Accès ouvert déclaré
2021
article
Patterns of etanercept use in juvenile idiopathic arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry
Timothy Beukelman, Aimee Lougee, Roland Matsouaka, David H. Collier, Dax G. Rumsey, Jennifer Schenfeld, Scott Stryker, Marinka Twilt, Yukiko Kimura, N. Abel, K. Abulaban, Andrew Adams, Matthew Adams, R. Agbayani, J. Aiello, Shoghik Akoghlanian, C. Alejandro, E. Allenspach, Risa Alperin, M. Alpizar, G. Amarilyo, William G Ambler, E. Anderson, Stacy P. Ardoin, S. Armendariz, Emma H. Baker, I. Balboni, Stephen J. Balevic, L. Ballenger, S. Ballinger, Nayimisha Balmuri, Fatima Barbar‐Smiley, L. Barillas-Arias, Matthew L. Basiaga, Kevin Baszis, M. Becker, H. Bell-Brunson, E. Beltz, Heather Benham, Susanne M. Benseler, William Bernal, T. Bigley, B. Binstadt, C. Black, Michael Blakley, J. Bohnsack, J. Boland, Alexis Boneparth, Simon Bowman, Claudia Bracaglia, Elizabeth B. Brooks, M. Brothers, A. G. P. Brown, H. Brunner, M. Buckley, Hülya Bükülmez, Danielle R. Bullock, B. Cameron, Scott Canna, Laura Cannon, P. Carper, Victoria Cartwright, Elaine Cassidy, L. Cerracchio, E. Chalom, Joyce C. Chang, A. Chang-Hoftman, V. Chauhan, Peter Chira, T. Chinn, K. Chundru, H. Clairman, D. Co, A. Confair, H. Conlon, R. Connor, Ashley M. Cooper, Jennifer C. Cooper, Sara Cooper, C. Correll, R. Corvalan, D. Costanzo, Randy Q. Cron, L. Curiel-Duran, T. Curington, M. Curry, Annette Dalrymple, Alaina M. Davis, Christopher Davis, T. Davis, Fabrizio De Benedetti, Deirdre De Ranieri, Jay B. Dean, F. Dedeoglu, M. DeGuzman, N. Delnay, V. Dempsey, E. DeSantis, T. Dickson, J. Dingle, Brittany Donaldson, E. Dorsey, Saunya Dover, J. Dowling, J. Drew, K. Driest, Qing Du, K. Duarte, D. Durkee, Eric Duverger, J. Dvergsten, A. Eberhard, M. Eckert, Kaleo Ede, B. Edelheit, Cuoghi Edens, Y. Edgerly, M. Elder, B. Ervin, S. Fadrhonc, C. Failing, Danielle C. Fair, M. Falcon, Leslie Favier, S. Federici, Brian M. Feldman, J. Fennell, Ian Ferguson, Polly J. Ferguson, B. Ferreira, R. Ferrucho, Kara G. Fields, Terri H. Finkel, M. Fitzgerald, Craig Fleming, O. Flynn, L. Fogel, Emily M. Fox, Megan E. Fox, L. Franco, M. A. R. Freeman, K. Fritz, D. Sean Froese, R. Fuhlbrigge, J. Fuller, Nancy George, Kerstin Gerhold, Dana Gerstbacher, Mileka Gilbert, Miriah Gillispie‐Taylor, E. Giverc, C. Godiwala, Y. Ingrid Goh, Haseeb Goheer, Donald P. Goldsmith, E C Gotschlich, Alisa Gotte, Beth S. Gottlieb, C. Gracia, T. Brent Graham, Sriharsha Grevich, Tom Griffin, John Griswold, Alexei A. Grom, M. Guevara, P. Guittar, Marietta De Guzman, Marlene Hager, Timothy Hahn, O. Halyabar, E. Hammelev, M. Hance, A. Hanson, Liora Harel, S. Haro, Julia G. Harris, Onengiya Harry, E. Hartigan, Jonathan S. Hausmann, Arielle Hay, K. Hayward, J. Heiart, K. Hekl, Lauren A. Henderson, Michael Henrickson, Aimee O. Hersh, K. Hickey, P. Hill, S. Hillyer, L. Hiraki, M. Hiskey, Patricia M. Hobday, C. Hoffart, M. Holland, M. Hollander, Seungkwan Hong, M. J. Horwitz, Joyce Hsu, Adam M. Huber, Jennifer Huggins, Joyce Hui‐Yuen, Chien‐Hui Hung, J. Huntington, Anna Huttenlocher, Maria Ibarra, Lisa F. Imundo, C. Inman, Antonella Insalaco, Annette M. Jackson, Shaun W. Jackson, Karen James, Ginger Janow, J. Jaquith, S. Jared, Nicole Johnson, Jordan T. Jones, Karla Jones, Susan Jones, S. Joshi, Lawrence Jung, C. Justice, A. Justiniano, N. Karan, Katherine Kaufman, A. Kemp, Elizabeth A. Kessler, U. Khalsa, Bernadette Kienzle, S. Kim, D. Kingsbury, Maleewan