Ebtisam R Qasem

Prognostic and Therapeutic Implications of ADAM17 and TRIM24in Epithelial Ovarian Carcinomas

Asmaa Hussein mohamed, Ebtisam R Qasem, Mona Salah, Eslam G Abozaid et autres

Ovarian cancer is a lethal gynecological malignancy as it represents the 5th leading cause of death among women. So, it is an important issue for novel biomarkers identification for its early diagnosis and improving the efficacy of ovarian cancer treatment. A disintegrin …

Predictive value of androgen receptor expression for pathological complete response in HER2-positive breast cancer treated with neoadjuvant TCHP: A prospective study

Moamna Mohammad Fahmy, Eman Saad Abdel Raof, Ibrahim Ali Heggy, Adel Mohamed Ismail et autres

Clinico-Dosimetric Correlation Between Lacrimal Gland Dose and Dry Eyes in Three Dimensional Radiotherapy of Brain Tumors

Ebtisam R Qasem, Abbas Sarhan, Salma Khaled Abd El-Maksoud, Doaa Mandour

Background: Brain tumors often require radiotherapy as a key component of treatment. While three-dimensional conformal radiotherapy (3D-CRT) provides better dose distribution compared to conventional techniques, organs at risk (OARs) such as the lacrimal glands may still receive significant radiation exposure. Evaluating the …

Égypte (code pays fourni par la source)

Clinicopathological implications of FGL1, PD-L1 and CMTM6 expressions in hepatocellular carcinoma and their correlation to patients' survival

Hanan M Lotfy, Noha F. Elaidy, Tamer Wasefy, Ebtisam R Qasem et autres

Background: FGL1 (Fibrinogen-like-protein 1), is synthesized by the liver .It was over-expressed in HCC. It triggers metabolism and promotes tissue proliferation .T cell are down regulated by PD-1 binding which is present on cell surface of malignant hepatocyte in HCC. Checkpoint inhibitors …

Égypte (code pays fourni par la source)

Prognostic significance of APOE and FOXP3 immunohistochemical expression in papillary thyroid carcinoma and concomitant Hashimoto’s thyroiditis

Heba Mahmoud Abdelgeleel, Ebtisam R Qasem, Ihab Matar, Adel A Elnossiry et autres

Background: APOE is involved in immunological control mediated by lymphocytes. The biological processes of several malignant tumors were accelerated by its overexpression. APOE reduces antigen-activated lymphocytes, which has an impact on immunity. Regulatory T cells (Treg) are a subset of T helper …

Égypte, us (code pays fourni par la source)

Clinicopathological discrepancy of oral cavity cancer before and after surgery

Eslam Abozaid, Ahmed Hassan Sweed, Mohammed R Asar, Ebtisam R Qasem et autres

Background: oral cavity cancers are not uncommon types of malignancies, with surgery still a corner stone in its local control. Discrepancy between post-operative pathological findings and pre-operative ones are eminent feature in this malignancy group, which in turn needs to be considered …

Égypte (code pays fourni par la source)

Incisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART)

Jared Torkington, Rhiannon Harries, Susan O’Çonnell, Laura Knight et autres

BACKGROUND: Incisional hernias cause morbidity and may require further surgery. HART (Hughes Abdominal Repair Trial) assessed the effect of an alternative suture method on the incidence of incisional hernia following colorectal cancer surgery. METHODS: A pragmatic multicentre single-blind RCT allocated patients undergoing …

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EP-1926 Radiomics in rectal cancer: prognostic significance of 3D features extracted from diagnostic MRI

Concetta Piazzese, P. Whybra, Ebtisam R Qasem, Diane Harris et autres

Inflammatory cell ratios predict major septic complications following rectal cancer surgery

H Jones, Ebtisam R Qasem, Nafi Dilaver, Richard Egan et autres

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Small Cell Carcinoma of the Rectum, ASystematic Literature Review and Case Series

Ebtisam R Qasem, M Nangalia, Horace C. Jones, Paul Griffiths et autres

Small cell carcinoma (SCC) is a rare malignancy that can affect the gastrointestinal tract. Current knowledge is limited to individual case series. Here we present three cases from our own institution and report the results of a systematic review of the literature. …

Outcomes following prosthetic patch repair in newborns with congenital diaphragmatic hernia

Wajid Jawaid, Ebtisam R Qasem, Matthew Jones, N. Shaw et autres

BACKGROUND: The anatomical defect in congenital diaphragmatic hernia (CDH) can usually be closed primarily but prosthetic patch repair may be required in newborns with a deficient diaphragm. High rates of patch failure and hernia recurrence (up to 50 per cent) have been …

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