Citations signalées — pas une note de qualité
27Institutions déclarées
1Pays d’affiliation déclarés
Résumé fourni par la source
Background: The risk factors for recovery from COVID-19 dyspnoea are poorly understood. We investigated determinants of recovery from dyspnoea in adults with COVID-19 and compared these to determinants of recovery from non-COVID-19 dyspnoea. Methods: We used data from two prospective cohort studies: PHOSP-COVID (patients hospitalised between March 2020 and April 2021 with COVID-19) and COVIDENCE UK (community cohort studied over the same time period). PHOSP-COVID data were collected during hospitalisation and at 5-month and 1-year follow-up visits. COVIDENCE UK data were obtained through baseline and monthly online questionnaires. Dyspnoea was measured in both cohorts with the Medical Research Council Dyspnoea Scale. We used multivariable logistic regression to identify determinants associated with a reduction in dyspnoea between 5-month and 1-year follow-up. Findings: We included 990 PHOSP-COVID and 3309 COVIDENCE UK participants. We observed higher odds of improvement between 5-month and 1-year follow-up among PHOSP-COVID participants who were younger (odds ratio 1.02 per year, 95% CI 1.01-1.03), male (1.54, 1.16-2.04), neither obese nor severely obese (1.82, 1.06-3.13 and 4.19, 2.14-8.19, respectively), had no pre-existing anxiety or depression (1.56, 1.09-2.22) or cardiovascular disease (1.33, 1.00-1.79), and shorter hospital admission (1.01 per day, 1.00-1.02). Similar associations were found in those recovering from non-COVID-19 dyspnoea, excluding age (and length of hospital admission). Interpretation: Factors associated with dyspnoea recovery at 1-year post-discharge among patients hospitalised with COVID-19 were similar to those among community controls without COVID-19. Funding: PHOSP-COVID is supported by a grant from the MRC-UK Research and Innovation and the Department of Health and Social Care through the National Institute for Health Research (NIHR) rapid response panel to tackle COVID-19. The views expressed in the publication are those of the author(s) and not necessarily those of the National Health Service (NHS), the NIHR or the Department of Health and Social Care.COVIDENCE UK is supported by the UK Research and Innovation, the National Institute for Health Research, and Barts Charity. The views expressed are those of the authors and not necessarily those of the funders.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
- Date Crossref
- 01/06/2023
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Sujets associés
Long-Term Effects of COVID-19COVID-19 Clinical Research StudiesDermatological and COVID-19 studies