Kitcharoensakkul, T. Klausmeier, K. E. Klein, Marisa Klein‐Gitelman, B. Kompelien, A. Kosikowski, L. Kovalick, J. Kracker, S. Kramer, C. Kremer, Jennifer C. Lai, J. Lam, Bianca Lang, Sivia Lapidus, B. Lapin, A. Lasky, D. Latham, Erica Lawson, Ronald M. Laxer, P. Lee, T. Lee, Laura Lentini, Melissa A. Lerman, Deborah M. Levy, S. Li, Scott M. Lieberman, L. Lim, C. Lin, Nicholas Ling, M. Lingis, Mindy S. Lo, Dan Lovell, D. Lowman, Nadia Luca, S. Lvovich, Casey Madison, Jacqueline A. Madison, Bashir Ahmad Malla, J. Maller, Michael A. Malloy, Melissa L. Mannion, C. Manos, L. Marques, A. Martyniuk, Thomas G. Mason, S. Mathus, Lindy McAllister, K. McCarthy, K. McConnell, E. McCormick, Deborah McCurdy, P. Mc Curdy Stokes, Sarayna S. McGuire, I. McHale, A. McMonagle, C. McMullen-Jackson, Esra Meidan, E. Mellins, E. Mendoza, R. Mercado, Angela Merritt, L. Michalowski, P. Miettunen, Marlene R. Miller, D. Milojevic, Emily Mirizio, E. Misajon, M. Mitchell, Renee Modica, S. Mohan, Karen D. Moore, L. Nandini Moorthy, Sarah E. Morgan, Esi Morgan DeWitt, C. Moss, T. Moussa, V. Mruk, A. Murphy, Eyal Muscal, R. Nadler, B. Nahal, Kavita Nanda, N. Nasah, Lorien Nassi, Simona Nativ, Marc D. Natter, Jessica Neely, B. Nelson, L. Newhall, Lawrence Ng, Jacqueline Nicholas, Rebecca Nicolai, P. Nigrovic, J. Nocton, B. Nolan, Edward J. Oberle, B. Obispo, B. O’Brien, Timothy O’Brien, O. Okeke, Melissa Oliver, Judyann C. Olson, Kathleen M. O’Neil, Karen Onel, Amir B. Orandi, M. Orlando, Shirley‐Ann Osei‐Onomah, R. Oz, E. Pagano, Amy S. Paller, Nancy Pan, S. Panupattanapong, Manuela Pardeo, J. Paredes, Andrew S. Parsons, Jayesh Patel, K. Pentakota, Peri H. Pepmueller, T. Pfeiffer, K. Phillippi, Denise Pires Marafon, Lori Ponder, Rajdeep Pooni, S. Prahalad, S. Pratt, S. Protopapas, B. Puplava, J. Quach, M. Quinlan-Waters, C. Egla Rabinovich, Suhas M. Radhakrishna, J. Rafko, J. Raisian, A. Rakestraw, Cristián Ramírez, E. Ramsay, Suzanne Ramsey, Rachel L. Randell, H. Reid, K. Remmel, A. Repp, A. Reyes, Al Richmond, Meredith Riebschleger, Sarah Ringold, M. Riordan, Mona Riskalla, M. Ritter, R. Rivas-Chacon, Angela Byun Robinson, E. Rodela, M. Rodriquez, K. Rojas, Tova Ronis, Margalit Rosenkranz, B. Rosolowski, H. Rothermel, Deborah Rothman, E. Roth-Wojcicki, Kelly Rouster‐Stevens, Tamar B. Rubinstein, Natasha M. Ruth, Nadine Saad, S. Sabbagh, E. Sacco, Rebecca E. Sadun, C. Sandborg, A. Sanni, L. Santiago, Aliese Sarkissian, S. Savani, Lisabeth V. Scalzi, Laura E. Schanberg, S. Scharnhorst, K. Schikler, A. Schlefman, Heinrike Schmeling, Kara Schmidt, E. Schmitt, R. Schneider, K. Schollaert-Fitch, Grant S. Schulert, T. Seay, C. Seper, J. Shalen, R. Sheets, A. Shelly, S. Shenoi, K. Shergill, J. Shirley, M. Shishov, C. Shivers, Earl D. Silverman, Nora G. Singer, Vidya Sivaraman, J. Sletten, Andrew Smith, Chelsey Smith, Jonathan P. Smith, Emily A. Smitherman, Jennifer B. Soep, Mary Beth F. Son, S. Spence, L. Spiegel, J. Spitznagle, R. Sran, Hemalatha Srinivasalu, H. Stapp, K. Steigerwald, Y. Sterba Rakovchik, Sara Stern, Anna Stevens, B. Stevens, R. Stevenson, Katie Stewart, C. Stingl, J. Stokes, M. Stoll, Elizabeth Stringer, Sangeeta Sule, J. Sumner, Robert P. Sundel, M. Sutter, Reema Syed, G. Syverson, A Szymański, Sarah F. Taber, Rotem Tal, Ajay Tambralli, A. Taneja, T. Tanner, S. Tapani, G. Tarshish, Stacey E. Tarvin, L. Tate, Alysha J. Taxter, Janalee Taylor, Michael A. Terry, Melissa Tesher, Akaluck