Accès ouvert déclaré
2022
article
Incisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART)
Jared Torkington, Rhiannon Harries, Susan O’Çonnell, Laura Knight, Saiful Islam, Nadim Bashir, Alan Watkins, Greg Fegan, Julie Cornish, B I Rees, Hannah Cole, Hannah Jarvis, Stefanie A Jones, Ian Russell, David C. Bosanquet, Anne Cleves, Bernadette Sewell, Angela Farr, N Zbrzyzna, N Fiera, Rwth Ellis‐Owen, N. Zoe Hilton, Chris M. Parry, Andrew W. Bradbury, Peter Wall, James Hill, D. C. Winter, Kim Cocks, Dean Harris, J. Hilton, Stelios Vakis, D. Hanratty, R. Rajagopal, F. Akbar, A Ben-Sassi, Nader Francis, Louise Jones, M. E. R. Williamson, Ian Lindsey, Robert West, Christopher J. Smart, Paul Ziprin, Tulika Mehta Agarwal, G Faulkner, Thomas Pinkney, Dale Vimalachandran, D Lawes, Omar Faiz, Pasha J. Nisar, Neil Smart, Tim Wilson, Angela Myers, Jonathan N. Lund, Sebastian Smolarek, Austin G. Acheson, James Horwood, James Ansell, Simon Phillips, Matthew L. Davies, Linda Davies, Shawn J. Bird, N Palmer, Michael L. Williams, Giorgios Galanopoulos, Pryangka Rao, Rebecca E. Barnett, Sophia Tate, J Wheat, Neil Patel, Shaghayegh Rahmani, E Toynton, Laurie Smith, Nicola Reeves, E Kealaher, G Williams, C Sekaran, Mary Evans, J Beynon, Richard Egan, Ebtisam R Qasem, U Khot, Sarim Ather, P Mummigati, Graham W. Taylor, J Williamson, J Lim, Anathea C. Powell, H Nageswaran, A. Williams, J Padmanabhan, Katherine W. Phillips, Tamsin Ford, John Edwards, Nils R. Varney, Lucy Hicks, C. V. Greenway, Karen Chesters, Helen M.F. Jones, P A Blake, Gina Brown, L Roche, Mark Feeney, P Shah, Carolyn M. Rutter, Colman McGrath, Nathan Curtis, Lucy Pippard, James Perry, J Allison, Jonathan Ockrim, Richard Dalton, Andrew Allison, Jennifer Rendell, Linda Howard, K Beesley, Godwin Dennison, Julie Burton, Grace Bowen, S Duberley, Lance Richards, Joanna L. Giles, Joyce Katebe, Susanne Oksbjerg Dalton, James B. Wood, E. Courtney, Roel Hompes, A Poole, Stephen A. Ward, Lawrence H. Wilkinson, Lisa Hardstaff, M Bogden, Mohammed Al-Rashedy, Catherine Fensom, Neil Lunt, Marilyn McCurrie, Rebekah Peacock, K. Malik, Hannah Burns, B. Townley, P Hill, M M Sadat, Umar Daraz Khan, C Wignall, D Murati, Melanie Dhanaratne, Sheena Quaid, Sambasivarao Gurram, Dave Smith, Pastor C. Harris, J. S. Pollard, Gene DiBenedetto, James Chadwick, R. Hull, Simon P. Bach, Dion Morton, K Hollier, V. Hardy, Maryam Ghods, Dana Tyrrell, Shazad Q. Ashraf, James Glasbey, Muhammad Ashraf, Sean Garner, Andrew Whitehouse, D. Yeung, S Noor Mohamed, Richard Wilkin, Nigel Suggett, C Lee, Atul Bagul, C. McNeill, N Eardley, Rajendra Mahapatra, C. Gabriel, Pooja Datt, S. Mahmud, I. R. Daniels, Frank McDermott, M Nodolsk, L Park, Humphrey Scott, J. P. Trickett, Philip Bearn, Prateesh Trivedi, Victoria Frost, Catherine Gray, Michael Croft, D Beral, J. Osborne, R Pugh, G. Herdman, Rosalyn George, A-M Howell, S Al-Shahaby, B Narendrakumar, Youstina Mohsen, Samreen Ijaz, Mariam Nasseri, P Herrod, Tr Brear, J-J Reilly, A Sohal, Calford Otieno, WK Lai, Mark Coleman, Esther Platt, A Patrick, Catherine L. Pitman, S. Balasubramanya, Edward Dickson, Rhian Warman, Charles R. Newton, S Tani, John Simpson, Ambar Banerjee, Arifa Siddika, D. S. Campion, David J. Humes, Navkiran Randhawa, J. Saunders, Balamurali Bharathan, Ori Hay
29Citations signalées, ce qui n’est pas une note de qualité
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Le résumé fourni par la source
BACKGROUND: Incisional hernias cause morbidity and may require further surgery. HART (Hughes Abdominal Repair Trial) assessed the effect of an alternative suture method on the incidence of incisional hernia following colorectal cancer surgery. METHODS: A pragmatic multicentre single-blind RCT allocated patients undergoing midline incision for colorectal cancer to either Hughes closure (double far-near-near-far sutures of 1 nylon suture at 2-cm intervals along the fascia combined with conventional mass closure) or the surgeon's standard closure. The primary outcome was the incidence of incisional hernia at 1 year assessed by clinical examination. An intention-to-treat analysis was performed. RESULTS: Between August 2014 and February 2018, 802 patients were randomized to either Hughes closure (401) or the standard mass closure group (401). At 1 year after surgery, 672 patients (83.7 per cent) were included in the primary outcome analysis; 50 of 339 patients (14.8 per cent) in the Hughes group and 57 of 333 (17.1 per cent) in the standard closure group had incisional hernia (OR 0.84, 95 per cent c.i. 0.55 to 1.27; P = 0.402). At 2 years, 78 patients (28.7 per cent) in the Hughes repair group and 84 (31.8 per cent) in the standard closure group had incisional hernia (OR 0.86, 0.59 to 1.25; P = 0.429). Adverse events were similar in the two groups, apart from the rate of surgical-site infection, which was higher in the Hughes group (13.2 versus 7.7 per cent; OR 1.82, 1.14 to 2.91; P = 0.011). CONCLUSION: The incidence of incisional hernia after colorectal cancer surgery is high. There was no statistical difference in incidence between Hughes closure and mass closure at 1 or 2 years. REGISTRATION NUMBER: ISRCTN25616490 (http://www.controlled-trials.com).
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Incisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART)
- Date Crossref
- 05/08/2022
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
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Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Les sujets associés
Hernia repair and managementMinimally Invasive Surgical TechniquesIntestinal and Peritoneal Adhesions