Thatayatikom, B. Thomas, K. Tiffany, Tracy V. Ting, A. Tipp, D. Toib, Kathryn S. Torok, C. Toruner, Heather Tory, M. Toth, Shirley M. L. Tse, V. Tubwell, S. Uriguen, T. Valcarcel, Heather Van Mater, L. Vannoy, C. Varghese, N. Vasquez, K. Vazzana, Richard K. Vehe, Keila Veiga, J. Velez, James Verbsky, G. Vilar, N. Volpe, Emily von Scheven, S. Vora, Joël Wagner, Linda Wagner‐Weiner, Dawn M. Wahezi, H. Waite, J. Walker, Heather M. Walters, Theresa Wampler Muskardin, L. Waqar, Michael Waterfield, M. Watson, Amber Watts, Peter Weiser, Jennifer E. Weiss, P. Weiss, Elisa Wershba, Andrew J. White, Calvin L. Williams, A. Wise, Jennifer M. P. Woo, Leandra Woolnough, Tracey Wright, Eveline Y. Wu, Ali Yalçindağ, M. Yee, E. Yen, Rae S. M. Yeung, K. Yomogida, Qingzhao Yu, R. Zapata, A. Zartoshti, Andrew Zeft, R. Zeft, Y. Zhang, Yongdong Zhao, Alice Zhu, C. Zic
5Citations signalées, ce qui n’est pas une note de qualité
8Institutions déclarées
2Pays d’affiliation déclarés
Rattachement africain : us, ca.
Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: We aimed to characterize etanercept (ETN) use in juvenile idiopathic arthritis (JIA) patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. METHODS: The CARRA Registry is a convenience cohort of patients with paediatric onset rheumatic diseases, including JIA. JIA patients treated with ETN for whom the month and year of ETN initiation were available were included. Patterns of ETN and methotrexate (MTX) use were categorized as follows: combination therapy (ETN and MTX started concurrently), step-up therapy (MTX started first and ETN added later), switchers (MTX started and then stopped when or before ETN started), MTX add-on (ETN started first and MTX added later), and ETN only (no MTX use). Data were described using parametric and non-parametric statistics as appropriate. RESULTS: Two thousand thirty-two of the five thousand six hundred forty-one patients with JIA met inclusion criteria (74% female, median age at diagnosis 6.0 years [interquartile range 2.0, 11.0]. Most patients (66.9%) were treated with a non-biologic disease modifying anti-rheumatic drug (DMARD), primarily MTX, prior to ETN. There was significant variability in patterns of MTX use prior to starting ETN. Step-up therapy was the most common approach. Only 34.0% of persistent oligoarticular JIA patients continued treatment with a non-biologic DMARD 3 months or more after ETN initiation. ETN persistence overall was 66.3, 49.4, and 37.3% at 24, 36 and 48 months respectively. ETN persistence among spondyloarthritis patients (enthesitis related arthritis and psoriatic JIA) varied by MTX initiation pattern, with higher ETN persistence rates in those who initiated combination therapy (68.9%) and switchers/ETN only (73.3%) patients compared to step-up (65.4%) and MTX add-on (51.1%) therapy. CONCLUSION: This study characterizes contemporary patterns of ETN use in the CARRA Registry. Treatment was largely in keeping with American College of Rheumatology guidelines.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Patterns of etanercept use in juvenile idiopathic arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry
- Date Crossref
- 21/08/2021
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Les institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Les sujets associés
Autoimmune and Inflammatory Disorders ResearchRheumatoid Arthritis Research and TherapiesSpondyloarthritis Studies and Treatments